53BP2 Products

Description

53BP2 encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Entrez	7159 Human
Uniprot	AAH58918 Human NP_001026855 Human Q13625 Human
Product By Gene ID	7159
Alternate Names	apoptosis-stimulating protein of p53, 2 ASPP2P53BP2,53BP2apoptosis-stimulating of p53 protein 2 Bbp BBP Bcl2-binding protein p53-binding protein 2 p53BP2 PPP1R13A Renal carcinoma antigen NY-REN-51 tumor protein p53 binding protein, 2 tumor protein p53-binding protein, 2 Tumor suppressor p53-binding protein 2

Research Areas for 53BP2

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
DNA Repair
Tumor Suppressors