Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, ICC/IF, IP, MA
Host: Mouse Monoclonal
Species: Hu, Pm
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins). Cdc7 kinase was also found to be important in meiosis, checkpoint responses, maintenance of chromosome structure, and repair.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
8317 |
| Alternate Names |
- CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1
- CDC7 cell division cycle 7 (S. cerevisiae)
- CDC7L1MGC117361
- CDC7-related kinase
- cell division cycle 7 (S. cerevisiae)
- cell division cycle 7 homolog (S. cerevisiae)
- cell division cycle 7-like protein 1
- cell division cycle 7-related protein kinase
- EC 2.7.11.1
- HsCdc7
- HsCDC7
- Hsk1
- huCdc7
- huCDC7
- MGC126237
- MGC126238
|
