EIF4A3 Products

Description

EIF4A3 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

Bioinformatics

Entrez	9775 Human
Uniprot	NM_014740 Human NP_055555 Human NP_055555.1 Human P38919 Human
Product By Gene ID	9775
Alternate Names	ATP-dependent RNA helicase DDX48 ATP-dependent RNA helicase eIF4A-3 DDX48 DEAD (Asp-Glu-Ala-Asp) box polypeptide 48 DEAD box protein 48 DKFZp686O16189 EC 3.6.1 EC 3.6.4.13 eIF4AIII EIF4AIII eIF-4A-III eIF4A-III eukaryotic initiation factor 4A-III Eukaryotic initiation factor 4A-like NUK-34 Eukaryotic translation initiation factor 4A isoform 3 eukaryotic translation initiation factor 4A eukaryotic translation initiation factor 4A3 hNMP 265 KIAA0111eukaryotic translation initiation factor 4A, isoform 3 MGC10862 NMP 265 NMP265 Nuclear matrix protein 265 NUK34