5-HT2A Products

Description

The 5HT2A Receptor gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene areassociated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated withresponse to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also havea mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressantdownregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found forthis gene. (provided by RefSeq)

Bioinformatics

Entrez	3356 Human
Uniprot	NP_000612.1 Human P28223 Human
Product By Gene ID	3356
Alternate Names	5-HT2 receptor 5-HT-2 5-HT-2A 5-hydroxytryptamine (serotonin) receptor 2A 5-hydroxytryptamine receptor 2A HTR2,5-HT2A serotonin 5-HT-2A receptor Serotonin receptor 2A

Research Areas for 5-HT2A

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GPCR