Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, KD
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Sheep Polyclonal
Species: Rt
Applications: IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AP
Description
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants.
Bioinformatics
| Entrez |
Rat
Human
Mouse
|
| Uniprot |
Human
Human
Human
Human
Rat
|
| Product By Gene ID |
2550 |
| Alternate Names |
- FLJ92613
- GABABR1
- GABBR1-3
- gamma-aminobutyric acid (GABA) B receptor, 1
- gamma-aminobutyric acid type B receptor subunit 1
- GB1
- Gb1
- GPRC3Asubunit 1c
- hGB1a
- seven transmembrane helix receptor
|
![Immunohistochemistry GABA-B R1 Antibody (751216) [Unconjugated]](http://images.novusbio.com/fullsize2/GABA_B_R1_MAB7000_Immunohistochemistry_12256.jpg)
