Caspase-7 Products

Description

Caspase 7 (CASP7) is a member of the cysteine-aspartic acid protease (caspase) family that is involved in the execution-phase of cell apoptosis. The sequential activation of caspases plays a central role in the execution-phase of cell apoptosis, and Caspase 7 is an executioner protein of apoptosis. It is activated upon cell death stimuli and induces apoptosis.

Caspase 7 is expressed as an inactive proenzyme which then undergos proteolytic processing by upstream caspases, to form an active (cleaved) caspase 7 form.

Caspase 7 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.

Bioinformatics

Entrez	12369 Mouse 64026 Rat 840 Human
Uniprot	AAH15799 Human B4DQU7 Human BAG61059 Human NM_001227 Human NM_033339 Human NP_001218 Human NP_001218.1 Human NP_203126 Human P55210 Human
Product By Gene ID	840
Alternate Names	apoptosis-related cysteine protease Apoptotic protease Mch-3 CASP-7 caspase 7, apoptosis-related cysteine peptidase caspase-7 EC 3.4.22 EC 3.4.22.60 ICE-like apoptotic protease 3 Lice2 alpha/beta/gamma

Research Areas for Caspase-7

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Caspases
Cell Biology
Cellular Markers
Ubiquitin Proteasome Pathway

Related Caspase-7 Blog Posts

Check out the latest blog posts on Caspase-7.

The Ins and Outs of Survivin By Rachel M.A. Linger, Ph.D.What is survivin?Survivin is a small (16.5 kDa) protein normally found in human fetal tissue. In contrast, survivin is typically undetectable in most normal adult tissues. Expression of ...    Read more.

Pyroptosis: Mechanisms mediating cell death and pro-inflammatory cytokine release By Victoria OsinskiPyroptosis is an inflammatory form of programmed cell death characterized by the release of pro-inflammatory cytokines IL-1 beta and IL-18.1,10 It is a process distinct from apoptosis and necrosis (T...    Read more.

Caspase 7 - A key effector of the apoptotic pathway Caspase-7 is an effector caspase with important roles in mediating cell death signaling. As an effector caspase, caspase-7 is cleaved and activated by initiator caspases such as caspase-1 (1). Like other caspase family proteins, caspase-7 contains a...    Read more.

Read more Caspase-7 related blogs.