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PITRM1 Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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PITRM1 Antibody Summary

Immunogen
Between 987 and 1037
Assay Type
[Assay Type]
Sample Volume
[Sample Volume]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PITRM1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-citrate/phosphate pH 7 -8.
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for PITRM1 Antibody

  • EC 3.4.24
  • EC 3.4.24.-
  • hPreP
  • Metalloprotease 1
  • MGC138192
  • MGC141929
  • pitrilysin metallopeptidase 1
  • Pitrilysin metalloproteinase 1mitochondrial
  • PreP

Background

ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PITRM1