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SETD7/9 Antibody (7C1B7E1) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
7C1B7E1
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

Order Details

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SETD7/9 Antibody (7C1B7E1) [mFluor Violet 610 SE] Summary

Immunogen
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SETD7/9 (Accession#: NP_085151.1; Asp 2-Lys 366).
Specificity
No cross-reactivity in ELISA with:

E.coli cell lysate
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
SETD7
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

No cross-reactivity in ELISA with:

E.coli cell lysate

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SETD7/9 Antibody (7C1B7E1) [mFluor Violet 610 SE]

  • EC 2.1.1.43
  • H3-K4-HMTase SETD7
  • histone H3-lysine 4-specific methyltransferase
  • histone-lysine N-methyltransferase SETD7
  • KIAA1717SET domain-containing protein 7
  • KMT7FLJ21193
  • Lysine N-methyltransferase 7
  • SET domain containing (lysine methyltransferase) 7
  • SET7/9Histone H3-K4 methyltransferase SETD7
  • SET7Set9
  • SET9

Background

Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly(ADP-ribosylation), ubiquitination and methylation. These modifications play critical roles in regulating chromatin structure and gene expression. Histone methyltransferases (HMTases) selectively methylate evolutionarily conserved arginine or lysine residues, primarily in the N-terminal tails of histones H3 and H4. Set7/9 is a histone specific HMTase that methylates histone H3 lysine 4. Set7/9 transfers methyl groups to lysine 4 of histone H3 in complex with S-adenosyl-L-methionine. Human Set7/9 is a 336 amino acid protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional SETD7/9 Products

Array NBP3-06625MFV610

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Bioinformatics

Gene Symbol SETD7