COPS8 Products

Description

COPS8 is encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Bioinformatics

Entrez	10920 Human
Uniprot	AAH03090 Human NM_006710 Human NM_198189 Human NP_006701 Human NP_006701.1 Human Q99627 Human
Product By Gene ID	10920
Alternate Names	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) COP9 homolog COP9 signalosome complex subunit 8 COP9 CSN8JAB1-containing signalosome subunit 8 hCOP9 MGC1297 MMMEP SGN8MGC43256 Signalosome subunit 8

Research Areas for COPS8

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism