Species: Hu
Applications: WB, IHC, ICC/IF
Host: Goat Polyclonal
Species: Hu
Applications: WB, IHC, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Disabled-2 (Dab2) is a component of the CSF-1 signal transduction pathway. Dab2 is involved in the regulation of cytoskeleton based functions by regulating cell positioning, inducing marcrophage adhesion, or regulation of protein trafficking of endocytosis involved proteins (1,2). Dab2 has been implicated in regulating the homeostasis of epithelial differentiation, where Dab2 is involved in endodermal cell formation, differentiation, and organization. Dab2 mRNA expression is common in normal ovarian epithelia cells but low or lack of expression is seen in ovarian carcinoma cell lines (3).
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
1601 |
| Alternate Names |
- Differentially-expressed protein 2
- disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)
- disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
- DOC-2DOC2disabled homolog 2
- FLJ26626
- mitogen-responsive phosphoprotein
|
Research Areas for DAB2
Find related products by research area and learn more about each of the different research areas below.
Neuroscience
