CaM Kinase I Products

Description

Ca(+2)/calmodulin-dependent protein kinases (CaMKs) are activated upon binding of Ca(+2)/calmodulin. To gain maximal activity, CaMK I and CaMK IV can be further phosphorylated by an upstream kinase, CaMK kinase (CaMKK) (1). CaMKI is a Ca2+/calmodulin-dependent protein kinase that is widely expressed in eukaryotic cells and tissues but for which few, if any, physiological substrates are known (2). CaMKI has been shown to comprise a family of four structurally related isoforms (alpha, beta, gamma, and delta) encoded by separate genes with abundant expression in mature brain. In mouse brain, the four isoforms of CaMKI were found to exhibit distinct spatiotemporal expression during neuronal development. CaMKI may also have possible functional involvement of in the basal dendritic growth of hippocampal neurons (3)

Bioinformatics

Entrez	171503 Rat 52163 Mouse 8536 Human
Uniprot	NM_003656 Human NP_003647 Human Q14012 Human
Product By Gene ID	8536
Alternate Names	calcium/calmodulin-dependent protein kinase I calcium/calmodulin-dependent protein kinase type 1 CaM kinase I alpha CaM kinase I CaMKI CAMKI CaM-KI caM-KI caMKI-alpha CaMKI-alpha EC 2.7.11 EC 2.7.11.17 MGC120317 MGC120318

Research Areas for CaM Kinase I

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Protein Kinase
Sensory Systems
Vision