ARHGEF7 Products

Description

ARHGEF7, also known as Rho guanine nucleotide exchange factor 7, contains many isoforms that are 90 kDa, 87 kDa, 84 kDa, 82 kDa, 73 kDa, and 70 kDa, and is involved in apoptosis regulation, cell migration, and cell spreading. Current disease research is being conducted on ARHGEF7 and its relation to Borjeson-Forssmann-Lehmann Syndrome, t-cell leukemia, breast cancer, Wiskott-Aldrich Syndrome, insulin resistance, neuronitis, pancreatitis, leukemia, neuroblastoma, insulin resistance, adenocarcinoma, and lung cancer. This protein is linked to the GPCR pathway and the RhoA pathway, and it interacts with SCRIB, CBL, GIT1, PAK1, and CBLB.

Bioinformatics

Entrez	8874 Human
Uniprot	NP_001106985 Human NP_003890 Human NP_003890.1 Human NP_663788 Human Q14155 Human
Product By Gene ID	8874
Alternate Names	Beta-Pix COOL1COOL-1 DKFZp686C12170 DKFZp761K1021 guanine nucleotide exchange factor 7 KIAA0142KIAA0412 Nbla10314 P50 P50BP p85 P85 P85COOL1 P85SPRBETA-PIX PAK3 PAK3BP PIXBPAK-interacting exchange factor beta Rho guanine nucleotide exchange factor (GEF) 7 rho guanine nucleotide exchange factor 7 SH3 domain-containing proline-rich protein