beta-Arrestin 1 Products

Description

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization ofG-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones,neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in thebeta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the centralnervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin systemis believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcriptsencoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.(provided by RefSeq)

Bioinformatics

Entrez	109689 Mouse 25387 Rat 408 Human
Uniprot	AAH03636 Human NM_004041 Human NP_004032.2 Human P49407 Human
Product By Gene ID	408
Alternate Names	ARB1 ARR1 arrestin 2 Arrestin beta-1 arrestin, beta 1 beta-arrestin-1

Research Areas for beta-Arrestin 1

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Signal Transduction
Virology, Bacteria and Parasites