ACCN1 Products

Description

FUNCTION: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.; SUBUNIT: Homotetramer or heterotetramer with other ASIC proteins. Interacts with STOM. Interacts with PRKCABP and ACCN3.; SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Note: Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes.

Bioinformatics

Entrez	11418 Mouse 25364 Rat 40 Human
Uniprot	NM_001094 Human Q925H0 Mouse
Product By Gene ID	40
Alternate Names	Acid-sensing ion channel 2 Amiloride-sensitive brain sodium channel amiloride-sensitive cation channel 1, neuronal ASIC2a ASIC2Mammalian degenerin homolog BNAC1 BNaC1ACCN BNC1Amiloride-sensitive cation channel neuronal 1 degenerin hBNaC1 MDEGBrain sodium channel 1 neuronal amiloride-sensitive cation channel 1