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Trypsin 3/PRSS3 Antibody (419910)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clone
419910
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price
Carrier Free
MAB35651-SP
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Trypsin 3/PRSS3 Antibody (419910) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Trypsin 3/PRSS3
Phe16-Asn246
Accession # NP_035775
Specificity
Detects mouse Trypsin 3/PRSS3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, weak cross-reactivity with recombinant human (rh) Trypsin 3 is observed and no cross-reactivity with rhTrypsin 1 or rhTrypsin 2 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
PRSS3
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Trypsin 3/PRSS3 Antibody (419910)

  • Brain trypsinogen
  • EC 3.4.21
  • EC 3.4.21.4
  • Mesotrypsin
  • mesotrypsinogen
  • MTG
  • pancreatic trypsinogen III
  • protease, serine, 3 (mesotrypsin)
  • protease, serine, 3
  • protease, serine, 4 (trypsin 4, brain)
  • PRSS3
  • PRSS4
  • Serine protease 3
  • Serine protease 4
  • T9
  • TRY3MTG
  • TRY4mesotrypsin
  • Trypsin 3
  • Trypsin 4
  • Trypsin III
  • Trypsin IV
  • trypsin-3
  • Trypsinogen 15
  • trypsinogen 4
  • trypsinogen 5
  • trypsinogen IV

Background

Trypsin 3, encoded by the PRSS3 gene and also known as mesotrypsin is a serine protease and is one of three pancreatic Trypsins. It constitutes less than 10% of the total Trypsin content in normal pancreatic juice. Trypsin 3 is activated by enterokinase cleavage of the 8 aa pro region and secreted into the duodenum lumen. Trypsin 3 is highly resistance to polypeptide Trypsin inhibitors, and may degrade them in foods to facilitate digestion. The 223 amino acid mature mouse Trypsin 3 shares 78% and 96% aa identity with human and rat Trypsin 3, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Trypsin 3/PRSS3
Antibody (419910)
MAB35651
Trypsin 3/PRSS3 Antibody (419910)
Species: Mu
Applications: WB

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Bioinformatics

Gene Symbol PRSS3
Uniprot