Prostaglandin E2 Parameter Assay Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Prostaglandin E2 (PGE2) is formed in a variety of cells from prostaglandin H2, which is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. PGE2 has a number of biological actions, including vasodilation, both anti- and proinflammatory action, modulation of sleep/wake cycles, and facilitation of human immunodeficiency virus replication. It elevates cAMP levels, stimulates bone resorption and has thermoregulatory effects. It has been shown to be a regulator of sodium excretion and renal hemodynamics.

We have publications tested in 14 confirmed species: Human, Mouse, Rat, Bovine, Camel, Canine, Equine, Fungus, Porcine, Primate - Macaca mulatta (Rhesus Macaque), Rabbit, Tick, Tinospora crispa, Xenograft.

We have publications tested in 1 application: Bioassay.

Showing Publications 1 - 10 of 418. Show All 418 Publications. Collapse Publications.

Publications using KGE004B	Applications	Species
Jung, JS;Choi, GH;Lee, H;Ko, Y;Ji, S; The Clinical Effect of a Propolis and Mangosteen Extract Complex in Subjects with Gingivitis: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial Nutrients 2024-09-05 [PMID: 39275315] (Human)		Human
Takacs, GP;Garcia, JS;Hodges, CA;Kreiger, CJ;Sherman, A;Harrison, JK; CSF1R Ligands Expressed by Murine Gliomas Promote M-MDSCs to Suppress CD8+ T Cells in a NOS-Dependent Manner Cancers 2024-09-01 [PMID: 39272914] (Mouse)		Mouse
Kang, W;Xu, Q;Dong, H;Wang, W;Huang, G;Zhang, J; Eriodictyol attenuates osteoarthritis progression through inhibiting inflammation via the PI3K/AKT/NF-?B signaling pathway Scientific reports 2024-08-14 [PMID: 39143134] (Human)		Human
Yang, C;Yang, H;Kim, H;Chung, N;Shin, J;Min, H;Lee, K;Lee, JR; Injectable Biomimetic Hydrogel Constructs for Cell-Based Menopausal Hormone Therapy with Reduced Breast Cancer Potential Biomaterials research 2024-08-09 [PMID: 39135549] (Rat)		Rat
Lim, JJ;Vining, KH;Mooney, DJ;Blencowe, BJ; Matrix stiffness-dependent regulation of immunomodulatory genes in human MSCs is associated with the lncRNA CYTOR Proceedings of the National Academy of Sciences of the United States of America 2024-08-06 [PMID: 39074278] (Human)		Human
Liu, J;Yang, D;Sun, X;Yang, S;Zhang, Y;Li, Q;Deng, S;Dai, H;Wu, X; Mass spectrum oriented metabolomics for evaluating the efficacy and discovering the mechanism of Shaofuzhuyu Decoction for endometriosis of cold coagulation and blood stasis Heliyon 2024-07-15 [PMID: 39071582] (Rat)		Rat
Takacs, GP;Garcia, JS;Hodges, CA;Kreiger, CJ;Sherman, A;Harrison, JK; Glioma-derived M-CSF and IL-34 license M-MDSCs to suppress CD8+ T cells in a NOS-dependent manner bioRxiv : the preprint server for biology 2024-06-06 [PMID: 38895268] (Human)		Human
Luo, L;Wang, H;Xiong, J;Chen, X;Shen, X;Zhang, H; Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-?B and Keap1-Nrf2-HO-1 signaling pathways in macrophages PloS one 2024-05-16 [PMID: 38753858] (Mouse)		Mouse
Zhou, H;Zou, L;Ren, H;Shen, Z;Lin, Y;Cai, H;Zhang, J; Cathelicidin-BF regulates the AMPK/SIRT1/NF-?B pathway to ameliorate murine osteoarthritis: In vitro and in vivo studie International immunopharmacology 2024-05-07 [PMID: 38718660] (Mouse)		Mouse
Lokman, MS;Kassab, R;Salem, FAM;Elshopakey, GE;Hussein, A;Aldarmahi, AA;Theyab, A;Alzahrani, KJ;Hassan, KE;Alsharif, KF;Albrakati, A;Tayyeb, JZ;El-Khadragy, MF;Alkhateeb, MA;Al-Ghamdy, AO;Althagafi, HA;Abdel Moneim, A;El-Hennamy, RE; Asiatic acid rescues intestinal tissue by suppressing molecular, biochemical, and histopathological changes associated with the development of ulcerative colitis Bioscience reports 2024-05-05 [PMID: 38699907] (Rat)		Rat
Taibi, M;Elbouzidi, A;Haddou, M;Baraich, A;Loukili, EH;Moubchir, T;Allali, A;Amine Khoulati, ;Bellaouchi, R;Asehraou, A;Addi, M;Salamatullah, AM;Bourhia, M;Siddique, F;El Guerrouj, B;Chaabane, K; Phytochemical characterization and multifaceted bioactivity assessment of essential oil from Ptychotis verticillata Duby: Anti-diabetic, anti-tyrosinase, and anti-inflammatory activity Heliyon 2024-04-30 [PMID: 38699706] (Mouse)		Mouse
Lee, YM;Kim, DS; Analgesic, Anti-Inflammatory, and Chondroprotective Activities of Siraitia grosvenorii Residual Extract International journal of molecular sciences 2024-04-12 [PMID: 38673854] (Human)		Human
Kim, H;Jung, J;Lee, M;Kim, M;Kang, N;Kim, OK;Lee, J; Curcuma longa L. extract exhibits anti-inflammatory and cytoprotective functions in the articular cartilage of monoiodoacetate-injected rats Food & nutrition research 2024-03-19 [PMID: 38571919] (Rat)		Rat
Choi, YJ;Jung, JI;Bae, J;Lee, JK;Kim, EJ; Evaluating the Anti-Osteoarthritis Potential of Standardized Boswellia serrata Gum Resin Extract in Alleviating Knee Joint Pathology and Inflammation in Osteoarthritis-Induced Models International journal of molecular sciences 2024-03-12 [PMID: 38542192] (Rat)		Rat
Sun, J;Song, X;Wang, C;Ruan, Q; Geniposidic acid alleviates osteoarthritis progression through inhibiting inflammation and chondrocytes ferroptosis Journal of cellular and molecular medicine 2024-04-01 [PMID: 38520209] (Mouse)		Mouse
Ocampo, YC;Castro, JP;Pájaro, IB;Caro, D;Talero, E;Motilva, V;Franco, LA; Protective effect of sucrose esters from cape gooseberry (Physalis peruviana L.) in TNBS-induced colitis PloS one 2024-03-21 [PMID: 38512973] (Mouse)		Mouse
Jantaruk, P;Roytrakul, S;Sistayanarain, A;Kunthalert, D; The pomegranate-derived peptide Pug-4 alleviates nontypeable Haemophilus influenzae-induced inflammation by suppressing NF-kB signaling and NLRP3 inflammasome activation PeerJ 2024-02-20 [PMID: 38406294] (Human, Mouse)		Human, Mouse
Stachowicz-Suhs, M;?ab?d?, N;Anisiewicz, A;Banach, J;K?opotowska, D;Milczarek, M;Piotrowska, A;Dzi?giel, P;Maciejczyk, A;Matkowski, R;Wietrzyk, J; Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines Scientific reports 2024-02-15 [PMID: 38355711] (Mouse)		Mouse
Deng, C;Presle, N;Pizard, A;Guillaume, C;Bianchi, A;Kempf, H; Beneficial Impact of Eicosapentaenoic Acid on the Adverse Effects Induced by Palmitate and Hyperglycemia on Healthy Rat Chondrocyte International journal of molecular sciences 2024-02-02 [PMID: 38339087] (Rat)		Rat
Kim, J;Ryu, G;Seo, J;Go, M;Kim, G;Yi, S;Kim, S;Lee, H;Lee, JY;Kim, HS;Park, MC;Shin, DH;Shim, H;Kim, W;Lee, SY; 5-aminosalicylic acid suppresses osteoarthritis through the OSCAR-PPAR? axis Nature communications 2024-02-03 [PMID: 38310093] (Mouse)		Mouse
Liu, Z;Lee, H;Dong, L;Cheong, SH;Lee, DS; Fatsia japonica extract exerts antioxidant and anti-neuroinflammatory effects on neuronal cells and a zebrafish model Journal of ethnopharmacology 2024-01-26 [PMID: 38281691] (Mouse)		Mouse
Jayawardhana, HHACK;Liyanage, NM;Nagahawatta, DP;Lee, HG;Jeon, YJ;Kang, SI; Pepsin Hydrolysate from Surimi Industry-Related Olive Flounder Head Byproducts Attenuates LPS-Induced Inflammation and Oxidative Stress in RAW 264.7 Macrophages and In Vivo Zebrafish Model Marine drugs 2023-12-28 [PMID: 38248649] (Mouse)		Mouse
Chervet, A;Nehme, R;Decombat, C;Longechamp, L;Habanjar, O;Rousset, A;Fraisse, D;Blavignac, C;Filaire, E;Berthon, JY;Delort, L;Caldefie-Chezet, F; Exploring the Therapeutic Potential of Ampelopsis grossedentata Leaf Extract as an Anti-Inflammatory and Antioxidant Agent in Human Immune Cells International journal of molecular sciences 2023-12-28 [PMID: 38203587] (Human)		Human
Liu, G;Bae, KB;Yang, Y;Lee, BN;Hwang, YC; Icariin negatively regulated lipopolysaccharide-induced inflammation and ameliorated the odontogenic activity of human dental pulp cells in vitro Heliyon 2023-12-01 [PMID: 38144358] (Human)		Human
Hossain, MA;Lim, S;Bhilare, KD;Alam, MJ;Chen, B;Vijayakumar, A;Yoon, H;Kang, CW;Kim, JH; Bone marrow stem cells incubated with ellipticine regenerate articular cartilage by attenuating inflammation and cartilage degradation in rabbit model Journal of veterinary science 2023-11-01 [PMID: 38031520] (Rabbit)		Rabbit
Erdenebileg, S;Son, YJ;Kim, M;Oidovsambuu, S;Cha, KH;Kwon, J;Jung, DS;Nho, CW; Saposhnikovia divaricata root and its major components ameliorate inflammation and altered gut microbial diversity and compositions in DSS-induced colitis Integrative medicine research 2023-12-01 [PMID: 38024289] (Mouse)		Mouse
Jalilian, E;Abolhasani-Zadeh, F;Afgar, A;Samoudi, A;Zeinalynezhad, H;Langroudi, L; Neutralizing tumor-related inflammation and reprogramming of cancer-associated fibroblasts by Curcumin in breast cancer therapy Scientific reports 2023-11-26 [PMID: 38008819] (Human)		Human
Bi, W;Bao, K;Zhou, X;Deng, Y;Li, X;Zhang, J;Lan, X;Zhao, J;Lu, D;Xu, Y;Cen, Y;Cao, R;Xu, M;Zhong, W;Zhu, L; PSMC5 regulates microglial polarization and activation in LPS-induced cognitive deficits and motor impairments by interacting with TLR4 Journal of neuroinflammation 2023-11-24 [PMID: 38001534] (Mouse)		Mouse
Yan, Z;Wang, Y;Song, Y;Ma, Y;An, Y;Wen, R;Wang, N;Huang, Y;Wu, X; Phenethylferulate as a natural inhibitor of inflammation in LPS-stimulated RAW 264.7 macrophages: focus on NF-?B, Akt and MAPK signaling pathways BMC complementary medicine and therapies 2023-11-07 [PMID: 37936108] (Mouse)		Mouse
Park, JH;Kim, JH;Jang, SI;Cho, BO; Anti-inflammatory of disenecionyl cis-khellactone in LPS-stimulated RAW264.7 cells and the its inhibitory activity on soluble epoxide hydrolase Heliyon 2023-10-01 [PMID: 37876448] (Mouse)		Mouse
Beerts, C;Broeckx, SY;Depuydt, E;Tack, L;Van Hecke, L;Chiers, K;Van Brantegem, L;Braun, G;Hellmann, K;de Bouvre, N;Van Bruaene, N;De Ryck, T;Duchateau, L;Van Ryssen, B;Peremans, K;Saunders, JH;Verhoeven, G;Pauwelyn, G;Spaas, JH; Low-dose xenogeneic mesenchymal stem cells target canine osteoarthritis through systemic immunomodulation and homing Arthritis research & therapy 2023-10-03 [PMID: 37789403] (Canine)		Canine
Huh, G;Oh, Y;Jeon, Y;Kang, KS;Kim, SN;Jung, SH;Kim, SH;Kim, YJ; Insampaedok-San Extract Exerts an Immune-Enhancing Effect through NF-?B p65 Pathway Activation BioMed research international 2023-09-22 [PMID: 37780486] (Mouse)		Mouse
van Wigcheren, GF;Cuenca-Escalona, J;Stelloo, S;Brake, J;Peeters, E;Horrevorts, SK;Frölich, S;Ramos-Tomillero, I;Wesseling-Rozendaal, Y;van Herpen, CML;van de Stolpe, A;Vermeulen, M;de Vries, IJM;Figdor, CG;Flórez-Grau, G; Myeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways The Journal of biological chemistry 2023-09-20 [PMID: 37739035] (Human)		Human
Wu, Y;Ying, J;Zhu, X;Xu, C;Wu, L; Pachymic acid suppresses the inflammatory response of chondrocytes and alleviates the progression of osteoarthritis via regulating the Sirtuin 6/NF-?B signal axis International immunopharmacology 2023-08-30 [PMID: 37657246] (Mouse)		Mouse
Choi, S;Kim, S;Kim, K;Mony, T;Bae, H;Kim, M;Lee, C;Choi, S;Lee, S;Park, S; Fermented Sprouts of Codonopsis lanceolata Suppress LPS-Induced Inflammatory Responses by Inhibiting NF-kappa B Signaling Pathway in RAW 264.7 Macrophages and CD1 Mice Pharmaceutics 2023-01-01 [PMID: 37513980] (Mouse)		Mouse
Kim, HR;Lee, SH;Noh, EM;Choi, B;Seo, HY;Jang, H;Kim, SY;Park, MH; Therapeutic Effect of Enzymatically Hydrolyzed Cervi Cornu Collagen NP-2007 and Potential for Application in Osteoarthritis Treatment International journal of molecular sciences 2023-07-19 [PMID: 37511425] (Rat)		Rat
Liyanage, NM;Lee, HG;Nagahawatta, DP;Jayawardhana, HHACK;Song, KM;Choi, YS;Jeon, YJ;Kang, MC; Fucoidan from Sargassum autumnale Inhibits Potential Inflammatory Responses via NF-kappa B and MAPK Pathway Suppression in Lipopolysaccharide-Induced RAW 264.7 Macrophages Marine drugs 2023-06-25 [PMID: 37504905] (Mouse)		Mouse
Torre, E;Pinton, G;Lombardi, G;Fallarini, S; Melanoma Cells Inhibit iNKT Cell Functions via PGE2 and IDO1 Cancers 2023-07-05 [PMID: 37444608] (Human)		Human
Tanabe, N;Tomita, K;Manaka, S;Ichikawa, R;Takayama, T;Kawato, T;Ono, M;Masai, Y;Utsu, A;Suzuki, N;Sato, S; Co-Stimulation of AGEs and LPS Induces Inflammatory Mediators through PLC gamma 1/JNK/NF-kappa B Pathway in MC3T3-E1 Cells Cells 2023-05-13 [PMID: 37408216] (Mouse)		Mouse
Rahman, M;Upadhyay, S;Ganguly, K;Introna, M;Ji, J;Boman, C;Muala, A;Blomberg, A;Sandström, T;Palmberg, L; Comparable Response Following Exposure to Biodiesel and Diesel Exhaust Particles in Advanced Multicellular Human Lung Models Toxics 2023-06-14 [PMID: 37368632] (Human)		Human
Han, SJ;Lee, H;Nam, J;Pan, CH;Jeon, J;Yang, S; Schisandra extract ameliorates arthritis pathogenesis by suppressing the NF-?B and MAPK signalling pathways Journal of cellular and molecular medicine 2023-06-20 [PMID: 37337779] (Mouse)		Mouse
Lou, C;Lin, C;Wang, W;Jiang, H;Cai, T;Lin, S;Xue, X;Lin, J;Pan, X; Extracts of Oldenlandia diffusa protects chondrocytes via inhibiting apoptosis and associated inflammatory response in osteoarthritis Journal of ethnopharmacology 2023-06-07 [PMID: 37295574] (Mouse)		Mouse
Song, M;Qian, C;Zhang, T;Tang, Y;Zhou, Y;Wei, Z;Wang, A;Zhong, C;Zhao, Y;Lu, Y; Salvia mitiorrhiza Bunge aqueous extract attenuates infiltration of tumor-associated macrophages and potentiates anti-PD-L1 immunotherapy in colorectal cancer through modulating Cox2/PGE2 cascade Journal of ethnopharmacology 2023-06-05 [PMID: 37286115] (Xenograft)		Xenograft
Wang, C;Kim, IJ;Seong, HR;Noh, CH;Park, S;Kim, TM;Jeong, HS;Kim, KY;Kim, ST;Yuk, HG;Kwon, SC;Choi, EK;Kim, YB; Antioxidative and Anti-Inflammatory Activities of Rosebud Extracts of Newly Crossbred Roses Nutrients 2023-05-19 [PMID: 37242259] (Rat)		Rat
Kim, GO;Park, DH;Bae, JS; Protective Effects of Cirsilineol against Lipopolysaccharide-Induced Inflammation; Insights into HO-1, COX-2, and iNOS Modulation International journal of molecular sciences 2023-05-10 [PMID: 37239882] (Human)		Human
Zhang, P;Jin, Y;Xia, W;Wang, X;Zhou, Z; Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-?B axis and ameliorates osteoarthritis in mice Journal of orthopaedic translation 2023-07-01 [PMID: 37197096] (Mouse)		Mouse
Wang, Z;Ma, J;Miao, Z;Sun, Y;Dong, M;Lin, Y;Wu, Y;Sun, Z; Ergothioneine inhibits the progression of osteoarthritis via the Sirt6/NF-?B axis both in vitro and in vivo International immunopharmacology 2023-05-06 [PMID: 37156032] (Rat)		Rat
H Lee, Z Liu, L Dong, DY Lee, D Yoon, H Oh, YC Kim, RB An, DS Lee Anti-Neuroinflammatory and Neuroprotective Effect of Intermedin B Isolated from the Curcuma longa L. via NF-kappaB and ROS Inhibition in BV2 Microglia and HT22 Hippocampal Cells International Journal of Molecular Sciences, 2023-04-17;24(8):. 2023-04-17 [PMID: 37108568] (Mouse)		Mouse
KW Samarakoon, AI Kuruppu, JY Ko, JH Lee, YJ Jeon Structural Characterization and Anti-Inflammatory Effects of 24-Methylcholesta-5(6), 22-Diene-3beta-ol from the Cultured Marine Diatom Phaeodactylum tricornutum; Attenuate Inflammatory Signaling Pathways Marine Drugs, 2023-04-03;21(4):. 2023-04-03 [PMID: 37103370] (Mouse)		Mouse
SR Park, MG Kook, SR Kim, JW Lee, CH Park, BC Oh, Y Jung, IS Hong Development of cell-laden multimodular Lego-like customizable endometrial tissue assembly for successful tissue regeneration Biomaterials research, 2023-04-21;27(1):33. 2023-04-21 [PMID: 37085887] (Human)		Human
HR Lee, YJ Jeong, JW Lee, J Jhun, HS Na, KH Cho, SJ Kim, ML Cho, TH Heo Tannic acid, an IL-1beta-direct binding compound, ameliorates IL-1beta-induced inflammation and cartilage degradation by hindering IL-1beta-IL-1R1 interaction PLoS ONE, 2023-04-20;18(4):e0281834. 2023-04-20 [PMID: 37079558] (Human)		Human
HR Lee, YJ Jeong, JW Lee, J Jhun, HS Na, KH Cho, SJ Kim, ML Cho, TH Heo Tannic acid, an IL-1beta-direct binding compound, ameliorates IL-1beta-induced inflammation and cartilage degradation by hindering IL-1beta-IL-1R1 interaction PLoS ONE, 2023;18(4):e0281834. 2023 [PMID: 37079558] (Human)		Human
X Wang, D Wang, B Deng, L Yan Syringaresinol attenuates osteoarthritis via regulating the NF-kappaB pathway International immunopharmacology, 2023-03-28;118(0):109982. 2023-03-28 [PMID: 36989902] (Mouse)		Mouse
E Kuca-Warna, W Kurowska, M Pleba?czyk, A Wajda, A Kornatka, T Burakowski, I Janicka, P Syrówka, U Skalska Basic Properties of Adipose-Derived Mesenchymal Stem Cells of Rheumatoid Arthritis and Osteoarthritis Patients Pharmaceutics, 2023-03-20;15(3):. 2023-03-20 [PMID: 36986863] (Human)		Human
JH Park, JH Kim, JY Shin, ES Kang, BO Cho Anti-inflammatory effects of Peucedanum japonicum Thunberg leaves extract in Lipopolysaccharide-stimulated RAW264.7�cells Journal of ethnopharmacology, 2023-03-10;309(0):116362. 2023-03-10 [PMID: 36907479] (Mouse)		Mouse
EA Ross, LA Turner, H Donnelly, A Saeed, MP Tsimbouri, KV Burgess, G Blackburn, V Jayawarna, Y Xiao, MAG Oliva, J Willis, J Bansal, P Reynolds, JA Wells, J Mountford, M Vassalli, N Gadegaard, ROC Oreffo, M Salmeron-S, MJ Dalby Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells Nature Communications, 2023-02-10;14(1):753. 2023-02-10 [PMID: 36765065] (Human)		Human
J Cholet, C Decombat, L Delort, M Gainche, A Berry, C Ogeron, I Ripoche, M Vareille-D, M Vermerie, D Fraisse, C Felgines, A Rossary, E Ranouille, JY Berthon, A Tourrette, J Priam, E Saunier, Y Troin, F Senejoux, P Chalard, F Caldefie-C Potential Anti-Inflammatory and Chondroprotective Effect of Luzula sylvatica International Journal of Molecular Sciences, 2022-12-21;24(1):. 2022-12-21 [PMID: 36613576] (Human)		Human
S Lin, J Lu, Q Chen, H Jiang, C Lou, C Lin, W Wang, J Lin, X Pan, X Xue Plantamajoside suppresses the activation of NF-kappaB and MAPK and ameliorates the development of osteoarthritis International immunopharmacology, 2022-12-28;115(0):109582. 2022-12-28 [PMID: 36584575] (Mouse)		Mouse
ZH Al-Oanzi, FO Alenazy, HH Alhassan, MR El-Aassar, AI Alzarea, SI Alzarea, AM Abbas, MH Alanazi, MM Al-Enazi Effects of Thymoquinone Alone or in Combination with Losartan on the Cardiotoxicity Caused by Oxidative Stress and Inflammation in Hypercholesterolemia Journal of cardiovascular development and disease, 2022-12-01;9(12):. 2022-12-01 [PMID: 36547425] (Rat)		Rat
R Jeske, X Chen, S Ma, EZ Zeng, T Driscoll, Y Li Bioreactor Expansion Reconfigures Metabolism and Extracellular Vesicle Biogenesis of Human Adipose-derived Stem Cells In Vitro Biochemical engineering journal, 2022-11-02;188(0):. 2022-11-02 [PMID: 36540623] (Human)		Human
J Wu, H Li, F Hu, P Luo Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-kappaB pathway Journal of Orthopaedic Translation, 2022-11-15;38(0):190-202. 2022-11-15 [PMID: 36439628] (Mouse)		Mouse
EL Ngu, CY Tan, NJ Lai, KH Wong, SH Lim, LC Ming, KO Tan, SM Phang, YY Yow Spirulina platensis Suppressed iNOS and Proinflammatory Cytokines in Lipopolysaccharide-Induced BV2 Microglia Metabolites, 2022-11-20;12(11):. 2022-11-20 [PMID: 36422287] (Mouse)		Mouse
B Li, M Wang, S Chen, M Li, J Zeng, S Wu, Y Tu, Y Li, R Zhang, F Huang, X Tong Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF-kappaB and MAPK Pathways in LPS-Stimulated BV-2 Microglia BioMed Research International, 2022-11-09;2022(0):3263446. 2022-11-09 [PMID: 36408278] (Mouse)		Mouse
C Jia, F Hu, D Lu, H Jin, H Lu, E Xue, D Wu Formononetin inhibits IL-1beta-induced inflammation in human chondrocytes and slows the progression of osteoarthritis in rat model via the regulation of PTEN/AKT/NF-kappaB pathway International immunopharmacology, 2022-10-25;113(0):109309. 2022-10-25 [PMID: 36306560] (Human, Rat)		Human, Rat
SA El Kazafy, YM Fouad, AF Said, HH Assal, TM Ali, AE Ahmed, BH Elesawy, OM Ahmed Correlations between Cytokine Levels, Liver Function Markers, and Neuropilin-1 Expression in Patients with COVID-19 Vaccines, 2022-09-29;10(10):. 2022-09-29 [PMID: 36298501] (Human)		Human
Y Wu, M Liu, H Zhou, X He, W Shi, Q Yuan, Y Zuo, B Li, Q Hu, Y Xie COX-2/PGE2/VEGF signaling promotes ERK-mediated BMSCs osteogenic differentiation under hypoxia by the paracrine action of ECs Cytokine, 2022-10-07;161(0):156058. 2022-10-07 [PMID: 36209650] (Rat)		Rat
A Hasan, S Devi Ms, G Sharma, V Narayanan, P Sathiyaraj, S Vinayak, S Sunil Vathasura Kudineer, an Andrographis based polyherbal formulation exhibits immunomodulation and inhibits chikungunya virus (CHIKV) under in-vitro conditions Journal of ethnopharmacology, 2022-09-29;0(0):115762. 2022-09-29 [PMID: 36181982] (Mouse)		Mouse
N Kim, C Kim, SH Ryu, GO Kim, JS Bae Anti-Inflammatory Effect of Sparstolonin B through Inhibiting Expression of NF-kappaB and STAT-1 International Journal of Molecular Sciences, 2022-09-06;23(18):. 2022-09-06 [PMID: 36142124] (Human)		Human
GA Estúa-Acos, B Buentello-, FS Magaña-Gue, JE Flores, O Vivanco-Ro, I Castro-Sal, K Zarco-Ávil, MA García-Mej, Y Garfias Human Amniotic Membrane Mesenchymal Stem Cell-Synthesized PGE2 Exerts an Immunomodulatory Effect on Neutrophil Extracellular Trap in a PAD-4-Dependent Pathway through EP2 and EP4 Cells, 2022-09-10;11(18):. 2022-09-10 [PMID: 36139406] (Human)		Human
MS Piccinno, T Petrachi, M Pignatti, A Murgia, G Grisendi, O Candini, E Resca, V Bergamini, F Ganzerli, A Portone, I Mastrolia, C Chiavelli, I Castelli, D Bernabei, M Tagliazucc, E Bonetti, F Lolli, G De Santis, M Dominici, E Veronesi Human Adipose Mesenchymal Stromal/Stem Cells Improve Fat Transplantation Performance Cells, 2022-09-07;11(18):. 2022-09-07 [PMID: 36139372] (Xenograft)		Xenograft
Y Mu, L Wang, L Fu, Q Li Knockdown of LMX1B Suppressed Cell Apoptosis and Inflammatory Response in IL-1beta-Induced Human Osteoarthritis Chondrocytes through NF-kappaB and NLRP3 Signal Pathway Mediators of Inflammation, 2022-09-12;2022(0):1870579. 2022-09-12 [PMID: 36133743] (Human)		Human
Q Sun, Y Zhang, Y Ding, W Xie, H Li, S Li, Y Li, M Cai Inhibition of PGE2 in Subchondral Bone Attenuates Osteoarthritis Cells, 2022-09-05;11(17):. 2022-09-05 [PMID: 36078169] (Mouse)		Mouse
M Wu, C Ye, H Li, X Yang, S Zhu, F Zhou, Y Hao, S Chen, S Jiang A Nested Case-Control Study of the Relationship between Salivary Inflammatory Mediators, Periodontal Parameters, and Preterm Birth in a Chinese Population BioMed Research International, 2022-08-18;2022(0):8629680. 2022-08-18 [PMID: 36033560] (Human)		Human
J Rodríguez-, JM Torres-Are, N Ávila-Vanz, R Springall, R Bojalil, O Infante, C Lerma, JC Echeverría Association of the Heart Rate Variability Response to Active Standing with the Severity of Calcific Aortic Valve Disease: Novel Insights of a Neurocardiovascular Pathology Journal of Clinical Medicine, 2022-08-16;11(16):. 2022-08-16 [PMID: 36013009] (Human)		Human
HJ Lee, CH Yoon, HJ Kim, JH Ko, JS Ryu, DH Jo, JH Kim, D Kim, JY Oh Ocular microbiota promotes pathological angiogenesis and inflammation in sterile injury-driven corneal neovascularization Mucosal Immunology, 2022-08-19;0(0):. 2022-08-19 [PMID: 35986099] (Mouse)		Mouse
S Li, Y Shi, S Zhang, H Li, Z Ye, J Kong, W Hong, Y Tu, J Ren, Z Meftah, C Xie, X Wang, X Zhang Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-kappaB Pathway Oxidative Medicine and Cellular Longevity, 2022-07-28;2022(0):2188145. 2022-07-28 [PMID: 35941903] (Mouse)		Mouse
EH Lim, SK Mun, JJ Kim, DJ Chang, ST Yee Anti-Inflammatory Effects of Phlebia sp. Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages BioMed Research International, 2022-07-14;2022(0):2717196. 2022-07-14 [PMID: 35872858] (Mouse)		Mouse
J Zhang, H Zhang, X Ding, J Hu, Y Li, J Zhang, H Wang, S Qi, A Xie, J Shi, M Xiang, Y Bin, G Wang, L Wang, Z Wang Crosstalk between macrophage-derived PGE2 and tumor UHRF1 drives hepatocellular carcinoma progression Theranostics, 2022-05-01;12(8):3776-3793. 2022-05-01 [PMID: 35664070] (Human)		Human
Z Barcikowsk, ME Grzybowska, P W??, M Jaskulak, M Kurpas, M Sotomski, M Starzec-Pr, E Rajkowska-, R Hansdorfer, K Zorena Effect of Manual Therapy Compared to Ibuprofen on Primary Dysmenorrhea in Young Women-Concentration Assessment of C-Reactive Protein, Vascular Endothelial Growth Factor, Prostaglandins and Sex Hormones Journal of Clinical Medicine, 2022-05-10;11(10):. 2022-05-10 [PMID: 35628817] (Human)		Human
T Genovese, M Cordaro, R Siracusa, D Impellizze, S Caudullo, E Raffone, F Macrí, L Interdonat, E Gugliandol, C Interlandi, R Crupi, R D'Amico, R Fusco, S Cuzzocrea, R Di Paola Molecular and Biochemical Mechanism of Cannabidiol in the Management of the Inflammatory and Oxidative Processes Associated with Endometriosis International Journal of Molecular Sciences, 2022-05-12;23(10):. 2022-05-12 [PMID: 35628240] (Rat)		Rat
ME Kotas, CM Moore, JG Gurrola, SD Pletcher, AN Goldberg, R Alvarez, S Yamato, PE Bratcher, CA Shaughness, PL Zeitlin, IH Zhang, Y Li, MT Montgomery, K Lee, EK Cope, RM Locksley, MA Seibold, ED Gordon IL-13-programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function JCI Insight, 2022-07-08;7(13):. 2022-07-08 [PMID: 35608904] (Mouse)		Mouse
WJ Ho, JNP Smith, YS Park, M Hadiono, K Christo, A Jogasuria, Y Zhang, AV Broncano, L Kasturi, DM Dawson, SL Gerson, SD Markowitz, AB Desai 15-PGDH regulates hematopoietic and gastrointestinal fitness during aging PLoS ONE, 2022-05-19;17(5):e0268787. 2022-05-19 [PMID: 35587945] (Mouse)		Mouse
R Boi, K Ebefors, M Henricsson, J Borén, J Nyström Modified lipid metabolism and cytosolic phospholipase A2 activation in mesangial cells under pro-inflammatory conditions Scientific Reports, 2022-05-05;12(1):7322. 2022-05-05 [PMID: 35513427] (Human)		Human
T Genovese, D Impellizze, R D'Amico, M Cordaro, AF Peritore, R Crupi, E Gugliandol, S Cuzzocrea, R Fusco, R Siracusa, R Di Paola Resveratrol Inhibition of the WNT/beta-Catenin Pathway following Discogenic Low Back Pain International Journal of Molecular Sciences, 2022-04-07;23(8):. 2022-04-07 [PMID: 35456908] (Human)		Human
M Yang, Z Yang, Y Li, S Su, Z Li, D Lu Mechanism of Traditional Tibetan Medicine Grubthobrildkr Alleviated Gastric Ulcer Induced by Acute Systemic Hypoxia in Rats BioMed Research International, 2022-04-05;2022(0):4803956. 2022-04-05 [PMID: 35425842] (Rat)		Rat
P Arora, W Li, X Huang, W Yu, R Huang, Q Jiang, C Chen Metabolic Reconfiguration Activates Stemness and Immunomodulation of PDLSCs International Journal of Molecular Sciences, 2022-04-06;23(7):. 2022-04-06 [PMID: 35409397] (Human)		Human
Q Zhao, W Dai, HY Chen, RE Jacobs, BV Zlokovic, BT Lund, A Montagne, A Bonnin Prenatal disruption of blood-brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation Proceedings of the National Academy of Sciences of the United States of America, 2022-04-04;119(15):e2113310119. 2022-04-04 [PMID: 35377817] (Mouse)		Mouse
Y Xin, H Ji, E Cho, KB Roh, J You, D Park, E Jung Immune-enhancing effect of water-soluble beta-glucan derived from enzymatic hydrolysis of yeast glucan Biochemistry and Biophysics Reports, 2022-03-27;30(0):101256. 2022-03-27 [PMID: 35368741] (Mouse)		Mouse
X Gao, X Kang, H Lu, E Xue, R Chen, J Pan, J Ma Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis?fibroblast?like synoviocytes by inhibiting the NF?kappaB and MAPK signaling pathways Molecular Medicine Reports, 2022-03-24;25(5):. 2022-03-24 [PMID: 35322865] (Rat)		Rat
Y Yuan, Q Hu, L Liu, F Xie, L Yang, Y Li, C Zhang, H Chen, J Tang, X Shen Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKalpha/beta-NF-kappaB and Keap1-Nrf2 Signalling Pathways Frontiers in Pharmacology, 2022-03-07;13(0):817596. 2022-03-07 [PMID: 35321327] (Mouse)		Mouse
JH Cai, YT Sun, S Bao HucMSCs-exosomes containing miR-21 promoted estrogen production in ovarian granulosa cells via LATS1-mediated phosphorylation of LOXL2 and YAP General and comparative endocrinology, 2022-03-07;0(0):114015. 2022-03-07 [PMID: 35271888] (Human)		Human
J Hernandez-, N Abasolo, H Palacios-J, E Foguet-Rom, D Suñol, M Galofré, A Caimari, L Baselga-Es, JM Del Bas, M Mulero Imbalances in TCA, Short Fatty Acids and One-Carbon Metabolisms as Important Features of Homeostatic Disruption Evidenced by a Multi-Omics Integrative Approach of LPS-Induced Chronic Inflammation in Male Wistar Rats International Journal of Molecular Sciences, 2022-02-25;23(5):. 2022-02-25 [PMID: 35269702] (Rat)		Rat
HC Kuo, KF Lee, SL Chen, SC Chiu, LY Lee, WP Chen, CC Chen, CH Chu Neuron-Microglia Contacts Govern the PGE2 Tolerance through TLR4-Mediated de Novo Protein Synthesis Biomedicines, 2022-02-10;10(2):. 2022-02-10 [PMID: 35203628] (Mouse)		Mouse
Z Zhou, L Zhang, Y Liu, C Huang, W Xia, H Zhou, Z Zhou, X Zhou Luteolin Protects Chondrocytes from H2O2-Induced Oxidative Injury and Attenuates Osteoarthritis Progression by Activating AMPK-Nrf2 Signaling Oxidative Medicine and Cellular Longevity, 2022-02-01;2022(0):5635797. 2022-02-01 [PMID: 35154568] (Mouse)		Mouse
E Kuca-Warna, M Olesi?ska, P Szcz?sny, E Kontny Impact and Possible Mechanism(s) of Adipose Tissue-Derived Mesenchymal Stem Cells on T-Cell Proliferation in Patients With Rheumatic Disease Frontiers in Physiology, 2022-01-13;12(0):749481. 2022-01-13 [PMID: 35095547] (Human)		Human
A Gallo, N Cuscino, F Contino, M Bulati, M Pampalone, G Amico, G Zito, C Carcione, C Centi, A Bertani, PG Conaldi, V Miceli Changes in the Transcriptome Profiles of Human Amnion-Derived Mesenchymal Stromal/Stem Cells Induced by Three-Dimensional Culture: A Potential Priming Strategy to Improve Their Properties International Journal of Molecular Sciences, 2022-01-13;23(2):. 2022-01-13 [PMID: 35055049] (Human)		Human
D Lee, H Jo, C Go, Y Jang, N Chu, S Bae, D Kang, Y Kim, JS Kang The Roles of IL-22 and Its Receptor in the Regulation of Inflammatory Responses in the Brain International Journal of Molecular Sciences, 2022-01-11;23(2):. 2022-01-11 [PMID: 35054942] (Mouse)		Mouse
JJ Tang, LF Huang, JL Deng, YM Wang, C Guo, XN Peng, Z Liu, JM Gao Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model Redox Biology, 2022-01-08;50(0):102229. 2022-01-08 [PMID: 35026701] (Mouse)		Mouse
SW Shin, YS Hwang Anti-Periodontitis Effect of Ethanol Extracts of Alpinia Katsumadai Seeds Nutrients, 2021-12-28;14(1):. 2021-12-28 [PMID: 35011011] (Human)		Human
KM Kim, SY Kim, TJ Mony, HJ Bae, SD Han, ES Lee, SH Choi, SH Hong, SD Lee, SJ Park Dracocephalum moldavica Ethanol Extract Suppresses LPS-Induced Inflammatory Responses through Inhibition of the JNK/ERK/NF-kappaB Signaling Pathway and IL-6 Production in RAW 264.7 Macrophages and in Endotoxic-Treated Mice Nutrients, 2021-12-16;13(12):. 2021-12-16 [PMID: 34960054] (Mouse)		Mouse
A Stemmler, J Symmank, J Steinmetz, K von Brande, CL Hennig, C Jacobs GDF15 Supports the Inflammatory Response of PdL Fibroblasts Stimulated by P. gingivalis LPS and Concurrent Compression International Journal of Molecular Sciences, 2021-12-19;22(24):. 2021-12-19 [PMID: 34948405] (Human)		Human
X Hu, YA Zhang, B Chen, Z Jin, ML Lin, M Li, HX Mei, JC Lu, YQ Gong, SW Jin, SX Zheng Protectin DX promotes the inflammatory resolution via activating COX-2/L-PGDS-PGD2 and DP1 receptor in acute respiratory distress syndrome International immunopharmacology, 2021-11-10;102(0):108348. 2021-11-10 [PMID: 34920958] (Rat)		Rat
R Shvartsur, G Agam, A Shnaider, S Uzzan, A Nassar, A Jabarin, N Abu-Freha, K Meir, AN Azab Safety and Efficacy of Combined Low-Dose Lithium and Low-Dose Aspirin: A Pharmacological and Behavioral Proof-of-Concept Study in Rats Pharmaceutics, 2021-11-01;13(11):. 2021-11-01 [PMID: 34834241] (Rat)		Rat
RH Mohamed, A Khalphalla, K Nakada, E Elmeligy, D Hassan, EA Ebissy, RA Ghandour, SA Mousa, ASA Hassaneen Clinical and Correlated Responses among Steroid Hormones and Oxidant/Antioxidant Biomarkers in Pregnant, Non-Pregnant and Lactating CIDR-Pre-Synchronized Dromedaries (Camelus dromedarius) Veterinary sciences, 2021-10-21;8(11):. 2021-10-21 [PMID: 34822620] (Camel)		Camel
CH Lee, CF Chiang, FC Kuo, SC Su, CL Huang, JS Liu, CH Lu, CH Hsieh, CC Wang, CH Lee, PH Shen High-Molecular-Weight Hyaluronic Acid Inhibits IL-1beta-Induced Synovial Inflammation and Macrophage Polarization through the GRP78-NF-kappaB Signaling Pathway International Journal of Molecular Sciences, 2021-11-03;22(21):. 2021-11-03 [PMID: 34769349] (Human)		Human
H Mohammadpo, CR MacDonald, PL McCarthy, SI Abrams, EA Repasky beta2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME Cell Reports, 2021-10-26;37(4):109883. 2021-10-26 [PMID: 34706232] (Human, Mouse)		Human, Mouse
MR Shin, JH Lee, JA Lee, MJ Kim, HJ Park, BW Park, SB Seo, SS Roh Immunomodulatory and anti-inflammatory effects of Phellinus linteus mycelium BMC complementary medicine and therapies, 2021-10-26;21(1):269. 2021-10-26 [PMID: 34702240] (Human)		Human
G Jang, S Lee, J Hong, B Park, D Kim, C Kim Anti-Inflammatory Effect of 4,5-Dicaffeoylquinic Acid on RAW264.7 Cells and a Rat Model of Inflammation Nutrients, 2021-10-09;13(10):. 2021-10-09 [PMID: 34684537] (Mouse)		Mouse
E Pape, M Parent, A Pinzano, A Sapin-Mine, C Henrionnet, P Gillet, J Scala-Bert, N Gambier Rapamycin-loaded Poly(lactic-co-glycolic) acid nanoparticles: Preparation, characterization, and in vitro toxicity study for potential intra-articular injection International journal of pharmaceutics, 2021-10-16;609(0):121198. 2021-10-16 [PMID: 34662644] (Human)		Human
Y Wang, H Zhang, M Wang, J He, H Guo, L Li, J Wang CCNB2/SASP/Cathepsin B & PGE2 Axis Induce Cell Senescence Mediated Malignant Transformation International journal of biological sciences, 2021-08-13;17(13):3538-3553. 2021-08-13 [PMID: 34512164] (Human)		Human
L Dai, Q Wang, X Lv, F Gao, Z Chen, Y Shen Elevated beta-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease Brain, Behavior, and Immunity, 2021-09-06;98(0):337-348. 2021-09-06 [PMID: 34500034] (Mouse)		Mouse
J Cheng, Z Xie, S Wang, S Wen, S Niu, C Shi, L Yu, X Xu Cough hypersensitivity in patients with metabolic syndrome: a clinical finding and its possible mechanisms BMC pulmonary medicine, 2021-09-06;21(1):284. 2021-09-06 [PMID: 34488706] (Human)		Human
S Liu, Q Wang, Z Li, L Ma, T Li, Y Li, N Wang, C Liu, P Xue, C Wang TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration Oxidative Medicine and Cellular Longevity, 2021-08-21;2021(0):9965737. 2021-08-21 [PMID: 34471470] (Mouse)		Mouse
JJ Shi, HF Liu, T Hu, X Gao, YB Zhang, WR Li, Q Wang, SJ Zhang, D Tang, YB Chen Danggui-Shaoyao-San improves cognitive impairment through inhibiting O-GlcNAc-modification of estrogen alpha receptor in female db/db mice Journal of ethnopharmacology, 2021-08-23;281(0):114562. 2021-08-23 [PMID: 34438027] (Mouse)		Mouse
JJ Tang, MR Wang, S Dong, LF Huang, QR He, JM Gao 1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-kappaB/MAPK pathways European Journal of Medicinal Chemistry, 2021-07-21;224(0):113713. 2021-07-21 [PMID: 34315042] (Mouse)		Mouse
H Lee, Z Liu, CS Yoon, L Dong, W Ko, ER Woo, DS Lee Anti-Neuroinflammatory and Anti-Inflammatory Activities of Phenylheptatriyne Isolated from the Flowers of Coreopsis lanceolata L. via NF-kappaB Inhibition and HO-1 Expression in BV2 and RAW264.7 Cells International Journal of Molecular Sciences, 2021-07-13;22(14):. 2021-07-13 [PMID: 34299102] (Mouse)		Mouse
P Zhu, Z Wang, Z Sun, B Liao, Y Cai Recombinant platelet-derived growth factor-BB alleviates osteoarthritis in a rat model by decreasing chondrocyte apoptosis in vitro and in vivo Journal of Cellular and Molecular Medicine, 2021-07-11;0(0):. 2021-07-11 [PMID: 34250725] (Rat)		Rat
C Park, H Lee, S Hong, IMN Molagoda, JW Jeong, CY Jin, GY Kim, SH Choi, SH Hong, YH Choi Inhibition of Lipopolysaccharide-Induced Inflammatory and Oxidative Responses by Trans-cinnamaldehyde in C2C12 Myoblasts International Journal of Medical Sciences, 2021-04-23;18(12):2480-2492. 2021-04-23 [PMID: 34104079] (Human)		Human
HJ Kim, YJ Kim, W Park Berberine modulates hyper-inflammation in mouse macrophages stimulated with polyinosinic-polycytidylic acid via calcium-CHOP/STAT pathway Scientific Reports, 2021-05-28;11(1):11298. 2021-05-28 [PMID: 34050236] (Mouse)		Mouse
BO Cho, JY Shin, HJ Kang, JH Park, S Hao, F Wang, SI Jang Anti?inflammatory effect of Chrysanthemum zawadskii, peppermint, Glycyrrhiza glabra herbal mixture in�lipopolysaccharide?stimulated RAW264.7 macrophages Molecular Medicine Reports, 2021-05-26;24(1):. 2021-05-26 [PMID: 34036392] (Mouse)		Mouse
K Battiston, I Parrag, M Statham, D Louka, H Fischer, G Mackey, A Daley, F Gu, E Baldwin, B Yang, B Muirhead, EA Hicks, H Sheardown, L Kalachev, C Crean, J Edelman, JP Santerre, W Naimark Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery Nature Communications, 2021-05-17;12(1):2875. 2021-05-17 [PMID: 34001908] (Human)		Human
R Jeske, S Lewis, AC Tsai, K Sanders, C Liu, X Yuan, Y Li Agitation in a Microcarrier-based Spinner Flask Bioreactor Modulates Homeostasis of Human Mesenchymal Stem Cells Biochemical engineering journal, 2021-01-27;168(0):. 2021-01-27 [PMID: 33967591] (Human)		Human
Y Yan, H Zou, X Lian, L Yang Cyclic mechanical stimulation inhibits rheumatoid arthritis fibroblast-like synoviocytes proliferation via cell cycle arrest Journal of biomechanics, 2021-04-08;121(0):110424. 2021-04-08 [PMID: 33873113] (Human)		Human
YK Ji, SM Lee, NH Kim, NV Tu, YN Kim, JD Heo, EJ Jeong, JR Rho Stereochemical Determination of Fistularins Isolated from the Marine Sponge Ecionemia acervus and Their Regulatory Effect on Intestinal Inflammation Marine Drugs, 2021-03-22;19(3):. 2021-03-22 [PMID: 33809895] (Human)		Human
E Park, CG Lee, SJ Han, SH Yun, S Hwang, H Jeon, J Kim, CW Choi, S Yang, SY Jeong Antiosteoarthritic Effect of Morroniside in Chondrocyte Inflammation and Destabilization of Medial Meniscus-Induced Mouse Model International Journal of Molecular Sciences, 2021-03-15;22(6):. 2021-03-15 [PMID: 33804203] (Mouse)		Mouse
L Bertoni, S Jacquet-Gu, T Branly, M Desancé, F Legendre, M Melin, P Rivory, DJ Hartmann, A Schmutz, JM Denoix, M Demoor, F Audigié, P Galéra Evaluation of Allogeneic Bone-Marrow-Derived and Umbilical Cord Blood-Derived Mesenchymal Stem Cells to Prevent the Development of Osteoarthritis in An Equine Model International Journal of Molecular Sciences, 2021-03-02;22(5):. 2021-03-02 [PMID: 33801461] (Equine)		Equine
S Gonçalves, K Yin, Y Ito, A Chan, I Olan, S Gough, L Cassidy, E Serrao, S Smith, A Young, M Narita, M Hoare COX2 regulates senescence secretome composition and senescence surveillance through PGE2 Cell Reports, 2021-03-16;34(11):108860. 2021-03-16 [PMID: 33730589] (Human)		Human
N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation Nature Communications, 2021-02-22;12(1):1209. 2021-02-22 [PMID: 33619282] (Human)		Human
P Filannino, R Di Cagno, O Vincentini, D Pinto, A Polo, F Maialetti, A Porrelli, M Gobbetti Nutrients Bioaccessibility and Anti-inflammatory Features of Fermented Bee Pollen: A Comprehensive Investigation Frontiers in Microbiology, 2021-02-02;12(0):622091. 2021-02-02 [PMID: 33603725] (Human)		Human
R Xing, J Yang, R Wang, Y Wang Extracorporeal shock wave therapy for treating primary dysmenorrhea: A randomized controlled trial Medicine, 2021-02-05;100(5):e23798. 2021-02-05 [PMID: 33592837] (Human)		Human
YN Kim, YK Ji, NH Kim, N Van Tu, JR Rho, EJ Jeong Isoquinolinequinone Derivatives from a Marine Sponge (Haliclona sp.) Regulate Inflammation in In Vitro System of Intestine Marine Drugs, 2021-02-04;19(2):. 2021-02-04 [PMID: 33557170] (Human)		Human
CY Chang, CC Wu, JD Wang, JR Li, YY Wang, SY Lin, WY Chen, SL Liao, CJ Chen DHA attenuated Japanese Encephalitis virus infection-induced neuroinflammation and neuronal cell death in cultured rat Neuron/glia Brain, Behavior, and Immunity, 2021-01-21;0(0):. 2021-01-21 [PMID: 33486004] (Rat)		Rat
I Pountos, M Panteli, G Walters, PV Giannoudis NSAIDs inhibit bone healing through the downregulation of TGF-&beta3 expression during endochondral ossification Injury, 2021-01-10;0(0):. 2021-01-10 [PMID: 33472741] (Human)		Human
GY Min, JM Park, IH Joo, DH Kim Inhibition effect of Caragana sinica root extracts on Osteoarthritis through MAPKs, NF-&kappaB signaling pathway International Journal of Medical Sciences, 2021-01-01;18(4):861-872. 2021-01-01 [PMID: 33456343] (Rat)		Rat
A Dorronsoro, V Lang, I Ferrin, J Fernández-, L Zabaleta, E Pérez-Ruiz, P Sepúlveda, C Trigueros Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation Scientific Reports, 2020-12-14;10(1):21853. 2020-12-14 [PMID: 33318571] (Human)		Human
MFA Mohamed, AA Marzouk, A Nafady, DA El-Gamal, RM Allam, GEA Abuo-Rahma, HI El Subbagh, AH Moustafa Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors Bioorg Chem, 2020-10-28;105(0):104439. 2020-10-28 [PMID: 33161252] (Mouse)		Mouse
L Jia, K Xue, J Liu, OA Habotta, L Hu, AE Abdel Mone Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways Mediators Inflamm, 2020-09-29;2020(0):9419085. 2020-09-29 [PMID: 33061833] (Rat)		Rat
YJ Park, SY Cheon, DS Lee, DC Cominguez, Z Zhang, S Lee, HJ An Anti-Inflammatory and Antioxidant Effects of Carpesium cernuum L. Methanolic Extract in LPS-Stimulated RAW 264.7 Macrophages Mediators Inflamm., 2020-08-07;2020(0):3164239. 2020-08-07 [PMID: 32848508] (Mouse)		Mouse
C Salgado, L Guénée, R ?erný, E Allémann, O Jordan Nano wet milled celecoxib extended release microparticles for local management of chronic inflammation Int J Pharm, 2020-08-19;589(0):119783. 2020-08-19 [PMID: 32827674] (Bioassay, Human)	Bioassay	Human
G Rosa, AMT Krieck, E Padula, JPH Pfeifer, JB de Souza, M Rossi, F Stievani, E Deffune, R Takahira, ALG Alves Allogeneic synovial membrane-derived mesenchymal stem cells do not significantly affect initial inflammatory parameters in a LPS-induced acute synovitis model Res. Vet. Sci., 2020-08-08;132(0):485-491. 2020-08-08 [PMID: 32799173] (Equine)		Equine
B Chen, Q Chai, S Xu, Q Li, T Wu, S Chen, L Wu Silver nanoparticle-activated COX2/PGE2 axis involves alteration of lung cellular senescence in vitro and in vivo Ecotoxicol. Environ. Saf., 2020-08-04;204(0):111070. 2020-08-04 [PMID: 32763567] (Human)		Human
MA Haque, I Jantan, H Harikrishn, W Ahmad Standardized ethanol extract of Tinospora crispa upregulates pro-inflammatory mediators release in LPS-primed U937 human macrophages through stimulation of MAPK, NF-kappaB and PI3K-Akt signaling networks BMC Complement Med Ther, 2020-08-06;20(1):245. 2020-08-06 [PMID: 32762741] (Human, Tinospora crispa)		Human, Tinospora crispa
R Liu, H Wu, H Song Knockdown of TRIM8 Attenuates IL-1beta-induced Inflammatory Response in Osteoarthritis Chondrocytes Through the Inactivation of NF-kappaB Pathway Cell Transplant, 2020-01-01;29(0):9636897209436. 2020-01-01 [PMID: 32757662] (Human)		Human
ES Son, JW Park, SH Kim, HR Park, W Han, OC Kwon, JY Nam, SH Jeong, CS Lee Anti?inflammatory activity of 3,5,6,7,3',4'?hexamethoxyflavone via repression of the NF?&kappaB and MAPK signaling pathways in LPS?stimulated RAW264.7 cells Mol Med Rep, 2020-06-18;22(3):1985-1993. 2020-06-18 [PMID: 32705181] (Mouse)		Mouse
T Park, JS Park, JH Sim, SY Kim 7-Acetoxycoumarin Inhibits LPS-Induced Inflammatory Cytokine Synthesis by I&kappaB&alpha Degradation and MAPK Activation in Macrophage Cells Molecules, 2020-07-08;25(14):. 2020-07-08 [PMID: 32650550] (Mouse)		Mouse
KS Lee, E Cho, JB Weon, D Park, M Fréchet, H Chajra, E Jung Inhibition of UVB-Induced Inflammation by Laminaria japonica Extract via Regulation of nc886-PKR Pathway Nutrients, 2020-06-30;12(7):. 2020-06-30 [PMID: 32630038] (Human)		Human
M Hecker, M Rose, A Hecker, H Dietrich, MB Schaefer, N Sommer, W Seeger, K Mayer Immunomodulation by an Omega-6 Fatty Acid Reduced Mixed Lipid Emulsion in Murine Acute Respiratory Distress Syndrome J Clin Med, 2020-06-29;9(7):. 2020-06-29 [PMID: 32610690] (Mouse)		Mouse
Y Zhao, K He, H Zheng, M Sun, T Shi, X Zheng, D Shao, H Zhang, F Guan, J Li, L Chen Berberine Inhibits the Apoptosis-Induced Metastasis by Suppressing the iPLA2/LOX-5/LTB4 Pathway in Hepatocellular Carcinoma Onco Targets Ther, 2020-06-09;13(0):5223-5230. 2020-06-09 [PMID: 32606742] (Human)		Human
L Bertoni, S Jacquet-Gu, T Branly, F Legendre, M Desancé, C Mespoulhes, M Melin, DJ Hartmann, A Schmutz, JM Denoix, P Galéra, M Demoor, F Audigié An experimentally induced osteoarthritis model in horses performed on both metacarpophalangeal and metatarsophalangeal joints: Technical, clinical, imaging, biochemical, macroscopic and microscopic characterization PLoS ONE, 2020-06-25;15(6):e0235251. 2020-06-25 [PMID: 32584901] (Equine)		Equine
Y Wu, Z Wang, Z Lin, X Fu, J Zhan, K Yu Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo Front Pharmacol, 2020-06-03;11(0):682. 2020-06-03 [PMID: 32581777] (Mouse)		Mouse
A Allen, N Vaninov, M Li, S Nguyen, P Igo, AW Tilles, B O'Rourke, BLK Miller, B Parekkadan, RN Barcia Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells Sci Rep, 2020-06-23;10(1):10142. 2020-06-23 [PMID: 32576889] (Human)		Human
XH Xue, JX Xue, W Hu, FL Shi, Y Yang Nomilin targets the Keap1-Nrf2 signalling and ameliorates the development of osteoarthritis J. Cell. Mol. Med., 2020-06-21;0(0):. 2020-06-21 [PMID: 32564468] (Mouse)		Mouse
D Xu, YR Lu, N Kou, MJ Hu, QS Wang, YL Cui Intranasal delivery of icariin via a nanogel-thermoresponsive hydrogel compound system to improve its antidepressant-like activity Int J Pharm, 2020-06-15;586(0):119550. 2020-06-15 [PMID: 32554031] (Rat)		Rat
P Zhu, H Yu, K Zhou, Y Bai, R Qi, S Zhang 3,3'-Diindolylmethane modulates aryl hydrocarbon receptor of esophageal squamous cell carcinoma to reverse epithelial-mesenchymal transition through repressing RhoA/ROCK1-mediated COX2/PGE2 pathway J. Exp. Clin. Cancer Res., 2020-06-16;39(1):113. 2020-06-16 [PMID: 32546278] (Human)		Human
K Lynch, O Treacy, X Chen, N Murphy, P Lohan, MN Islam, E Donohoe, MD Griffin, L Watson, S McLoughlin, G O'Malley, AE Ryan, T Ritter TGF-beta1-Licensed Murine MSCs Show Superior Therapeutic Efficacy in Modulating Corneal Allograft Immune Rejection In�Vivo Mol. Ther., 2020-05-30;0(0):. 2020-05-30 [PMID: 32531237] (Mouse)		Mouse
S Di Blasio, GF van Wigche, A Becker, A van Duffel, M Gorris, K Verrijp, I Stefanini, GJ Bakker, M Bloemendal, A Halilovic, A Vasaturo, G Bakdash, SV Hato, JHW de Wilt, J Schalkwijk, IJM de Vries, JC Textor, EH van den Bo, M Tazzari, CG Figdor The tumour microenvironment shapes dendritic cell plasticity in a human organotypic melanoma culture Nat Commun, 2020-06-02;11(1):2749. 2020-06-02 [PMID: 32488012] (Human)		Human
HJ Lee, JH Ko, HJ Kim, HJ Jeong, JY Oh Mesenchymal stromal cells induce distinct myeloid-derived suppressor cells in inflammation JCI Insight, 2020-06-18;0(0):. 2020-06-18 [PMID: 32453713] (Human)		Human
NF Guo, Z Qiu, XL Chen, X Chen, JB Huang, J Liu Prostaglandin E2 receptor subtypes 1 and 2 play a role in TGF-beta1-induced renal fibrosis by regulating endoplasmic reticulum stress Eur Rev Med Pharmacol Sci, 2020-05-01;24(9):4954-4962. 2020-05-01 [PMID: 32432758] (Mouse)		Mouse
C Behm, A Blufstein, J Gahn, M Nemec, A Moritz, X Rausch-Fan, O Andrukhov Cytokines Differently Define the Immunomodulation of Mesenchymal Stem Cells from the Periodontal Ligament Cells, 2020-05-14;9(5):. 2020-05-14 [PMID: 32423044] (Human)		Human
TM Ha, DC Kim, JH Sohn, JH Yim, H Oh Anti-Inflammatory and Protein Tyrosine Phosphatase 1B Inhibitory Metabolites from the Antarctic Marine-Derived Fungal Strain Penicillium glabrum SF-7123 Mar Drugs, 2020-05-09;18(5):. 2020-05-09 [PMID: 32397523] (Fungus)		Fungus
E Saadi, R Sood, I Dromi, R Srouji, OA Hatoum, S Tal, L Barki-Harr Limited Proteolysis of Cyclooxygenase-2 Enhances Cell Proliferation Int J Mol Sci, 2020-04-30;21(9):. 2020-04-30 [PMID: 32366045] (Human)		Human
F Nishimura, H Mogami, K Moriuchi, Y Chigusa, M Mandai, E Kondoh Mechanisms of thrombin-Induced myometrial contractions: Potential targets of progesterone PLoS ONE, 2020-05-04;15(5):e0231944. 2020-05-04 [PMID: 32365105] (Human)		Human
M Lo Monaco, P Gervois, J Beaumont, P Clegg, A Bronckaers, JM Vandeweerd, I Lambrichts Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis Cells, 2020-04-15;9(4):. 2020-04-15 [PMID: 32326610] (Mouse)		Mouse
CG Kim, DG Lee, J Oh, YH Lee, YJ Lee, PH Song, CH Song, SK Ku Effects of Balneotherapy in Jeju Magma-Seawater on Knee Osteoarthritis Model Sci Rep, 2020-04-20;10(1):6620. 2020-04-20 [PMID: 32313003] (Rat)		Rat
BO Cho, DN Che, JS Kim, JH Kim, JY Shin, HJ Kang, SI Jang In vitro Anti-Inflammatory and Anti-Oxidative Stress Activities of Kushenol C Isolated from the Roots of Sophoraflavescens Molecules, 2020-04-12;25(8):. 2020-04-12 [PMID: 32290603] (Mouse)		Mouse
JA Lopes, VP Rodrigues, MMP Tangerina, LRMD Rocha, CM Nishijima, VVA Nunes, LFR Almeida, W Vilegas, ARSD Santos, M Sannomiya, CA Hiruma-Lim Machaerium hirtum (Vell.) Stellfeld Alleviates Acute Pain and Inflammation: Potential Mechanisms of Action Biomolecules, 2020-04-11;10(4):. 2020-04-11 [PMID: 32290371] (Mouse)		Mouse
HH Park, S Lee, Y Yu, SM Yoo, SY Baek, N Jung, KW Seo, KS Kang TGF-&beta secreted by human umbilical cord blood-derived mesenchymal stem cells ameliorates atopic dermatitis by inhibiting secretion of TNF-&alpha and IgE Stem Cells, 2020-04-14;0(0):. 2020-04-14 [PMID: 32277785] (Human)		Human
L Yang, JY So, N Skrypek, HH Yang, AS Merchant, GW Nelson, WD Chen, H Ishii, JM Chen, G Hu, BR Achyut, EC Yoon, L Han, C Huang, MC Cam, K Zhao, MP Lee Induction of DNMT3B by PGE2 and IL6 at distant metastatic sites promotes epigenetic modification and breast cancer colonization Cancer Res., 2020-04-07;0(0):. 2020-04-07 [PMID: 32265226] (Mouse)		Mouse
T Wongwat, K Srihaphon, C Pitaksuthe, W Boonyo, T Pitaksutee Suppression of inflammatory mediators and matrix metalloproteinase (MMP)-13 by Morus alba stem extract and oxyresveratrol in RAW 264.7?cells and C28/I2 human chondrocytes J Tradit Complement Med, 2019-03-22;10(2):132-140. 2019-03-22 [PMID: 32257876] (Mouse)		Mouse
Y Zhao, J Wang, Z Min, L Peng, S Qi, W Lin I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis Mediators Inflamm., 2020-03-10;2020(0):6947482. 2020-03-10 [PMID: 32256194] (Mouse)		Mouse
KKA Sanjeewa, DP Nagahawatt, HW Yang, JY Oh, TU Jayawarden, YJ Jeon, M De Zoysa, I Whang, B Ryu Octominin Inhibits LPS-Induced Chemokine and Pro-inflammatory Cytokine Secretion from RAW 264.7 Macrophages via Blocking TLRs/NF-kappaB Signal Transduction Biomolecules, 2020-03-27;10(4):. 2020-03-27 [PMID: 32230927] (Mouse)		Mouse
Y Li, L Liu, P Sun, Y Zhang, T Wu, H Sun, KW Cheng, F Chen Fucoxanthinol from the Diatom Nitzschia Laevis Ameliorates Neuroinflammatory Responses in Lipopolysaccharide-Stimulated BV-2 Microglia Mar Drugs, 2020-02-17;18(2):. 2020-02-17 [PMID: 32079242] (Mouse)		Mouse
SA Lee, BR Park, SM Moon, JH Hong, DK Kim, CS Kim Chondroprotective Effect of Cynaroside in IL-1&beta-Induced Primary Rat Chondrocytes and Organ Explants via NF-&kappaB and MAPK Signaling Inhibition Oxid Med Cell Longev, 2020-01-24;2020(0):9358080. 2020-01-24 [PMID: 32047580] (Rat)		Rat
H Liu, X Xiong, W Zhai, T Zhu, X Zhu, Y Zhu, Y Peng, Y Zhang, J Wang, H Chen, Y Chen, A Guo Upregulation of Cytokines and Differentiation of Th17 and Treg by Dendritic Cells: Central Role of Prostaglandin E2 Induced by Mycobacterium bovis Microorganisms, 2020-01-31;8(2):. 2020-01-31 [PMID: 32023904] (Mouse)		Mouse
S Queckbörne, E Syk Lundbe, K Gemzell-Da, LC Davies Endometrial stromal cells exhibit a distinct phenotypic and immunomodulatory profile Stem Cell Res Ther, 2020-01-06;11(1):15. 2020-01-06 [PMID: 31907034] (Human)		Human
EV Sokolova, AO Kravchenko, NV Sergeeva, VN Davydova, LN Bogdanovic, IM Yermak Effect of carrageenans on some lipid metabolism components in vitro Carbohydr Polym, 2019-11-16;230(0):115629. 2019-11-16 [PMID: 31887898] (Human)		Human
P Ma, L Yue, H Yang, Y Fan, J Bai, S Li, J Yuan, Z Zhang, C Yao, M Lin, Q Hou Chondroprotective and anti-inflammatory effects of amurensin H by regulating TLR4/Syk/NF-kappaB signals J. Cell. Mol. Med., 2019-12-25;0(0):. 2019-12-25 [PMID: 31876072] (Rat)		Rat
E Kuca-Warna, U Skalska, I Janicka, U Musia?owic, K Bonek, P G?uszko, P Szcz?sny, M Olesi?ska, E Kontny The Phenotype and Secretory Activity of Adipose-Derived Mesenchymal Stem Cells (ASCs) of Patients with Rheumatic Diseases Cells, 2019-12-17;8(12):. 2019-12-17 [PMID: 31861245] (Human)		Human
S Ni, Z Ling, X Wang, Y Cao, T Wu, R Deng, JL Crane, R Skolasky, S Demehri, G Zhen, A Jain, P Wu, D Pan, B Hu, X Lyu, Y Li, H Chen, H Qi, Y Guan, X Dong, M Wan, X Zou, H Lu, J Hu, X Cao Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice Nat Commun, 2019-12-10;10(1):5643. 2019-12-10 [PMID: 31822662] (Mouse)		Mouse
SY Kim, SH Oh, JH Lee, MW Suh, MK Park Effects of Placenta-Derived Mesenchymal Stem Cells on the Particulate Matter-Induced Damages in Human Middle Ear Epithelial Cells Stem Cells Int, 2019-11-14;2019(0):4357684. 2019-11-14 [PMID: 31814835] (Human)		Human
H Cho, FU Bhatti, KA Hasty, AK Yi Nanosome-Mediated Delivery Of Protein Kinase D Inhibitor Protects Chondrocytes From Interleukin-1beta-Induced Stress And Apoptotic Death Int J Nanomedicine, 2019-11-11;14(0):8835-8846. 2019-11-11 [PMID: 31806974] (Porcine)		Porcine
B Sun, Y Ma, F Wang, L Hu, Y Sun miR-644-5p carried by bone mesenchymal stem cell-derived exosomes targets regulation of p53 to inhibit ovarian granulosa cell apoptosis Stem Cell Res Ther, 2019-11-29;10(1):360. 2019-11-29 [PMID: 31783913] (Mouse)		Mouse
D Chen, D Lu, H Liu, E Xue, Y Zhang, P Shang, X Pan Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-alpha-driven inflammation and ER stress EBioMedicine, 2019-11-14;0(0):. 2019-11-14 [PMID: 31735552] (Human)		Human
JMO Freire, HV Chaves, AH Teixeira, LHT de Sousa, IR Pinto, JJDN Costa, NA de Sousa, KMA Pereira, VCC Girão, VCS Ferreira, JEÁ Dos Santos, MAS Lima, ATA Pimenta, RC Montenegro, MEA de Moraes, VPT Pinto, GC Filho, MM Bezerra Protective effect of Platymiscium floribundum Vog. in tree extract on periodontitis inflammation in rats PLoS ONE, 2019-11-04;14(11):e0223800. 2019-11-04 [PMID: 31682614] (Rat)		Rat
? Uram, M Misiorek, M Pichla, A Filipowicz, J Markowicz, S Wo?owiec, E Wa?ajtys-R The Effect of Biotinylated PAMAM G3 Dendrimers Conjugated with COX-2 Inhibitor (celecoxib) and PPARgammaAgonist (Fmoc-L-Leucine) on Human Normal Fibroblasts, Immortalized Keratinocytes and Glioma Cells in Vitro Molecules, 2019-10-22;24(20):. 2019-10-22 [PMID: 31652556] (Human)		Human
M Vijarnsorn, I Kwananocha, N Kashemsant, T Jarudecha, C Lekcharoen, B Beale, B Peirone, BDX Lascelles The effectiveness of marine based fatty acid compound (PCSO-524) and firocoxib in the treatment of canine osteoarthritis BMC Vet. Res., 2019-10-17;15(1):349. 2019-10-17 [PMID: 31623621] (Human)		Human
S Regmi, S Pathak, TP Thanh, TT Nguyen, JH Sung, S Yook, JO Kim, CS Yong, I Choi, KO Doh, PH Park, JB Park, Y Seo, BK Kim, DM Lee, IJ Moon, HS Kim, JH Jeong Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity Stem Cell Res Ther, 2019-10-16;10(1):230. 2019-10-16 [PMID: 31615539] (Human)		Human
SM Lee, NH Kim, S Lee, YN Kim, JD Heo, JR Rho, EJ Jeong (10Z)-Debromohymenialdisine from Marine Sponge Stylissa sp. Regulates Intestinal Inflammatory Responses in Co-Culture Model of Epithelial Caco-2 Cells and THP-1 Macrophage Cells Molecules, 2019-09-18;24(18):. 2019-09-18 [PMID: 31540496] (Human)		Human
W Pearson, LS Kott A biological extract of turmeric (Curcuma longa) modulates response of cartilage explants to lipopolysaccharide BMC Complement Altern Med, 2019-09-11;19(1):252. 2019-09-11 [PMID: 31506082] (Porcine)		Porcine
TJ Bartosh, JH Ylostalo Efficacy of 3D Culture Priming is Maintained in Human Mesenchymal Stem Cells after Extensive Expansion of the Cells Cells, 2019-09-05;8(9):. 2019-09-05 [PMID: 31491901] (Human)		Human
Y Shibaike, M Gotoh, C Ogawa, S Nakajima, K Yoshikawa, T Kobayashi, K Murakami-M 2-Carba cyclic phosphatidic acid inhibits lipopolysaccharide-induced prostaglandin E2 production in a human macrophage cell line Biochem Biophys Rep, 2019-07-19;19(0):100668. 2019-07-19 [PMID: 31367683] (Human)		Human
YM Woo, OJ Kim, ES Jo, SJ Kim, YH Lee, MY Ahn, SH Lee, JM Ha, A Kim Anti-inflammatory effects of the combined extracts of Achyranthes japonica nakai and Aralia continentalis kitagawa in�vitro and in�vivo Data Brief, 2019-06-03;25(0):104088. 2019-06-03 [PMID: 31294054] (Rat)		Rat
L Bertoni, T Branly, S Jacquet, M Desancé, L Desquilbet, P Rivory, DJ Hartmann, JM Denoix, F Audigié, P Galéra, M Demoor Intra-Articular Injection of 2 Different Dosages of Autologous and Allogeneic Bone Marrow- and Umbilical Cord-Derived Mesenchymal Stem Cells Triggers a Variable Inflammatory Response of the Fetlock Joint on 12 Sound Experimental Horses Stem Cells Int, 2019-05-02;2019(0):9431894. 2019-05-02 [PMID: 31191689] (Equine)		Equine
Y Liu, H Ren, Y Zhou, L Shang, Y Zhang, F Yang, X Shi The hypoxia conditioned mesenchymal stem cells promote hepatocellular carcinoma progression through YAP mediated lipogenesis reprogramming J. Exp. Clin. Cancer Res., 2019-05-29;38(1):228. 2019-05-29 [PMID: 31142342] (Human)		Human
CH Yu, B Suh, I Shin, EH Kim, D Kim, YJ Shin, SY Chang, SH Baek, H Kim, ON Bae Inhibitory Effects of a Novel Chrysin-Derivative, CPD 6, on Acute and Chronic Skin Inflammation Int J Mol Sci, 2019-05-28;20(11):. 2019-05-28 [PMID: 31141897] (Human, Mouse)		Human, Mouse
DW Barrett, RK John, C Thrasivoul, A Mata, JA Deprest, DL Becker, AL David, TT Chowdhury Targeting mechanotransduction mechanisms and tissue weakening signals in the human amniotic membrane Sci Rep, 2019-04-30;9(1):6718. 2019-04-30 [PMID: 31040291] (Bioassay, Human)	Bioassay	Human
YG Lee, H Lee, JA Ryuk, JT Hwang, HG Kim, DS Lee, YJ Kim, DC Yang, BS Ko, NI Baek 6-Methoxyflavonols from the aerial parts of Tetragonia tetragonoides (Pall.) Kuntze and their anti-inflammatory activity Bioorg. Chem., 2019-04-11;88(0):102922. 2019-04-11 [PMID: 31003077] (Mouse)		Mouse
N Van Thanh, HJ Jang, LB Vinh, KTP Linh, PTT Huong, NX Cuong, NH Nam, C Van Minh, YH Kim, SY Yang Chemical constituents from Vietnamese mangrove Calophyllum inophyllum and their anti-inflammatory effects Bioorg. Chem., 2019-04-11;88(0):102921. 2019-04-11 [PMID: 30991191] (Mouse)		Mouse
L Song, X Yuan, Z Jones, K Griffin, Y Zhou, T Ma, Y Li Assembly of Human Stem Cell-Derived Cortical Spheroids and Vascular Spheroids to Model 3-D Brain-like Tissues Sci Rep, 2019-04-12;9(1):5977. 2019-04-12 [PMID: 30979929] (Human)		Human
N Kangwan, K Pintha, S Lekawanvij, M Suttajit Rosmarinic Acid Enriched Fraction from Perilla frutescens Leaves Strongly Protects Indomethacin-Induced Gastric Ulcer in Rats Biomed Res Int, 2019-03-04;2019(0):9514703. 2019-03-04 [PMID: 30949513] (Rat)		Rat
XJ Li, KW Kim, H Oh, XQ Liu, YC Kim Chemical Constituents and an Antineuroinflammatory Lignan, Savinin from the Roots of Acanthopanax henryi Evid Based Complement Alternat Med, 2019-02-21;2019(0):1856294. 2019-02-21 [PMID: 30915141] (Mouse)		Mouse
V Miceli, M Pampalone, S Vella, AP Carreca, G Amico, PG Conaldi Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems Stem Cells Int, 2019-02-18;2019(0):7486279. 2019-02-18 [PMID: 30911299] (Human)		Human
A Islam, I Urbarova, JA Bruun, I Martinez-Z Large-scale secretome analyses unveil the superior immunosuppressive phenotype of umbilical cord stromal cells as compared to other adult mesenchymal stromal cells Eur Cell Mater, 2019-02-20;37(0):153-174. 2019-02-20 [PMID: 30785213] (Human)		Human
D Zhu, C Chen, L Bai, L Kong, J Luo Downregulation of Aquaporin 3 Mediated the Laxative Effect in the Rat Colon by a Purified Resin Glycoside Fraction from Pharbitis Semen Evid Based Complement Alternat Med, 2019-01-13;2019(0):9406342. 2019-01-13 [PMID: 30733814] (Human, Rat)		Human, Rat
X Zhao, J Li, Y Meng, M Cao, J Wang Treatment Effects of Jinlingzi Powder and Its Extractive Components on Gastric Ulcer Induced by Acetic Acid in Rats Evid Based Complement Alternat Med, 2019-01-03;2019(0):7365841. 2019-01-03 [PMID: 30719066] (Rat)		Rat
YY Dai, SY Ni, K Ma, YS Ma, ZS Wang, XL Zhao Stem cells from human exfoliated deciduous teeth correct the immune imbalance of allergic rhinitis via Treg cells in vivo and in vitro Stem Cell Res Ther, 2019-01-22;10(1):39. 2019-01-22 [PMID: 30670101] (Human)		Human
XY Jia, Y Chang, F Wei, X Dai, YJ Wu, XJ Sun, S Xu, HX Wu, C Wang, XZ Yang, W Wei CP-25 reverses prostaglandin E4 receptor desensitization-induced fibroblast-like synoviocyte dysfunction via the G protein-coupled receptor kinase 2 in autoimmune arthritis Acta Pharmacol. Sin., 2019-01-14;0(0):. 2019-01-14 [PMID: 30643209] (Rat)		Rat
H Jeon, WJ Yoon, YM Ham, SA Yoon, SC Kang Anti-Arthritis Effect through the Anti-Inflammatory Effect of Sargassum muticum Extract in Collagen-Induced Arthritic (CIA) Mice Molecules, 2019-01-13;24(2):. 2019-01-13 [PMID: 30642121] (Mouse)		Mouse
L Jiang, Q Jiang, S Yang, S Huang, X Han, J Duan, S Pan, M Zhao, S Guo GYY4137 attenuates LPS-induced acute lung injury via heme oxygenase-1 modulation Pulm Pharmacol Ther, 2018-12-31;0(0):. 2018-12-31 [PMID: 30605726] (Mouse)		Mouse
X Li, J Lin, X Ding, J Xuan, Z Hu, D Wu, X Zhu, Z Feng, W Ni, A Wu The protective effect of sinapic acid in osteoarthritis: In vitro and in vivo studies J. Cell. Mol. Med., 2019-01-03;0(0):. 2019-01-03 [PMID: 30604480] (Human)		Human
AN Won, SA Kim, JY Ahn, JH Han, CH Kim, JH Lee, DI Kim HO-1 Induction by Selaginella tamariscina Extract Inhibits Inflammatory Response in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages Evid Based Complement Alternat Med, 2018-11-18;2018(0):7816923. 2018-11-18 [PMID: 30581485] (Mouse)		Mouse
YS Lee, CH Lee, JT Bae, KT Nam, DB Moon, OK Hwang, JS Choi, TH Kim, HO Jun, YS Jung, DY Hwang, SB Han, DY Yoon, JT Hong Inhibition of skin carcinogenesis by suppression of NF-?B dependent ITGAV and TIMP-1 expression in IL-32? overexpressed condition J. Exp. Clin. Cancer Res., 2018-11-28;37(1):293. 2018-11-28 [PMID: 30486830] (Mouse)		Mouse
J Hou, Y Gu, S Zhao, M Huo, S Wang, Y Zhang, Y Qiao, X Li Anti-Inflammatory Effects of Aurantio-Obtusin from Seed of Cassia obtusifolia L. through Modulation of the NF-?B Pathway Molecules, 2018-11-27;23(12):. 2018-11-27 [PMID: 30486383] (Mouse)		Mouse
TH Tseng, WL Lin, CK Chang, KC Lee, SY Tung, HC Kuo Protective Effects of Morus Root Extract (MRE) Against Lipopolysaccharide-Activated RAW264.7 Cells and CCl4-Induced Mouse Hepatic Damage Cell. Physiol. Biochem., 2018-11-27;51(3):1376-1388. 2018-11-27 [PMID: 30481781] (Mouse)		Mouse
WY Chen, CY Chang, JR Li, JD Wang, CC Wu, YH Kuan, SL Liao, WY Wang, CJ Chen Anti-inflammatory and Neuroprotective Effects of Fungal Immunomodulatory Protein Involving Microglial Inhibition Int J Mol Sci, 2018-11-21;19(11):. 2018-11-21 [PMID: 30469316] (Rat)		Rat
M Longo, V Gouveia Ga, E Ervolino, ML Ferro Alve, C Duque, M Wainwright, LH Theodoro Multiple aPDT sessions on periodontitis in rats treated with chemotherapy: Histomorphometrical, Immunohistochemical, Imunological and Microbiological Analyses Photodiagnosis Photodyn Ther, 2018-11-20;0(0):. 2018-11-20 [PMID: 30468900] (Rat)		Rat
S Rutting, M Papanicola, D Xenaki, LG Wood, AM Mullin, PM Hansbro, BG Oliver Dietary ?-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD Respir. Res., 2018-11-03;19(1):211. 2018-11-03 [PMID: 30390648] (Human)		Human
JE Millán-Riv, FM Nadal-Nico, D García-Ber, P Sobrado-Ca, M Blanquer, JM Moraleda, M Vidal-Sanz, M Agudo-Barr Human Wharton's jelly mesenchymal stem cells protect axotomized rat retinal ganglion cells via secretion of anti-inflammatory and neurotrophic factors Sci Rep, 2018-11-02;8(1):16299. 2018-11-02 [PMID: 30389962] (Human)		Human
CT Hsieh, YJ Lee, X Dai, NB Ojeda, HJ Lee, LT Tien, LW Fan Systemic Lipopolysaccharide-Induced Pain Sensitivity and Spinal Inflammation Were Reduced by Minocycline in Neonatal Rats Int J Mol Sci, 2018-09-27;19(10):. 2018-09-27 [PMID: 30262747] (Rat)		Rat
M Li, M Zeng, ZG Zhang, B Zhang, J Zhang, X Zheng, W Feng Lepidiumuridine A: A New Natural Uridine Derivative as a Phytoestrogen Isolated from the Seeds of Lepidium apetalum Willd Evid Based Complement Alternat Med, 2018-09-04;2018(0):2813465. 2018-09-04 [PMID: 30254685] (Mouse)		Mouse
W Dankers, C González-L, N Davelaar, PS Asmawidjaj, AMC Mus, JMW Hazes, EM Colin, E Lubberts 1,25(OH)2D3 and dexamethasone additively suppress synovial fibroblast activation by CCR6+ T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade Arthritis Res. Ther., 2018-09-20;20(1):212. 2018-09-20 [PMID: 30236152] (Human)		Human
CS Yoon, DC Kim, JS Park, KW Kim, YC Kim, H Oh Isolation of Novel Sesquiterpeniods and Anti-neuroinflammatory Metabolites from Nardostachys jatamansi Molecules, 2018-09-17;23(9):. 2018-09-17 [PMID: 30227591] (Mouse)		Mouse
LC Dutton, J Dudhia, B Catchpole, H Hodgkiss-G, D Werling, DJ Connolly Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor Sci Rep, 2018-09-06;8(1):13351. 2018-09-06 [PMID: 30190508] (Canine)		Canine
J Zhou, L Chen, Z Liu, L Sang, Y Li, D Yuan Changes in erythrocyte polyunsaturated fatty acids and plasma eicosanoids level in patients with asthma Lipids Health Dis, 2018-09-01;17(1):206. 2018-09-01 [PMID: 30172255] (Human)		Human
H Wu, H Pang, Y Chen, L Huang, H Liu, Y Zheng, C Sun, G Zhang, G Wang Anti-Inflammatory Effect of a Polyphenol-Enriched Fraction from Acalypha wilkesiana on Lipopolysaccharide-Stimulated RAW 264.7 Macrophages and Acetaminophen-Induced Liver Injury in Mice Oxid Med Cell Longev, 2018-08-07;2018(0):7858094. 2018-08-07 [PMID: 30159118] (Mouse)		Mouse
X Li, D Wu, Z Hu, J Xuan, X Ding, G Zheng, Z Feng, W Ni, A Wu The Protective Effect of Ligustilide in Osteoarthritis: An in Vitro and in Vivo Study Cell. Physiol. Biochem., 2018-08-17;48(6):2583-2595. 2018-08-17 [PMID: 30121673] (Human)		Human
Y Li, J Shi, S Qi, J Zhang, D Peng, Z Chen, G Wang, Z Wang, L Wang IL-33 facilitates proliferation of colorectal cancer dependent on�COX2/PGE2 J. Exp. Clin. Cancer Res., 2018-08-17;37(1):196. 2018-08-17 [PMID: 30119635] (Human)		Human
JW Park, SH Han, T Hanawa Effects of Surface Nanotopography and Calcium Chemistry of Titanium Bone Implants on Early Blood Platelet and Macrophage Cell Function Biomed Res Int, 2018-07-04;2018(0):1362958. 2018-07-04 [PMID: 30069461] (Human)		Human
HK Lee, KH Kim, HS Kim, JS Kim, JH Lee, A Ji, KS Kim, TY Lee, IY Chang, SC Bae, JT Hong, Y Kim, SB Han Effect of a Combination of Prednisone or Mycophenolate Mofetil and Mesenchymal Stem Cells on Lupus Symptoms in MRL.Faslpr Mice Stem Cells Int, 2018-07-03;2018(0):4273107. 2018-07-03 [PMID: 30057623] (Human)		Human
P Silwal, K Lim, JY Heo, JI Park, U Namgung, SK Park Adenine attenuates lipopolysaccharide-induced inflammatory reactions Korean J. Physiol. Pharmacol., 2018-06-25;22(4):379-389. 2018-06-25 [PMID: 29962852] (Mouse)		Mouse
MH Lee, AR Han, M Jang, HK Choi, SY Lee, KT Kim, TG Lim Antiskin Inflammatory Activity of Black Ginger (Kaempferia parviflora) through Antioxidative Activity Oxid Med Cell Longev, 2018-04-03;2018(0):5967150. 2018-04-03 [PMID: 29849904] (Mouse)		Mouse
Y Zhou, G Wang, D Li, Y Wang, Q Wu, J Shi, F Zhang Dual modulation on glial cells by tetrahydroxystilbene glucoside protects against dopamine neuronal loss J Neuroinflammation, 2018-05-25;15(1):161. 2018-05-25 [PMID: 29801454] (Rat)		Rat
R Kalra, E Bhagyaraj, D Tiwari, R Nanduri, AP Chacko, M Jain, S Mahajan, N Khatri, P Gupta AIRE promotes androgen-independent prostate cancer by directly regulating IL-6 and modulating tumor microenvironment Oncogenesis, 2018-05-25;7(5):43. 2018-05-25 [PMID: 29795364] (Human)		Human
M Li, D Khong, LY Chin, A Singleton, B Parekkadan Therapeutic Delivery Specifications Identified Through Compartmental Analysis of a Mesenchymal Stromal Cell-Immune Reaction Sci Rep, 2018-05-01;8(1):6816. 2018-05-01 [PMID: 29717209] (Human)		Human
JA Ocana, E Romer, R Sahu, SC Pawelzik, GA FitzGerald, MH Kaplan, JB Travers Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms J. Immunol., 2018-04-25;0(0):. 2018-04-25 [PMID: 29695417] (Mouse)		Mouse
I Kang, BC Lee, SW Choi, JY Lee, JJ Kim, BE Kim, DH Kim, SE Lee, N Shin, Y Seo, HS Kim, DI Kim, KS Kang Donor-dependent variation of human umbilical cord blood mesenchymal stem cells in response to hypoxic preconditioning and amelioration of limb ischemia Exp. Mol. Med., 2018-04-20;50(4):35. 2018-04-20 [PMID: 29674661] (Human)		Human
X Jiang, MR Du, M Li, H Wang Three macrophage subsets are identified in the uterus during early human pregnancy Cell. Mol. Immunol., 2018-04-04;0(0):. 2018-04-04 [PMID: 29618777] (Human)		Human
HJ Park, J Kim, FT Saima, KJ Rhee, S Hwang, MY Kim, SK Baik, YW Eom, HS Kim Adipose-derived stem cells ameliorate colitis by suppression of inflammasome formation and regulation of M1-macrophage population through prostaglandin E2 Biochem. Biophys. Res. Commun., 2018-03-16;0(0):. 2018-03-16 [PMID: 29550474] (Human)		Human
MM Rahman, HK Kim, SE Kim, MJ Kim, DH Kim, HS Lee Chondroprotective Effects of a Standardized Extract (KBH-JP-040) from Kalopanax pictus, Hericium erinaceus, and Astragalus membranaceus in Experimentally Induced In Vitro and In Vivo Osteoarthritis Models Nutrients, 2018-03-15;10(3):. 2018-03-15 [PMID: 29543781] (Rat)		Rat
KW Kim, TH Quang, W Ko, DC Kim, CS Yoon, H Oh, YC Kim Anti-neuroinflammatory effects of cudraflavanone A isolated from the chloroform fraction of Cudrania tricuspidata root bark Pharm Biol, 2018-12-01;56(1):192-200. 2018-12-01 [PMID: 29521141] (Mouse)		Mouse
JY Xiao, BR Xiong, W Zhang, WC Zhou, H Yang, F Gao, HB Xiang, A Manyande, XB Tian, YK Tian PGE2-EP3 signaling exacerbates hippocampus-dependent cognitive impairment after laparotomy by reducing expression levels of hippocampal synaptic plasticity-related proteins in aged mice CNS Neurosci Ther, 2018-02-27;0(0):. 2018-02-27 [PMID: 29488342] (Mouse)		Mouse
SJ Kim, WK Ko, MJ Jo, Y Arai, H Choi, H Kumar, IB Han, S Sohn Anti-inflammatory effect of Tauroursodeoxycholic acid in RAW 264.7 macrophages, Bone marrow-derived macrophages, BV2 microglial cells, and spinal cord injury Sci Rep, 2018-02-16;8(1):3176. 2018-02-16 [PMID: 29453346] (Mouse)		Mouse
ME McCarthy, CS Buhimschi, JT Hardy, AT Dulay, CA Laky, MO Bahtyiar, R Papanna, G Zhao, IA Buhimschi Identification of haptoglobin switch-on status in archived placental specimens indicates antenatal exposure to inflammation and potential participation of the fetus in triggering preterm birth Placenta, 2017-12-24;62(0):50-57. 2017-12-24 [PMID: 29405967] (Human)		Human
A Ooki, A Begum, L Marchionni, CJ VandenBuss, S Mao, K Max, MO Hoque Arsenic Promotes the COX2/PGE2-SOX2 Axis to Increase the Malignant Stemness Properties of Urothelial Cells Int. J. Cancer, 2018-02-14;0(0):. 2018-02-14 [PMID: 29396848] (Human)		Human
AN Bradbery, JA Coverdale, KL Vernon, JL Leatherwoo, CE Arnold, RA Dabareiner, MK Kahn, AA Millican, TH Welsh Evaluation of conjugated linoleic acid (CLA) supplementation on markers of joint inflammation and cartilage metabolism in young horses challenged with lipopolysaccharide J. Anim. Sci., 2018-03-06;0(0):. 2018-03-06 [PMID: 29385470] (Equine)		Equine
SG Cao, H Wang, LM Lin, XP Xia, H Wu Cryptotanshinone inhibits prostaglandin E2 production and COX-2 expression via suppression of TLR4/NF-?B signaling pathway in LPS-stimulated Caco-2 cells Microb. Pathog., 2018-01-17;0(0):. 2018-01-17 [PMID: 29353005] (Human)		Human
DJ Allison, DA Gabriel, P Klentrou, AR Josse, DS Ditor The Influence of Chronic Inflammation on Peripheral Motor Nerve Conduction Following Spinal Cord Injury: A Randomized Clinical Trial Top Spinal Cord Inj Rehabil, 2017-01-01;23(4):377-385. 2017-01-01 [PMID: 29339913] (Human)		Human
L Subedi, OW Kwon, C Pak, G Lee, K Lee, H Kim, SY Kim N,N-disubstituted azines attenuate LPS-mediated neuroinflammation in microglia and neuronal apoptosis via inhibiting MAPK signaling pathways BMC Neurosci, 2017-12-28;18(1):82. 2017-12-28 [PMID: 29281977] (Human)		Human
L Cui, Y Zhao, Y Pan, X Zheng, D Shao, Y Jia, K He, K Li, L Chen Chemotherapy induces ovarian cancer cell repopulation through the caspase 3-mediated arachidonic acid metabolic pathway Onco Targets Ther, 2017-12-08;10(0):5817-5826. 2017-12-08 [PMID: 29263678] (Human)		Human
YK Kim, MG Yeo, BK Oh, HY Kim, HJ Yang, SS Cho, M Gil, KJ Lee Tussilagone Inhibits the Inflammatory Response and Improves Survival in CLP-Induced Septic Mice Int J Mol Sci, 2017-12-18;18(12):. 2017-12-18 [PMID: 29258263] (Mouse)		Mouse
W Zheng, Z Feng, Y Lou, C Chen, C Zhang, Z Tao, H Li, L Cheng, X Ying Silibinin protects against osteoarthritis through inhibiting the inflammatory response and cartilage matrix degradation in vitro and in vivo Oncotarget, 2017-08-24;8(59):99649-99665. 2017-08-24 [PMID: 29245931] (Human)		Human
T Lin, J Pajarinen, A Nabeshima, L Lu, K Nathan, E Jämsen, Z Yao, SB Goodman Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis Stem Cell Res Ther, 2017-12-06;8(1):277. 2017-12-06 [PMID: 29212557] (Mouse)		Mouse
A Ooki, M Del Carmen, L Marchionni, W Dinalankar, A Begum, NM Hahn, CJ VandenBuss, ZA Rasheed, S Mao, GJ Netto, D Sidransky, MO Hoque YAP1 and COX2 coordinately regulate urothelial cancer stem-like cells Cancer Res., 2017-11-27;0(0):. 2017-11-27 [PMID: 29180467] (Human)		Human
H Gao, Y Song, D Li, W Feng, J Liu Saikosaponin A inhibits IL-1?-induced inflammatory mediators in human osteoarthritis chondrocytes by activating LXR? Oncotarget, 2017-09-30;8(51):88941-88950. 2017-09-30 [PMID: 29179489] (Human)		Human
X Yang, MC Kang, Y Li, EA Kim, SM Kang, YJ Jeon Asperflavin, an Anti-Inflammatory Compound Produced by a Marine-Derived Fungus, Eurotium amstelodami Molecules, 2017-10-29;22(11):. 2017-10-29 [PMID: 29109367] (Mouse)		Mouse
SR Oh, S Ok, TS Jung, SO Jeon, JM Park, JW Jung, DS Ryu Protective effect of decursin and decursinol angelate-rich Angelica gigas Nakai extract on dextran sulfate sodium-induced murine ulcerative colitis Asian Pac J Trop Med, 2017-09-13;10(9):864-870. 2017-09-13 [PMID: 29080614] (Mouse)		Mouse
JW Jeong, HH Lee, J Kim, EO Choi, H Hwang-Bo, HJ Kim, MY Kim, KI Ahn, GY Kim, KW Lee, KY Kim, SG Kim, SH Hong, C Park, HJ Cha, YH Choi Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate?induced osteoarthritis rats Mol Med Rep, 2017-07-21;0(0):. 2017-07-21 [PMID: 29067461] (Rat)		Rat
HS Helmy, AE El-Sahar, RH Sayed, RN Shamma, AH Salama, EM Elbaz Therapeutic effects of lornoxicam-loaded nanomicellar formula in experimental models of rheumatoid arthritis Int J Nanomedicine, 2017-09-22;12(0):7015-7023. 2017-09-22 [PMID: 29026298] (Rat)		Rat
JN Kim, SN Han, TJ Ha, HK Kim Black soybean anthocyanins attenuate inflammatory responses by suppressing reactive oxygen species production and mitogen activated protein kinases signaling in lipopolysaccharide-stimulated macrophages Nutr Res Pract, 2017-09-18;11(5):357-364. 2017-09-18 [PMID: 28989571] (Mouse)		Mouse
L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis Autophagy, 2017-01-01;0(0):0. 2017-01-01 [PMID: 28933598] (Mouse)		Mouse
S Galland, J Vuille, P Martin, I Letovanec, A Caignard, G Fregni, I Stamenkovi Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets Cell Rep, 2017-09-19;20(12):2891-2905. 2017-09-19 [PMID: 28930684] (Human)		Human
SH Kim, HJ Choi, WK Yang, JE Lee, JH Cho, IJ Park, S Park, BK Park, M Jin Suppressive Effect of the n-Hexane Extract of Litsea japonica Fruit Flesh on Monosodium-Iodoacetate-Induced Osteoarthritis in Rats Evid Based Complement Alternat Med, 2017-08-22;2017(0):1791403. 2017-08-22 [PMID: 28904551] (Mouse)		Mouse
Z Zhuang, G Ye, B Huang Kaempferol Alleviates the Interleukin-1?-Induced Inflammation in Rat Osteoarthritis Chondrocytes via Suppression of NF-?B Med. Sci. Monit., 2017-08-14;23(0):3925-3931. 2017-08-14 [PMID: 28806392] (Rat)		Rat
Y Gao, H Zhang, L Luo, J Lin, D Li, S Zheng, H Huang, S Yan, J Yang, Y Hao, H Li, F Gao Smith, S Jin Resolvin D1 Improves the Resolution of Inflammation via Activating NF-?B p50/p50-Mediated Cyclooxygenase-2 Expression in Acute Respiratory Distress Syndrome J. Immunol., 2017-08-09;0(0):. 2017-08-09 [PMID: 28794232] (Rat)		Rat
JM Garth, KM Reeder, MS Godwin, JJ Mackel, CW Dunaway, JP Blackburn, C Steele IL-33 Signaling Regulates Innate IL-17A and IL-22 Production via Suppression of Prostaglandin E2 during Lung Fungal Infection J. Immunol., 2017-08-07;199(6):2140-2148. 2017-08-07 [PMID: 28784844] (Mouse)		Mouse
J Jeon, LJ Kang, KM Lee, C Cho, EK Song, W Kim, TJ Park, S Yang 3'-Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis J. Cell. Mol. Med., 2017-08-07;0(0):. 2017-08-07 [PMID: 28782172] (Mouse)		Mouse
CW Cho, S Ahn, TG Lim, HD Hong, YK Rhee, DC Yang, M Jang Cynanchum wilfordii Polysaccharides Suppress Dextran Sulfate Sodium-Induced Acute Colitis in Mice and the Production of Inflammatory Mediators from Macrophages Mediators Inflamm., 2017-06-20;2017(0):3859856. 2017-06-20 [PMID: 28751820] (Mouse)		Mouse
SA Engen, GH Rørvik, O Schreurs, IJ Blix, K Schenck The oral commensal Streptococcus mitis activates the aryl hydrocarbon receptor in human oral epithelial cells Int J Oral Sci, 2017-06-16;0(0):. 2017-06-16 [PMID: 28621325] (Human)		Human
S Kispert, T Schwartz, J McHowat Cigarette Smoke Regulates Calcium-Independent Phospholipase A2 Metabolic Pathways in Breast Cancer Am. J. Pathol., 2017-06-12;0(0):. 2017-06-12 [PMID: 28618256] (Human)		Human
Y Xiao, H Yan, H Diao, B Yu, J He, J Yu, P Zheng, X Mao, Y Luo, D Chen Early Gut Microbiota Intervention Suppresses DSS-Induced Inflammatory Responses by Deactivating TLR/NLR Signalling in Pigs Sci Rep, 2017-06-12;7(1):3224. 2017-06-12 [PMID: 28607413] (Porcine)		Porcine
ATV Ho, AR Palla, MR Blake, ND Yucel, YX Wang, KEG Magnusson, CA Holbrook, PE Kraft, SL Delp, HM Blau Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength Proc. Natl. Acad. Sci. U.S.A., 2017-06-12;0(0):. 2017-06-12 [PMID: 28607093] (Mouse)		Mouse
AK Talukder, MS Yousef, MB Rashid, K Awai, TJ Acosta, T Shimizu, K Okuda, M Shimada, K Imakawa, A Miyamoto Bovine embryo induces an anti-inflammatory response in uterine epithelial cells and immune cells in vitro: possible involvement of interferon tau as an intermediator J. Reprod. Dev., 2017-06-10;0(0):. 2017-06-10 [PMID: 28603222] (Bovine)		Bovine
N Yao, N Chen, X Xu, D Sun, W Liu, G Li, X Bi, S Li, Z Chen, G Chen, H Gan Protective effect of Shenmai injection on knee articular cartilage of osteoarthritic rabbits and IL-1?-stimulated human chondrocytes Exp Ther Med, 2017-04-18;13(6):3013-3020. 2017-04-18 [PMID: 28587374] (Human)		Human
A Paulrayer, A Adithan, JH Lee, KH Moon, DG Kim, SY Im, CW Kang, NS Kim, JH Kim Aronia melanocarpa (Black Chokeberry) Reduces Ethanol-Induced Gastric Damage via Regulation of HSP-70, NF-?B, and MCP-1 Signaling Int J Mol Sci, 2017-06-05;18(6):. 2017-06-05 [PMID: 28587230] (Rat)		Rat
DH Kwon, JW Jeong, EO Choi, HW Lee, KW Lee, KY Kim, SG Kim, SH Hong, GY Kim, C Park, HJ Hwang, CG Son, YH Choi Inhibitory effects on the production of inflammatory mediators and reactive oxygen species by Mori folium in lipopolysaccharide-stimulated macrophages and zebrafish An. Acad. Bras. Cienc., 2017-05-01;89(1):661-674. 2017-05-01 [PMID: 28562828] (Mouse)		Mouse
Y Lu, J Lou, X Liu, S Wang Oxysophocarpine reduces oxygen-glucose deprivation-induced microglial activation and injury Am J Transl Res, 2017-05-15;9(5):2266-2275. 2017-05-15 [PMID: 28559977] (Mouse)		Mouse
XR Wang, HG Hao, L Chu Glycyrrhizin inhibits LPS-induced inflammatory mediator production in endometrial epithelial cells Microb. Pathog., 2017-05-25;0(0):. 2017-05-25 [PMID: 28552807] (Mouse)		Mouse
LC Kinkead, DC Fayram, LH Allen Francisella novicida inhibits spontaneous apoptosis and extends human neutrophil lifespan J. Leukoc. Biol., 2017-05-26;0(0):. 2017-05-26 [PMID: 28550119] (Human)		Human
K Torii, N Maeshige, M Aoyama-Ish, M Miyoshi, H Terashi, M Usami Combination therapy with butyrate and docosahexaenoic acid for keloid fibrogenesis: an in vitro study An Bras Dermatol, 2017-03-01;92(2):184-190. 2017-03-01 [PMID: 28538876] (Human)		Human
SY Park, ML Jin, NJ Kang, G Park, YW Choi Anti-inflammatory effects of novel polygonum multiflorum compound via inhibiting NF-?B/MAPK and upregulating the Nrf2 pathways in LPS-stimulated microglia Neurosci. Lett., 2017-04-27;0(0):. 2017-04-27 [PMID: 28458018] (Mouse)		Mouse
XJ Jia, X Li, F Wang, HQ Liu, DJ Zhang, Y Chen Berbamine Exerts Anti-Inflammatory Effects via Inhibition of NF-?B and MAPK Signaling Pathways Cell. Physiol. Biochem., 2017-04-26;41(6):2307-2318. 2017-04-26 [PMID: 28456802] (Mouse)		Mouse
G Qiu, G Zheng, M Ge, L Huang, H Tong, P Chen, D Lai, Y Hu, B Cheng, Q Shu, J Xu Adipose-derived mesenchymal stem cells modulate CD14(++)CD16(+) expression on monocytes from sepsis patients in vitro via prostaglandin E2 Stem Cell Res Ther, 2017-04-26;8(1):97. 2017-04-26 [PMID: 28446249] (Human)		Human
HJ Park, M Song Leaves of Raphanus sativus L. Shows Anti-Inflammatory Activity in LPS-Stimulated Macrophages via Suppression of COX-2 and iNOS Expression Prev Nutr Food Sci, 2017-03-31;22(1):50-55. 2017-03-31 [PMID: 28401088] (Mouse)		Mouse
AM Silverstei, RM Stefani, E Sobczak, EL Tong, MG Attur, RP Shah, JC Bulinski, GA Ateshian, CT Hung Toward understanding the role of cartilage particulates in synovial inflammation Osteoarthr. Cartil., 2017-03-30;0(0):. 2017-03-30 [PMID: 28365462] (Human)		Human
I Rudnik-Jan, S Colen, J Berard, S Plomp, I Que, M van Rijen, N Woike, A Egas, G van Osch, E van Maarse, K Messier, A Chan, J Thies, L Creemers Prolonged inhibition of inflammation in osteoarthritis by triamcinolone acetonide released from a polyester amide microsphere platform J Control Release, 2017-03-09;0(0):. 2017-03-09 [PMID: 28284832] (Human)		Human
L Subedi, E Ji, D Shin, J Jin, JH Yeo, SY Kim Equol, a Dietary Daidzein Gut Metabolite Attenuates Microglial Activation and Potentiates Neuroprotection In Vitro Nutrients, 2017-02-27;9(3):. 2017-02-27 [PMID: 28264445] (Mouse)		Mouse
M Fang, Y Li, K Huang, S Qi, J Zhang, W Zgodzinski, M Majewski, G Wallner, S Gozdz, P Macek, A Kowalik, M Pasiarski, E Grywalska, L Vatan, N Nagarsheth, W Li, L Zhao, I Kryczek, G Wang, Z Wang, W Zou, L Wang IL-33 promotes colon cancer cell stemness via JNK activation and macrophage recruitment Cancer Res, 2017-03-01;0(0):. 2017-03-01 [PMID: 28249897] (Human)		Human
LY Lu, F Loi, K Nathan, TH Lin, J Pajarinen, E Gibon, A Nabeshima, L Cordova, E Jämsen, Z Yao, SB Goodman Pro-inflammatory M1 macrophages promote osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway J. Orthop. Res, 2017-03-13;0(0):. 2017-03-13 [PMID: 28248001] (Mouse)		Mouse
HL Tuan Anh, DC Kim, W Ko, TM Ha, NX Nhiem, PH Yen, BH Tai, LH Truong, VN Long, T Gioi, T Hong Quang, CV Minh, H Oh, YC Kim, PV Kiem Anti-inflammatory coumarins from Paramignya trimera Pharm Biol, 2017-12-01;55(1):1195-1201. 2017-12-01 [PMID: 28245363] (Mouse)		Mouse
A Acheva, G Schettino, KM Prise Pro-inflammatory Signaling in a 3D Organotypic Skin Model after Low LET Irradiation-NF-?B, COX-2 Activation, and Impact on Cell Differentiation Front Immunol, 2017-02-10;8(0):82. 2017-02-10 [PMID: 28239377] (Mouse)		Mouse
M Kim, HJ Lee, A Randy, JH Yun, SR Oh, CW Nho Stellera chamaejasme and its constituents induce cutaneous wound healing and anti-inflammatory activities Sci Rep, 2017-02-21;7(0):42490. 2017-02-21 [PMID: 28220834] (Human)		Human
J Lee, YH Nho, SK Yun, YS Hwang Use of ethanol extracts of Terminalia chebula to prevent periodontal disease induced by dental plaque bacteria BMC Complement Altern Med, 2017-02-16;17(1):113. 2017-02-16 [PMID: 28202081] (Human, Mouse)		Human, Mouse
C Herz, HT Tran, MR Márton, R Maul, S Baldermann, M Schreiner, E Lamy Evaluation of an Aqueous Extract from Horseradish Root (Armoracia rusticana Radix) against Lipopolysaccharide-Induced Cellular Inflammation Reaction Evid Based Complement Alternat Med, 2017-01-15;2017(0):1950692. 2017-01-15 [PMID: 28182113] (Human)		Human
A Sapkota, BP Gaire, KS Cho, SJ Jeon, OW Kwon, DS Jang, SY Kim, JH Ryu, JW Choi Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation PLoS ONE, 2017-02-08;12(2):e0171479. 2017-02-08 [PMID: 28178289] (Mouse)		Mouse
SY Kim, SM Park, M Hwangbo, JR Lee, SH Byun, SK Ku, IJ Cho, SC Kim, SY Jee, SJ Park Cheongsangbangpung-tang ameliorated the acute inflammatory response via the inhibition of NF-?B activation and MAPK phosphorylation BMC Complement Altern Med, 2017-01-13;17(1):46. 2017-01-13 [PMID: 28086859] (Mouse)		Mouse
H Lee, M Lee, Y Lee, S Choi, J Yang Chondrocyte-derived extracellular matrix suppresses pathogenesis of human pterygium epithelial cells by blocking the NF-?B signaling pathways Mol. Vis, 2016-12-24;22(0):1490-1502. 2016-12-24 [PMID: 28050122] (Human)		Human
Anti-Neuroinflammatory ent-Kaurane Diterpenoids from Pteris multifida Roots Molecules, 2016-12-26;22(1):. 2016-12-26 [PMID: 28035965] (Mouse)		Mouse
Byoung-Man Kang Anti-inflammatory effect of tricin isolated from Alopecurus aequalis Sobol. on the LPS-induced inflammatory response in RAW 264.7 cells Int. J. Mol. Med, 2016-09-30;38(5):1614-1620. 2016-09-30 [PMID: 28025993] (Mouse)		Mouse
Jisang Park Fucoidan inhibits LPS-induced inflammation in vitro and during the acute response in vivo Int. Immunopharmacol, 2016-12-14;43(0):91-98. 2016-12-14 [PMID: 27987467] (Mouse)		Mouse
The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection PLoS ONE, 2016-12-15;11(12):e0168102. 2016-12-15 [PMID: 27977732] (Human)		Human
Jun Lu Acupuncture ameliorates inflammatory response in a chronic unpredictable stress rat model of depression Brain Res. Bull, 2016-11-30;0(0):. 2016-11-30 [PMID: 27915092] (Rat)		Rat
Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism Sci Rep, 2016-12-02;6(0):38308. 2016-12-02 [PMID: 27910911] (Human)		Human
Prostaglandin E2, trace elements and levels of oxidative processes in spontaneous miscarriages Eur Rev Med Pharmacol Sci, 2016-11-01;20(22):4786-4790. 2016-11-01 [PMID: 27906421] (Human)		Human
Li Chang-Qing Piperine attenuates lipopolysaccharide (LPS)-induced inflammatory responses in BV2 microglia Int. Immunopharmacol., 2016-11-19;42(0):44-48. 2016-11-19 [PMID: 27875748] (Mouse)		Mouse
Controlled Release of Interleukin-1 Receptor Antagonist from Hyaluronic Acid-Chitosan Microspheres Attenuates Interleukin-1?-Induced Inflammation and Apoptosis in Chondrocytes Biomed Res Int, 2016-10-30;2016(0):6290957. 2016-10-30 [PMID: 27872853] (Rat)		Rat
MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis Proc. Natl. Acad. Sci. U.S.A., 2016-11-21;113(49):E7917-E7926. 2016-11-21 [PMID: 27872288] (Mouse)		Mouse
Yoonsook Kim Oryza sativa (Rice) Hull Extract Inhibits Lipopolysaccharide-Induced Inflammatory Response in RAW264.7 Macrophages by Suppressing Extracellular Signal-regulated Kinase, c-Jun N-terminal Kinase, and Nuclear Factor-?B Activation Pharmacogn Mag, 2016-10-01;12(48):295-301. 2016-10-01 [PMID: 27867272] (Mouse)		Mouse
Topical Treatment With Bromfenac Reduces Retinal Gliosis and Inflammation After Optic Nerve Crush Invest. Ophthalmol. Vis. Sci., 2016-11-01;57(14):6098-6106. 2016-11-01 [PMID: 27832276] (Rat)		Rat
Amy L McNulty Matrix Metalloproteinase Activity and Prostaglandin E2 are Elevated in the Synovial Fluid of Meniscus Tear Patients Connect. Tissue Res., 2016-11-04;0(0):. 2016-11-04 [PMID: 27813662] (Human)		Human
Farshid Guilak CRISPR/Cas9 editing of induced pluripotent stem cells for engineering inflammation-resistant tissues Arthritis & rheumatology, 2017-03-31;0(0):. 2017-03-31 [PMID: 27813286] (Mouse)		Mouse
Indoleamine 2,3-Dioxygenase Is Not a Pivotal Regulator Responsible for Suppressing Allergic Airway Inflammation through Adipose-Derived Stem Cells PLoS ONE, 2016-11-03;11(11):e0165661. 2016-11-03 [PMID: 27812173] (Mouse)		Mouse
Ines Ambite, Manoj Puthia, Karoly Nagy, Caterina Cafaro, Aftab Nadeem, Daniel S C Butler, Gustav Rydström, Nina A Filenko, Björn Wullt, Thomas Miethke, Catharina Svanborg Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets. PloS Pathogens, 2016-10-12;0(0):1553-7374. 2016-10-12 [PMID: 27732661] (Human)		Human
The role of extracellular vesicle and tunneling nanotube-mediated intercellular cross-talk between mesenchymal stem cells and human peripheral T cells Stem Cells Dev, 2016-10-04;0(0):. 2016-10-04 [PMID: 27596268] (Human)		Human
24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats PLoS ONE, 2016-08-30;11(8):e0161782. 2016-08-30 [PMID: 27575371] (Rat)		Rat
Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells Int J Mol Sci, 2016-08-19;17(8):. 2016-08-19 [PMID: 27548147] (Human)		Human
S Danesh Mes, J Sharbati, R Einspanier, C Gabler mRNA expression pattern of selected candidate genes differs in bovine oviductal epithelial cells in vitro compared with the in vivo state and during cell culture passages Reprod. Biol. Endocrinol, 2016-08-15;14(1):44. 2016-08-15 [PMID: 27526775] (Bovine)		Bovine
Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation Sci Rep, 2016-07-26;6(0):30263. 2016-07-26 [PMID: 27457881] (Human)		Human
Julia Hoffmann Anti-Inflammatory Effects of Agrimoniin-Enriched Fractions of Potentilla erecta Molecules, 2016-06-18;21(6):. 2016-06-18 [PMID: 27322232] (Human)		Human
Chan-Mi Lee Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts Cell Biosci, 2016-06-16;6(0):43. 2016-06-16 [PMID: 27313839] (Human)		Human
Mendes R, Pamuk F Endothelial Cell Response to Fusobacterium nucleatum. Infect Immun, 2016-06-23;84(7):2141-8. 2016-06-23 [PMID: 27185790] (Human)		Human
S Bruno, C Grange, M Tapparo, C Pasquino, R Romagnoli, E Dametto, A Amoroso, C Tetta, G Camussi Human Liver Stem Cells Suppress T-Cell Proliferation, NK Activity, and Dendritic Cell Differentiation Stem Cells Int, 2016-04-04;2016(0):8468549. 2016-04-04 [PMID: 27127520] (Human)		Human
S Arancibia, A Barrientos, J Torrejón, A Escobar, CJ Beltrán Copper oxide nanoparticles recruit macrophages and modulate nitric oxide, proinflammatory cytokines and PGE2 production through arginase activation Nanomedicine (Lond), 2016-04-15;0(0):. 2016-04-15 [PMID: 27079258] (Mouse)		Mouse
DC Kim, KH Cho, W Ko, CS Yoon, JH Sohn, JH Yim, YC Kim, H Oh Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus Aspergillus sp. SF-6354 via up-Regulation of Heme Oxygenase-1 in Murine Hippocampal and Microglial Cell Lines Int J Mol Sci, 2016-04-08;17(4):. 2016-04-08 [PMID: 27070586] (Mouse)		Mouse
A Malecka, Q Wang, S Shah, RV Sutavani, I Spendlove, JM Ramage, J Greensmith, HA Franks, MJ Gough, A Saalbach, PM Patel, AM Jackson Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation J Leukoc Biol, 2016-04-05;0(0):. 2016-04-05 [PMID: 27049023] (Human)		Human
Gwendolyn Sowa NF-?B Signaling Pathway in Controlling Intervertebral Disk Cell Response to Inflammatory and Mechanical Stressors Phys Ther, 2016-02-18;96(5):704-11. 2016-02-18 [PMID: 26893504] (Rabbit)		Rabbit
Lee S, Yi J, Bae W, Lee S, Cha H, Kim E Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells. PLoS ONE, 2016-01-20;11(1):e0146708. 2016-01-20 [PMID: 26789270] (Human)		Human
Clark K, Kol A, Shahbenderian S, Granick J, Walker N, Borjesson D Canine and Equine Mesenchymal Stem Cells Grown in Serum Free Media Have Altered Immunophenotype. Stem Cell Rev, 2016-04-01;12(2):245-56. 2016-04-01 [PMID: 26638159] (Canine)		Canine
Marentette J, Hurst R, McHowat J Impaired Expression of Prostaglandin E2 (PGE2) Synthesis and Degradation Enzymes during Differentiation of Immortalized Urothelial Cells from Patients with Interstitial Cystitis/Painful Bladder Syndrome. PLoS ONE, 2015-06-09;10(6):e0129466. 2015-06-09 [PMID: 26057882] (Human)		Human
Li P, Shan J, Chen X, Zhang D, Su L, Huang X, Yu B, Zhi Q, Li C, Wang Y, Tomei S, Cai Q, Ji J, Li J, Chouchane L, Yu Y, Sun F, Xu Z, Liu B, Zhu Z Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment. Cell Res, 2015-04-28;25(5):588-603. 2015-04-28 [PMID: 25916550] (Human)		Human
Almeida C, Andrade-Oliveira V, Camara N, Jacysyn J, Faquim-Mauro E Crotoxin from Crotalus durissus terrificus is able to down-modulate the acute intestinal inflammation in mice. PLoS ONE, 2015-04-08;10(4):e0121427. 2015-04-08 [PMID: 25853847] (Mouse)		Mouse
Hinden L, Shainer R, Almogi-Hazan O, Or R Ex Vivo Induced Regulatory Human/Murine Mesenchymal Stem Cells as Immune Modulators. Stem Cells, 2015-05-13;33(7):2256-67. 2015-05-13 [PMID: 25850816] (Mouse)		Mouse
Arab H, Salama S, Omar H, Arafa E, Maghrabi I Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions. PLoS ONE, 2015-03-30;10(3):e0122417. 2015-03-30 [PMID: 25821971] (Rat)		Rat
The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2. Sci Rep, 2015-03-04;5(0):8713. 2015-03-04 [PMID: 25736907] (Rat)		Rat
Gu , Wen, Song , Lin, Li , Xiao-Min, Wang , Di, Guo , Xue-Jun, Xu , Wei-Guo Mesenchymal stem cells alleviate airway inflammation and emphysema in COPD through down-regulation of cyclooxygenase-2 via p38 and ERK MAPK pathways. Sci Rep, 2015-03-04;5(0):8733. 2015-03-04 [PMID: 25736434] (Rat)		Rat
Maninchedda U, Lepage O, Gangl M, Hilairet S, Remandet B, Meot F, Penarier G, Segard E, Cortez P, Jorgensen C, Steinberg R Development of an equine groove model to induce metacarpophalangeal osteoarthritis: a pilot study on 6 horses. PLoS ONE, 2015-02-13;10(2):e0115089. 2015-02-13 [PMID: 25680102] (Equine)		Equine
Kim K, Cui X, Lee D, Ko W, Sohn J, Yim J, An R, Kim Y, Oh H Inhibitory effects of benzaldehyde derivatives from the marine fungus Eurotium sp. SF-5989 on inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages. Int J Mol Sci, 2014-12-19;15(12):23749-65. 2014-12-19 [PMID: 25535073] (Mouse)		Mouse
Xu X, Lan W, Jin X, Wang B, Yan H, Chen X, Lai X, Zhang L, Zhang X, Li Z Regulated expression of PTPRJ by COX-2/PGE2 axis in endothelial cells. PLoS ONE, 2014-12-22;9(12):e114996. 2014-12-22 [PMID: 25532119] (Human)		Human
Lin C, Lee C, Chang Y, Wang H, Chen C, Chen Y Pheophytin a inhibits inflammation via suppression of LPS-induced nitric oxide synthase-2, prostaglandin E2, and interleukin-1beta of macrophages. Int J Mol Sci, 2014-12-09;15(12):22819-34. 2014-12-09 [PMID: 25501336] (Mouse)		Mouse
Zhang , Min, Wang , Fenglan, Chong , Yutian, Tai , Qiang, Zhao , Qiyi, Zheng , Yubao, Peng , Liang, Lin , Shumei, Gao , Zhiliang Liver myofibroblasts from hepatitis B related liver failure patients may regulate natural killer cell function via PGE2. J Transl Med, 2014-11-04;12(1):308. 2014-11-04 [PMID: 25367326] (Human)		Human
Chowdhury B, David A, Thrasivoulou C, Becker D, Bader D, Chowdhury T Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane. Placenta, 2014-09-19;35(12):1057-64. 2014-09-19 [PMID: 25280972] (Human)		Human
Bowers L, Maximo I, Brenner A, Beeram M, Hursting S, Price R, Tekmal R, Jolly C, deGraffenried L NSAID use reduces breast cancer recurrence in overweight and obese women: role of prostaglandin-aromatase interactions. Cancer Res, 2014-08-15;74(16):4446-57. 2014-08-15 [PMID: 25125682] (Human)		Human
Yu K, Lee J, Kim H, Hong I, Choi S, Seo Y, Kang I, Kim J, Lee B, Lee S, Kurtz A, Seo K, Kang K A p38 MAPK-mediated alteration of COX-2/PGE2 regulates immunomodulatory properties in human mesenchymal stem cell aging. PLoS ONE, 2014-08-04;9(8):e102426. 2014-08-04 [PMID: 25090227] (Human)		Human
Li J, Li F, Wei D, Jia W, Kang J, Stefanovic-Racic M, Dai Y, Zhao A Endogenous omega-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice. Mol Endocrinol, 2014-06-30;28(8):1316-28. 2014-06-30 [PMID: 24978197] (Mouse)		Mouse
Otte A, Rauprich F, von der Ohe J, Hillemanns P, Hass R Interference of Ca(2)(+) with the proliferation of SCCOHT-1 and ovarian adenocarcinoma cells. Int J Oncol, 2014-06-24;45(3):1151-8. 2014-06-24 [PMID: 24969518] (Human)		Human
Annamanedi M, Kalle A Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1. PLoS ONE, 2014-06-20;9(6):e99285. 2014-06-20 [PMID: 24950067] (Mouse)		Mouse
Dang , Shipeng, Xu , Huanbai, Xu , Congfeng, Cai , Wei, Li , Qian, Cheng , Yiji, Jin , Min, Wang , Ru-Xing, Peng , Yongde, Zhang , Yi, Wu , Changpin, He , Xiaozhou, Wan , Bing, Zhang , Yanyun Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis. Autophagy, 2014-05-14;10(7):1301-15. 2014-05-14 [PMID: 24905997] (Mouse)		Mouse
Huang B, Lin C, Chen Y, Kao S Anti-inflammatory effects of Perilla frutescens leaf extract on lipopolysaccharide-stimulated RAW264.7 cells. Mol Med Rep, 2014-06-05;10(2):1077-83. 2014-06-05 [PMID: 24898576] (Mouse)		Mouse
Roeder E, Henrionnet C, Goebel J, Gambier N, Beuf O, Grenier D, Chen B, Vuissoz P, Gillet P, Pinzano A Dose-response of superparamagnetic iron oxide labeling on mesenchymal stem cells chondrogenic differentiation: a multi-scale in vitro study. PLoS ONE, 2014-05-30;9(5):e98451. 2014-05-30 [PMID: 24878844] (Human)		Human
Yuan , Zhihong, Mehta , Hiren J, Mohammed , Kamal, Nasreen , Najmunis, Roman , Robert, Brantly , Mark, Sadikot , Ruxana T TREM-1 is induced in tumor associated macrophages by cyclo-oxygenase pathway in human non-small cell lung cancer. PLoS ONE, 2014-05-19;9(5):e94241. 2014-05-19 [PMID: 24842612] (Human)		Human
Sui Y, Hogg A, Wang Y, Frey B, Yu H, Xia Z, Venzon D, McKinnon K, Smedley J, Gathuka M, Klinman D, Keele B, Langermann S, Liu L, Franchini G, Berzofsky J Vaccine-induced myeloid cell population dampens protective immunity to SIV. J Clin Invest, 2014-05-16;124(6):2538-49. 2014-05-16 [PMID: 24837435] (Primate - Macaca mulatta (Rhesus Macaque))		Primate - Macaca mulatta (Rhesus Macaque)
Arab H, Al-Shorbagy M, Abdallah D, Nassar N Telmisartan attenuates colon inflammation, oxidative perturbations and apoptosis in a rat model of experimental inflammatory bowel disease. PLoS ONE, 2014-05-15;9(5):e97193. 2014-05-15 [PMID: 24831514] (Rat)		Rat
Schneider B, Behrends J, Hagens K, Harmel N, Shayman J, Schaible U Lysosomal phospholipase A2: a novel player in host immunity to Mycobacterium tuberculosis. Eur J Immunol, 2014-06-11;44(8):2394-404. 2014-06-11 [PMID: 24825529] (Mouse)		Mouse
Ren G, Hu J, Wang R, Han W, Zhao M, Zhou G, Zhang C, Zhang Z Rapamycin inhibits Toll-like receptor 4-induced pro-oncogenic function in head and neck squamous cell carcinoma. Oncol Rep, 2014-04-11;31(6):2804-10. 2014-04-11 [PMID: 24737049] (Human)		Human
Chatterjee N, Das S, Bose D, Banerjee S, Jha T, Saha K Leishmanial lipid suppresses the bacterial endotoxin-induced inflammatory response with attenuation of tissue injury in sepsis. J Leukoc Biol, 2014-04-02;96(2):325-36. 2014-04-02 [PMID: 24696356] (Mouse)		Mouse
Aslan M, Aslan I, Ozcan F, Eryilmaz R, Ensari C, Bilecik T A pilot study investigating early postoperative changes of plasma polyunsaturated fatty acids after laparoscopic sleeve gastrectomy. Lipids Health Dis, 2014-04-03;13(0):62. 2014-04-03 [PMID: 24694037] (Human)		Human
Mogami , Haruta, Keller , Patrick, Shi , Haolin, Word , R Ann Effect of thrombin on human amnion mesenchymal cells, mouse fetal membranes, and preterm birth. J Biol Chem, 2014-03-20;289(19):13295-307. 2014-03-20 [PMID: 24652285] (Human)		Human
Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, Wang Q, Cao X Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation. J Biol Chem, 2014-03-13;289(16):11522-35. 2014-03-13 [PMID: 24627480] (Mouse)		Mouse
Luna-Gomes T, Filardy A, Rocha J, Decote-Ricardo D, LaRocque-de-Freitas I, Morrot A, Bozza P, Castro-Faria-Neto H, DosReis G, Nunes M, Freire-de-Lima C Neutrophils increase or reduce parasite burden in Trypanosoma cruzi-infected macrophages, depending on host strain: role of neutrophil elastase. PLoS ONE, 2014-03-05;9(3):e90582. 2014-03-05 [PMID: 24599360] (Mouse)		Mouse
Zhang M, Ye Y, Wang F, Zhu J, Zhao Q, Zheng Y, Gu Y, Xie C, Huang Z, Tai Q, Chong Y, Gao Z Liver myofibroblasts up-regulate monocyte CD163 expression via PGE2 during hepatitis B induced liver failure. 2014-03-06;0(0):. 2014-03-06 [PMID: 24597777] (Human)		Human
Yamahara , Kenichi, Harada , Kazuhiko, Ohshima , Makiko, Ishikane , Shin, Ohnishi , Shunsuke, Tsuda , Hidetosh, Otani , Kentaro, Taguchi , Akihiko, Soma , Toshihir, Ogawa , Hiroyasu, Katsuragi , Shinji, Yoshimatsu , Jun, Harada-Shiba , Mariko, Kangawa , Kenji, Ikeda , Tomoaki Comparison of angiogenic, cytoprotective, and immunosuppressive properties of human amnion- and chorion-derived mesenchymal stem cells. PLoS ONE, 2014-02-14;9(2):e88319. 2014-02-14 [PMID: 24551087] (Human)		Human
Ebeling , Sandra, Naumann , Katrin, Pollok , Simone, Wardecki , Tina, Vidal-Y-Sy , Sabine, Nascimento , Juliana, Boerries , Melanie, Schmidt , Gudula, Brandner , Johanna, Merfort , Irmgard From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract. PLoS ONE, 2014-01-22;9(1):e86147. 2014-01-22 [PMID: 24465925] (Human)		Human
Carrade Holt D, Wood J, Granick J, Walker N, Clark K, Borjesson D Equine mesenchymal stem cells inhibit T cell proliferation through different mechanisms depending on tissue source. Stem Cells Dev, 2014-03-04;23(11):1258-65. 2014-03-04 [PMID: 24438346] (Equine)		Equine
Harmel E, Grenier E, Bendjoudi Ouadda A, El Chebly M, Ziv E, Beaulieu J, Sane A, Spahis S, Laville M, Levy E AMPK in the small intestine in normal and pathophysiological conditions. Endocrinology, 2014-01-01;155(3):873-88. 2014-01-01 [PMID: 24424053] (Rat)		Rat
Chen C, Akiyama K, Yamaza T, You Y, Xu X, Li B, Zhao Y, Shi S Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. EMBO Mol Med, 2014-01-08;6(3):322-34. 2014-01-08 [PMID: 24401839] (Human)		Human
Jung , Eunsun, Lee , Jung-A, Shin , Seoungwo, Roh , Kyung-Ba, Kim , Jang-Hyu, Park , Deokhoon Madecassoside inhibits melanin synthesis by blocking ultraviolet-induced inflammation. Molecules, 2013-12-16;18(12):15724-36. 2013-12-16 [PMID: 24352025] (Human)		Human
Conforti A, Biagini S, Del Bufalo F, Sirleto P, Angioni A, Starc N, Li Pira G, Moretta F, Proia A, Contoli B, Genovese S, Ciardi C, Avanzini M, Rosti V, Lo-Coco F, Locatelli F, Bernardo M Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic leukemia. PLoS ONE, 2013-11-07;8(11):e76989. 2013-11-07 [PMID: 24244271] (Human)		Human
Aslan M, Ozcan F, Aslan I, Yucel G LC-MS/MS analysis of plasma polyunsaturated fatty acids in type 2 diabetic patients after insulin analog initiation therapy. Lipids Health Dis, 2013-11-06;12(0):169. 2013-11-06 [PMID: 24195588] (Human)		Human
Sidney L, Kirkham G, Buttery L Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma. Stem Cells Dev, 2014-01-23;23(6):605-17. 2014-01-23 [PMID: 24192281] (Mouse)		Mouse
Delaine-Smith , Robin M, Sittichokechaiwut , Anuphan, Reilly , Gwendole Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts. FASEB J, 2013-10-04;28(1):430-9. 2013-10-04 [PMID: 24097311] (Mouse)		Mouse
Wan , Rong, Jin , Lai, Zhu , Chao, Liu , Yunxin, Li , Li, Guo , Rui, Li , Shengnan Sex difference in urocortin production is contributory to the gender disparity in a rat model of vasculitis induced by sodium laurate. Endocrinology, 2013-09-24;154(12):4663-74. 2013-09-24 [PMID: 24064363] (Rat)		Rat
Theoduloz , Cristina, Bravo , Ivanna, Pertino , Mariano, Schmeda-Hirschmann , Guillerm Diterpenylquinone hybrids: synthesis and assessment of gastroprotective mechanisms of action in human cells. Molecules, 2013-09-10;18(9):11044-66. 2013-09-10 [PMID: 24025455] (Human)		Human
Iachininoto M, Nuzzolo E, Bonanno G, Mariotti A, Procoli A, Locatelli F, De Cristofaro R, Rutella S Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells. Molecules, 2013-08-22;18(9):10132-45. 2013-08-22 [PMID: 23973990] (Human)		Human
Shin S, Jung E, Kim S, Kim J, Kim E, Lee J, Park D Antagonizing effects and mechanisms of afzelin against UVB-induced cell damage. PLoS ONE, 2013-04-23;8(4):e61971. 2013-04-23 [PMID: 23626759] (Human)		Human
Manferdini C, Maumus M, Gabusi E, Piacentini A, Filardo G, Peyrafitte J, Jorgensen C, Bourin P, Fleury-Cappellesso S, Facchini A, Noel D, Lisignoli G Adipose-derived mesenchymal stem cells exert antiinflammatory effects on chondrocytes and synoviocytes from osteoarthritis patients through prostaglandin E2. Arthritis Rheum, 2013-05-01;65(5):1271-81. 2013-05-01 [PMID: 23613363] (Human)		Human
Matysiak , Mariola, Fortak-Michalska , Maria, Szymanska , Bozena, Orlowski , Wojciech, Jurewicz , Anna, Selmaj , Krzyszto MicroRNA-146a negatively regulates the immunoregulatory activity of bone marrow stem cells by targeting prostaglandin E2 synthase-2. J Immunol, 2013-04-15;190(10):5102-9. 2013-04-15 [PMID: 23589616] (Mouse)		Mouse
Mace T, Ameen Z, Collins A, Wojcik S, Mair M, Young G, Fuchs J, Eubank T, Frankel W, Bekaii-Saab T, Bloomston M, Lesinski G Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner. Cancer Res, 2013-03-20;73(10):3007-18. 2013-03-20 [PMID: 23514705] (Human)		Human
Herranz S, Traves P, Luque A, Hortelano S Role of the tumor suppressor ARF in macrophage polarization: Enhancement of the M2 phenotype in ARF-deficient mice. Oncoimmunology, 2012-11-01;1(8):1227-1238. 2012-11-01 [PMID: 23243586] (Mouse)		Mouse
Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice. J Biol Chem, 2012-11-26;288(3):1953-66. 2012-11-26 [PMID: 23184961] (Human)		Human
Zong Y, Sun L, Liu B, Deng Y, Zhan D, Chen Y, He Y, Liu J, Zhang Z, Sun J, Lu D Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells. PLoS ONE, 2012-08-31;7(8):e44107. 2012-08-31 [PMID: 22952890] (Mouse)		Mouse
Ylostalo J, Bartosh T, Coble K, Prockop D Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype. Stem Cells, 2012-10-01;30(10):2283-96. 2012-10-01 [PMID: 22865689] (Mouse)		Mouse
Wang JH, Shih KS, Liou JP, Wu YW, Chang AS, Wang KL, Tsai CL, Yang CR Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model. PLoS ONE, 2012-02-16;7(2):e31368. 2012-02-16 [PMID: 22359588] (Human)		Human
Liu L, Cao Z, Chen J Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling. J. Biol. Chem., 2012-02-16;287(15):11899-910. 2012-02-16 [PMID: 22343630] (Human)		Human
Gottfries J, Melgar S, Michaelsson E Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease. PLoS ONE, 2012-01-18;7(1):e30005. 2012-01-18 [PMID: 22279558] (Mouse)		Mouse
Rai MF, Graeve T, Twardziok S, Schmidt MF Evidence for regulated interleukin-4 expression in chondrocyte-scaffolds under in vitro inflammatory conditions. PLoS ONE, 2011-10-03;6(10):e25749. 2011-10-03 [PMID: 21991344] (Canine)		Canine
Abdelrazik H, Spaggiari GM, Chiossone L, Moretta L Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T- and NK-cell proliferation and function. Eur. J. Immunol., 2011-10-18;41(11):3281-90. 2011-10-18 [PMID: 21874650] (Human)		Human
Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI Serotonin activates dendritic cell function in the context of gut inflammation. Am. J. Pathol., 2011-02-01;178(2):662-71. 2011-02-01 [PMID: 21281798] (Mouse)		Mouse
Oliveira CJ, Sa-Nunes A, Francischetti IM, Carregaro V, Anatriello E, Silva JS, Santos IK, Ribeiro JM, Ferreira BR Deconstructing tick saliva: non-protein molecules with potent immunomodulatory properties. J. Biol. Chem., 2011-01-26;286(13):10960-9. 2011-01-26 [PMID: 21270122] (Mouse, Tick)		Mouse, Tick
Zhao Z, Liu N, Huang J, Lu PH, Xu XM Inhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell death. J. Neurochem., 2011-01-19;116(6):1057-65. 2011-01-19 [PMID: 21182525] (Rat)		Rat
Verma S, Kumar M, Nerurkar VR Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes. J. Gen. Virol., 2010-11-24;92(0):507-15. 2010-11-24 [PMID: 21106803] (Human)		Human
Nakajima S, Honda T, Sakata D, Egawa G, Tanizaki H, Otsuka A, Moniaga CS, Watanabe T, Miyachi Y, Narumiya S, Kabashima K Prostaglandin I2-IP signaling promotes Th1 differentiation in a mouse model of contact hypersensitivity. J. Immunol., 2010-04-16;184(10):5595-603. 2010-04-16 [PMID: 20400695] (Mouse)		Mouse
Rydkina E, Turpin LC, Sahni SK Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms. Infect. Immun., 2010-04-12;78(6):2599-606. 2010-04-12 [PMID: 20385756] (Human)		Human
Niwa S, Urtz N, Baumruker T, Billich A, Bornancin F Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1-/- mice. Lipids Health Dis, 2010-01-06;9(0):1. 2010-01-06 [PMID: 20053284] (Mouse)		Mouse
Degagne E, Grbic DM, Dupuis AA, Lavoie EG, Langlois C, Jain N, Weisman GA, Sevigny J, Gendron FP P2Y2 receptor transcription is increased by NF-kappa B and stimulates cyclooxygenase-2 expression and PGE2 released by intestinal epithelial cells. J. Immunol., 2009-09-04;183(7):4521-9. 2009-09-04 [PMID: 19734210] (Human)		Human
Park DS, Huh JE, Baek YH Therapeutic effect of Aralia cordata extracts on cartilage protection in collagenase-induced inflammatory arthritis rabbit model. J Ethnopharmacol, 2009-07-18;125(2):207-17. 2009-07-18 [PMID: 19619632] (Rabbit)		Rabbit
Luna C, Li G, Qiu J, Challa P, Epstein DL, Gonzalez P Extracellular release of ATP mediated by cyclic mechanical stress leads to mobilization of AA in trabecular meshwork cells. Invest. Ophthalmol. Vis. Sci., 2009-07-15;50(12):5805-10. 2009-07-15 [PMID: 19608543] (Porcine)		Porcine
Campeau PM, Rafei M, Boivin MN, Sun Y, Grabowski GA, Galipeau J Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. Blood, 2009-07-08;114(15):3181-90. 2009-07-08 [PMID: 19587377] (Human)		Human
Yamaguchi T, Takada Y, Maruyama K, Shimoda K, Arai Y, Nango N, Kosaki N, Takaishi H, Toyama Y, Matsuo K Fra-1/AP-1 impairs inflammatory responses and chondrogenesis in fracture healing. J. Bone Miner. Res., 2009-12-01;24(12):2056-65. 2009-12-01 [PMID: 19558315] (Mouse)		Mouse
Souza Mdo C, Beserra AM, Martins DC, Real VV, Santos RA, Rao VS, Silva RM, Martins DT In vitro and in vivo anti-Helicobacter pylori activity of Calophyllum brasiliense Camb. J Ethnopharmacol, 2009-03-27;123(3):452-8. 2009-03-27 [PMID: 19501278] (Rat)		Rat
Highfill SL, Kelly RM, O'Shaughnessy MJ, Zhou Q, Xia L, Panoskaltsis-Mortari A, Taylor PA, Tolar J, Blazar BR Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming. Blood, 2009-05-20;114(3):693-701. 2009-05-20 [PMID: 19458354] (Mouse)		Mouse
Cheon MS, Yoon T, Lee do Y, Choi G, Moon BC, Lee AY, Choo BK, Kim HK Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages. J Ethnopharmacol, 2009-02-03;122(3):473-7. 2009-02-03 [PMID: 19429315] (Mouse)		Mouse
Sanchez-Lemus E, Benicky J, Pavel J, Saavedra JM In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat pituitary gland. Brain Behav. Immun., 2009-05-07;23(7):945-57. 2009-05-07 [PMID: 19427376] (Rat)		Rat
Lee SH, Kim MH, Han HJ Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: involvement of Notch, Wnt, and HIF-1alpha. Am. J. Physiol., Cell Physiol., 2009-04-01;297(1):C207-16. 2009-04-01 [PMID: 19339510] (Mouse)		Mouse
Gadgeel SM, Ali S, Philip PA, Wozniak A, Sarkar FH Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines. Cancer, 2009-05-15;115(10):2165-76. 2009-05-15 [PMID: 19288574] (Human)		Human
Mayer K, Kiessling A, Ott J, Schaefer MB, Hecker M, Henneke I, Schulz R, Gunther A, Wang J, Wu L, Roth J, Seeger W, Kang JX Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids. Am. J. Respir. Crit. Care Med., 2009-01-08;179(6):474-83. 2009-01-08 [PMID: 19136374] (Mouse)		Mouse
Castellano G, Malaponte G, Mazzarino MC, Figini M, Marchese F, Gangemi P, Travali S, Stivala F, Canevari S, Libra M Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression. Clin. Cancer Res., 2008-11-15;14(22):7470-80. 2008-11-15 [PMID: 19010864] (Human)		Human
Zhou W, Newcomb DC, Moore ML, Goleniewska K, O'Neal JF, Peebles RS Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses. J. Immunol., 2008-10-15;181(8):5360-7. 2008-10-15 [PMID: 18832692] (Mouse)		Mouse
Li Q, Guo Z, Xu X, Xia S, Cao X Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation. Eur. J. Immunol., 2008-10-01;38(10):2751-61. 2008-10-01 [PMID: 18825748] (Mouse)		Mouse
Huh JE, Baek YH, Kim YJ, Lee JD, Choi DY, Park DS Protective effects of butanol fraction from Betula Platyphyla var. japonica on cartilage alterations in a rabbit collagenase-induced osteoarthritis. J Ethnopharmacol, 2008-09-04;123(3):515-21. 2008-09-04 [PMID: 18817862] (Rabbit)		Rabbit
Reddi D, Bostanci N, Hashim A, Aduse-Opoku J, Curtis MA, Hughes FJ, Belibasakis GN Porphyromonas gingivalis regulates the RANKL-OPG system in bone marrow stromal cells. Microbes Infect., 2008-08-26;10(14):1459-68. 2008-08-26 [PMID: 18789397] (Mouse)		Mouse
Gomez-Hernandez A, Sanchez-Galan E, Ortego M, Martin-Ventura JL, Blanco-Colio LM, Tarin-Vicente N, Jimenez-Nacher JJ, Lopez-Bescos L, Egido J, Tuñón J Effect of intensive atorvastatin therapy on prostaglandin E2 levels and metalloproteinase-9 activity in the plasma of patients with non-ST-elevation acute coronary syndrome. Am. J. Cardiol., 2008-04-22;102(1):12-8. 2008-04-22 [PMID: 18572029] (Human)		Human
Pae HO, Jeong SO, Koo BS, Ha HY, Lee KM, Chung HT Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages. Biochem. Biophys. Res. Commun., 2008-04-22;371(3):361-5. 2008-04-22 [PMID: 18435907] (Mouse)		Mouse
Liotta F, Angeli R, Cosmi L, Fili L, Manuelli C, Frosali F, Mazzinghi B, Maggi L, Pasini A, Lisi V, Santarlasci V, Consoloni L, Angelotti ML, Romagnani P, Parronchi P, Krampera M, Maggi E, Romagnani S, Annunziato F Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling. Stem Cells, 2007-10-25;26(1):279-89. 2007-10-25 [PMID: 17962701] (Human)		Human
Tam CL, Hofbauer M, Towle CA Requirement for protein kinase R in interleukin-1alpha-stimulated effects in cartilage. Biochem. Pharmacol., 2007-08-07;74(11):1636-41. 2007-08-07 [PMID: 17850766] (Bovine)		Bovine
Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J. Immunol., 2007-08-01;179(3):1855-63. 2007-08-01 [PMID: 17641052] (Mouse)		Mouse
Machado RR, Soares DM, Proudfoot AE, Soares DM, Proudfoot AE, Souza GE, Souza GE CCR1 and CCR5 chemokine receptors are involved in fever induced by LPS (E. coli) and RANTES in rats. Brain Res., 2007-06-09;1161(0):21-31. 2007-06-09 [PMID: 17604006] (Rat)		Rat
Niki Y, Takaishi H, Takito J, Miyamoto T, Kosaki N, Matsumoto H, Toyama Y, Tada N Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction. J. Immunol., 2007-07-01;179(1):639-46. 2007-07-01 [PMID: 17579086] (Mouse)		Mouse
Hennerbichler A, Fermor B, Hennerbichler D, Weinberg JB, Guilak F Regional differences in prostaglandin E2 and nitric oxide production in the knee meniscus in response to dynamic compression. Biochem. Biophys. Res. Commun., 2007-05-14;358(4):1047-53. 2007-05-14 [PMID: 17517372] (Porcine)		Porcine
Nandi J, Saud B, Zinkievich JM, Palma DT, Levine RA 5-aminosalicylic acid improves indomethacin-induced enteropathy by inhibiting iNOS transcription in rats. Dig. Dis. Sci., 2007-05-15;53(1):123-32. 2007-05-15 [PMID: 17503181] (Rat)		Rat
Show All 418 Publications. Collapse Publications.

Array KGE004B

• Prostaglandin E2/PGE2 ELISAs