Species: Mu
Applications: WB, IHC
Host: Goat Polyclonal
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
MASH1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Bioinformatics
Entrez |
Mouse Human Rat |
Uniprot |
Human Human Human Human |
Product By Gene ID |
429 |
Alternate Names |
- achaete-scute complex (Drosophila) homolog-like 1
- achaete-scute complex homolog 1 (Drosophila)
- achaete-scute complex-like 1 (Drosophila)
- achaete-scute homolog 1
- ASH-1
- ASH1MASH1
- BHLHA46
- bHLHa46achaete-scute complex-like 1
- Class A basic helix-loop-helix protein 46
- hASH1
- HASH1achaete scute protein
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Research Areas for ASCL1/Mash1
Find related products by research area and learn more about each of the different research areas below.
Neuroscience