DAP10/HCST Products

Description

HCST encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms.

Bioinformatics

Entrez	10870 Human 23900 Mouse 474146 Rat
Uniprot	NM_001007469 Human NM_014266 Human NP_055081.1 Human
Product By Gene ID	10870
Alternate Names	DAP10PIK3AP DKFZP586C1522 hematopoietic cell signal transducer KAP10DNAX-activation protein 10 kinase assoc pro of ~10kDa kinase assoc protein Membrane protein DAP10 phosphoinositide-3-kinase adaptor protein Transmembrane adapter protein KAP10

Research Areas for DAP10/HCST

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Immune System Diseases
Immunology
Innate Immunity