Adenine Nucleotide Translocator 2 Products

Description

ADP/ATP translocase, the most abundant mitochondrial protein, is an integral component of the inner mitochondrial membrane. It facilitates exchange of ADP and ATP between the cytosol and the mitochondria, thereby linking the subcellular compartment of ATP production to those of ATP utilization. SLC25A5 is 1 of at least 3 transcriptionally active ADP/ATP translocase genes in humans (Chen et al., 1990 [PubMed 2157297]). Battini et al. (1987) [PubMed 3031073] cloned an ADP/ATP translocase gene from an Okayama-Berg library derived from SV40-transformed human fibroblasts. Ku et al. (1990) [PubMed 2168878] cloned and sequenced the ANT2 gene. Chen et al. (1990) [PubMed 2157297] isolated 7 ADP/ATP translocase pseudogenes from recombinant human genomic libraries. Each pseudogene sequence had more than 85% identity with the sequence of the translocase cDNA derived from fibroblast mRNA, but each had mutations that precluded synthesis of a functional protein.[supplied by OMIM]

Bioinformatics

Entrez	292 Human
Uniprot	AAH56160 Human NM_001152 Human NP_001143 Human
Product By Gene ID	292
Alternate Names	adenine nucleotide translocator 2 (fibroblast) Adenine nucleotide translocator 2 ADP ADP ADP/ATP carrier protein ADP/ATP translocase 2 ANT2AAC2, 2F1 ATP carrier protein 2 ATP carrier protein, fibroblast isoform solute carrier family 25 (mitochondrial carrier; adenine nucleotidetranslocator), member 5 Solute carrier family 25 member 5 T2 T3ANT 2

Research Areas for Adenine Nucleotide Translocator 2

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Core ESC-Like Genes
Stem Cell Markers