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VPS4B Antibody [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 405

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VPS4B Antibody [DyLight 405] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 300 and 350 of human vacuolar protein sorting 4 homolog B using the numbering given in entry NP_004860.2 (GeneID 9525).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
VPS4B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for VPS4B Antibody [DyLight 405]

  • Cell migration-inducing gene 1 protein
  • Protein SKD1
  • SKD1B
  • SKD1cell migration-inducing 1
  • Suppressor of K(+) transport growth defect 1
  • suppressor of K+ transport defect 1
  • vacuolar protein sorting 4 homolog B (S. cerevisiae)
  • vacuolar protein sorting 4B (yeast)
  • vacuolar protein sorting 4B
  • vacuolar protein sorting-associated protein 4B
  • VPS42
  • VPS4-2

Background

VPS4B is encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol VPS4B