GAK Products

Description

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5.

Bioinformatics

Entrez	2580 Human
Uniprot	AAH08668 Human AAH08668.1 Human AAH63606 Human NM_005255 Human O14976 Human
Product By Gene ID	2580
Alternate Names	cyclin G associated kinase cyclin-G-associated kinase EC 2.7.11.1 FLJ16629 FLJ40395 MGC99654

Research Areas for GAK

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication