BMPR-IB/ALK-6 Products

Description

BMPR1B encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.

Bioinformatics

Entrez	658 Human
Uniprot	AAH47773 Human AAH47773.1 Human NP_001194 Human NP_001194.1 Human O00238 Human
Product By Gene ID	658
Alternate Names	activin receptor-like kinase 6 ALK-6 ALK6CDw293 BMP type-1B receptor BMPR-1B bone morphogenetic protein receptor type-1B bone morphogenetic protein receptor, type IB CDw293 antigen EC 2.7.11 EC 2.7.11.30 serine/threonine receptor kinase

Research Areas for BMPR-IB/ALK-6

Find related products by research area and learn more about each of the different research areas below.

Mesenchymal Stem Cell Markers
Protein Kinase
Stem Cell Markers