BLIMP1/PRDM1 Products

Description

Blimp-1 (B lymphocyte maturation protein-1) is a transcriptional repressor that is required to trigger terminal differentiation of B lymphocytes into Ig secreting cells. Therefore, Blimp 1 is generally considered a "master regulator" for hematopoietic stem cells.

Blimp1 is a nuclear protein with five zinc fingers in its carboxy terminus. The Blimp-1 protein is expressed in, and may be required for terminally differentiated epithelial cells, retinal neurons and other lineage cells. BLIMP-1 has also been implicated in the repression of beta-interferon (IFN-beta) and c-myc gene expression.

Bioinformatics

Entrez	12142 Mouse 639 Human
Uniprot	NP_001189 Human NP_001189.2 Human NP_878911 Human O75626 Human Q60636 Mouse
Product By Gene ID	639
Alternate Names	Beta-interferon gene positive regulatory domain I-binding factor beta-interferon gene positive-regulatory domain I binding factor BLIMP-1 BLIMP1MGC118925 blmp-1 B-lymphocyte-induced maturation protein 1 MGC118922 MGC118923 Positive regulatory domain I-binding factor 1 PR domain containing 1, with ZNF domain PR domain zinc finger protein 1 PR domain-containing protein 1 PRDI-BF1MGC118924 PRDI-binding factor 1 PRDI-binding factor-1 PR-domain zinc finger protein 1

Research Areas for BLIMP1/PRDM1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Chromatin Research
Cytokine Research
Diabetes Research
Immune System Diseases
Immunology
Innate Immunity
Zinc Finger

Related BLIMP1/PRDM1 Blog Posts

Check out the latest blog posts on BLIMP1/PRDM1.

Tired T cells: Hypoxia Drives T cell Exhaustion in the Tumor Microenvironment By Hunter MartinezThe paradigm shifting view of the immune system being leveraged to target cancer has led to numerous therapeutic breakthroughs. One major cell group responsible for this revelation is a T cell. ...    Read more.

Read more BLIMP1/PRDM1 related blogs.