Species: Hu
Applications: WB, IP
Host: Goat Polyclonal
Species: Mu
Applications: WB, ELISA(Cap)
Host: Goat Polyclonal
Species: Hu
Applications: WB, Simple Western
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: AC
Description
LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the insulin receptor subfamily of kinases. LTK (leukocyte tyrosine kinase) is expressed in murine B lymphocyte precursors and has also been found in forebrain neurons. ALK (anaplastic lymphoma kinase) is normally highly expressed, specifically in the nervous system. A truncated form containing the catalytic domian of ALK is expressed as the result of a translocation occurring in many non-Hodgkin's lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.
Bioinformatics
Entrez |
Mouse Rat Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
94 |
Alternate Names |
- activin A receptor type II-like 1
- activin A receptor, type II-like kinase 1
- Activin receptor-like kinase 1
- ACVRLK1ORW2
- ALK-1
- ALK1TGF-B superfamily receptor type I
- EC 2.7.11
- HHT
- HHT2EC 2.7.11.30
- serine/threonine-protein kinase receptor R3
- SKR3
- TSR-I
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Research Areas for ALK-1
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Protein Kinase