DEGS1 Products

Description

DEGS1 encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified. [provided by RefSeq]

Bioinformatics

Entrez	8560 Human
Uniprot	NP_003667 Human NP_003667.1 Human O15121 Human
Product By Gene ID	8560
Alternate Names	Cell migration-inducing gene 15 protein Degenerative spermatocyte homolog 1 degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) degenerative spermatocyte homolog, lipid desaturase (Drosophila) DEGS Des-1 DES1degenerative spermatocyte homolog, lipid desaturase EC 1.14 FADS7 membrane fatty acid (lipid) desaturase Membrane lipid desaturase MGC5079 migration-inducing gene 15 protein MLDdihydroceramide desaturase sphingolipid delta 4 desaturase sphingolipid delta(4)-desaturase DES1