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SMCX Antibody

Images

 
Western Blot: SMCX Antibody [NBP2-55541] - Analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.
Immunocytochemistry/ Immunofluorescence: SMCX Antibody [NBP2-55541] - Staining of human cell line HEK 293 shows localization to nucleoplasm.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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SMCX Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EELEPKRVRSSGPEAEEVQEEEELEEETGGEGPPAPIPTTGSPSTQENQNGLEPAEGTTSGPSAPFSTLTPRLH
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KDM5C
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Western Blot 0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
SMCX Recombinant Protein Antigen (NBP2-55541PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for SMCX Antibody

  • DXS1272E
  • DXS1272EMRXJ
  • EC 1.14.11
  • EC 1.14.11.-
  • Histone demethylase JARID1C
  • JARID1C
  • JARID1Clysine-specific demethylase 5C
  • Jumonji, AT rich interactive domain 1C (RBP2-like)
  • jumonji, AT rich interactive domain 1C
  • Jumonji/ARID domain-containing protein 1C
  • KDM5C
  • lysine (K)-specific demethylase 5C
  • MRXSJ
  • Protein SmcX
  • Protein Xe169
  • Smcx homolog, X chromosome
  • SMCX
  • SMCXselected cDNA on X
  • Smcy homolog, X-linked (mouse)
  • Smcy homolog, X-linked
  • XE169
  • XE169JmjC domain-containing protein SMCX

Background

SMCX is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol KDM5C