AOC2 Products

Description

Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.

Bioinformatics

Entrez	314 Human
Uniprot	NM_001158 Human NP_033720 Human NP_033720.2 Human O75106 Human
Product By Gene ID	314
Alternate Names	Amine oxidase [copper-containing] amine oxidase, copper containing 2 (retina-specific) DAO2 EC 1.4.3 RAOEC 1.4.3.21 retina-specific copper amine oxidase Semicarbazide-sensitive amine oxidase SSAO

Research Areas for AOC2

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Vision