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S1P4/EDG-6 Antibody (1012512) [Unconjugated]

Images

 
HEK293 human embryonic kidney cell line transfected with either (A) human S1P4/EDG-6 or (B) irrelevant protein and eGFP was stained with Mouse Anti-Human S1P4/EDG-6 Monoclonal Antibody (Catalog # MAB10321) followed by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
1012512
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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S1P4/EDG-6 Antibody (1012512) [Unconjugated] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human S1P4/EDG‑6
Met1-Ile384
Accession # O95977
Specificity
Detects human S1P4/EDG‑6 transfectants but not the parental cell line in Flow Cytometry.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for S1P4/EDG-6 Antibody (1012512) [Unconjugated]

  • EDG6
  • EDG6S1P receptor Edg-6
  • Endothelial differentiation G-protein coupled receptor 6
  • endothelial differentiation, G-protein-coupled receptor 6
  • endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor6,endothelial differentiation, G protein coupled receptor 6
  • S1P receptor 4
  • S1P4
  • S1P4LPC1
  • S1PR4
  • SLP4
  • sphingosine 1-phosphate receptor 4
  • Sphingosine 1-phosphate receptor Edg-6
  • sphingosine-1-phosphate receptor 4

Background

EDG-6 belongs to the G protein-coupled receptor 1 family. It is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. EDG-6 is a receptor for the lysosphingolipid sphingosine 1- phosphate (S1P), a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. EDG-6 may be involved in cell migration processes that are specific for lymphocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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