Mouse IgG1 Isotype Control (MOPC-21) [DyLight 488]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-36577G
    • Availability
      Product Discontinued

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Mouse IgG1 Isotype Control (MOPC-21) [DyLight 488] Summary

Description
This Mouse IgG1 (MOPC-21) immunoglobulin is useful as an isotype control for Mouse IgG1 (MOPC-21) antibody.
Specificity
This antibody has unknown specificity and was chosen as an isotype control after screening on variety of resting, activated, live and fixed rat and human tissues.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Purity
SDS-PAGE

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Use the isotype control at the same concentration as the experimental antibody. Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Borate
Preservative
0.05% Sodium Azide
Purity
SDS-PAGE

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Mouse IgG1 Isotype Control (MOPC-21) [DyLight 488]

  • IgG1
  • Igh-4
  • RGD1359539
  • VH7183

Background

IgG is a monomeric immunoglobulin composed of two heavy chains and two light chains. There are four subclasses of the IgG: IgG1, IgG2, IgG3 and IgG4. Each molecule has two antigen binding sites. IgG is the most abundant immunoglobulin as well as the only isotype that can pass through the placent,a thereby providing protection to the fetus in its first weeks of life before, its own immune system has developed. IgG can bind to several different kinds of pathogens, for example viruses, bacteria and fungi, and it protects the body against them by complement activation (the classic pathway), opsonization for phagocytosis and neutralization of their toxins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

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Research Areas for IgG1 Isotype Control (NBP2-36577G)

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CD16 is a lymphocyte Fc gamma type III low-affinity receptor for IgG and is represented by two similar genes, CD16A (Fc gamma RIII A) and CD16B (Fc gamma RIIIB). CD16A exists as a heterooligomeric polypeptide-anchored form in macrophages and NK cells....  Read full blog post.

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