CD79B Products

Description

Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79alpha/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (1)

Bioinformatics

Entrez	15985 Mouse 171055 Rat 974 Human
Uniprot	AAH32651 Human NM_000626 Human NM_001039933 Human NP_000617 Human NP_000617.1 Human P15530 Mouse P40259 Human
Product By Gene ID	974
Alternate Names	B29B-cell-specific glycoprotein B29 B-cell antigen receptor complex-associated protein beta chain CD79B antigen (immunoglobulin-associated beta) CD79b antigen CD79b molecule, immunoglobulin-associated beta IGBAGM6 Ig-beta Immunoglobulin-associated B29 protein

Related CD79B Blog Posts

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CD79b - A Signal Transduction Component of the B-cell Receptor The B-cell antigen receptor (BCR) is a complex multimeric aggregate that includes the following key noncovalently-bound components: antigen-specific surface immunoglobulin (Ig), CD79a (Ig-alpha), and CD79b (Ig-beta). BCR signaling is a pivotal pathway...    Read more.

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