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UBR1 Antibody

Images

 
Western Blot: UBR1 Antibody [NBP3-12361] - A. PC-UBR1, B. Rat midbrain extract. Antibody diluted 1:500 in DiluObuffer. Apparent MW IS 210 KDa.
Immunohistochemistry-Paraffin: UBR1 Antibody [NBP3-12361] - Rat Kidney. 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.
Western Blot: UBR1 Antibody [NBP3-12361] - Mouse Cerebellum. 1:500 antibody dilution in DiluObuffer. Apparent MW is 210-215 KDa.
Immunohistochemistry-Paraffin: UBR1 Antibody [NBP3-12361] - Mouse Skeletal Muscle. 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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UBR1 Antibody Summary

Immunogen
Synthetic peptide taken within amino acid region 1260-1500 on human UBR1 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
UBR1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:4000
  • Immunohistochemistry 1:50-1:150
  • Immunohistochemistry-Paraffin 1:50-1:150
  • Immunoprecipitation 1:150
  • Western Blot 1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for UBR1 Antibody

  • E3 ubiquitin-protein ligase UBR1
  • E3a ligase
  • EC 6.3.2.-
  • JBS
  • MGC142065
  • MGC142067
  • N-recognin-1
  • ubiquitin ligase E3 alpha-I
  • ubiquitin protein ligase E3 component n-recognin 1
  • ubiquitin-protein ligase E3-alpha
  • Ubiquitin-protein ligase E3-alpha-1
  • Ubiquitin-protein ligase E3-alpha-I

Background

The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol UBR1