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TNP1 Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: TNP1 Antibody [NBP2-30567] - Staining in human testis and fallopian tube tissues using anti-TNP1 antibody. Corresponding TNP1 RNA-seq data are presented for ...read more
Immunohistochemistry-Paraffin: TNP1 Antibody [NBP2-30567] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: TNP1 Antibody [NBP2-30567] - Staining of human fallopian tube shows low expression as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

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TNP1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: STSRKLKSHGMRRSKSRSPHKGVKRGGSKRKYRKGNLKSRKRGDDANRNYRSHL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TNP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
TNP1 Protein (NBP2-30567PEP)
Publications
Read Publication using NBP2-30567.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (87%). Reactivity reported in scientific literature (PMID: 24598113)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TNP1 Antibody

  • spermatid nuclear transition protein 1
  • STP-1
  • TP1
  • TP-1
  • transition protein 1 (during histone to protamine replacement)

Background

Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TNP1 Antibody (NBP2-30567)(1)

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Bioinformatics

Gene Symbol TNP1
Uniprot