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PP2C beta/PPM1B Antibody (OTI3C9) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF
Clone
OTI3C9
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-73548AF350
Alexa Fluor 405
NBP2-73548AF405
Alexa Fluor 488
NBP2-73548AF488
Alexa Fluor 532
NBP2-73548AF532
Alexa Fluor 594
NBP2-73548AF594
Alexa Fluor 647
NBP2-73548AF647
Alexa Fluor 700
NBP2-73548AF700
Alexa Fluor 750
NBP2-73548AF750
Allophycocyanin
NBP2-73548APC
Allophycocyanin/Cy7
NBP2-73548APCCY7
Biotin
NBP2-73548B
CoraFluor 1
NBP2-73548CL1
DyLight 350
NBP2-73548UV
DyLight 405
NBP2-73548V
DyLight 488
NBP2-73548G
DyLight 550
NBP2-73548R
DyLight 594
NBP2-73548DL594
DyLight 650
NBP2-73548C
DyLight 680
NBP2-73548FR
DyLight 755
NBP2-73548IR
FITC
NBP2-73548F
HRP
NBP2-73548H
Janelia Fluor 525
NBP2-73548JF525
Janelia Fluor 585
NBP2-73548JF585
Janelia Fluor 635
NBP2-73548JF635
Janelia Fluor 646
NBP2-73548JF646
Janelia Fluor 669
NBP2-73548JF669
PE
NBP2-73548PE
PE/Atto594
NBP2-73548PEATT594
PE/Cy5.5
NBP2-73548PECY55
PE/Cy7
NBP2-73548PECY7
PerCP
NBP2-73548PCP
Unconjugated
NBP2-45383
mFluor Violet 450 SE
NBP2-73548MFV450
mFluor Violet 500 SE
NBP2-73548MFV500
mFluor Violet 610 SE
NBP2-73548MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-45383
Azide and BSA Free
NBP2-73548
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PP2C beta/PPM1B Antibody (OTI3C9) [Janelia Fluor® 549] Summary

Immunogen
Full length recombinant protein of human PP2C beta/PPM1B (NP_002697) produced in HEK293T cells.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
PPM1B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PP2C beta/PPM1B Antibody (OTI3C9) [Janelia Fluor® 549]

  • EC 3.1.3.16
  • MGC21657
  • PP2C beta
  • Pp2c2
  • PP2CB
  • PP2C-beta
  • PP2C-beta-X
  • PP2CBmagnesium-dependent, beta isoform
  • PPM1B
  • protein phosphatase 1B
  • Protein phosphatase 2C isoform beta
  • protein phosphatase 2C-like protein
  • protein phosphatase, Mg2+/Mn2+ dependent, 1B

Background

PPM1B is encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu
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Species: Hu
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Bioinformatics

Gene Symbol PPM1B