OGR1 Antibody - BSA Free Summary
Description |
Product can be stored undiluted at 4C for up to 1 month. |
Immunogen |
Synthetic 16 aa peptide from C-Terminus of human OGR1. |
Epitope |
C-Terminus |
Localization |
Cell membrane; Multipass membrane protein. |
Specificity |
Human OGR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
GPR68 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunohistochemistry-Paraffin 10 - 20 ug/ml
|
Application Notes |
. |
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Dog, Bat, Panda, Platypus (88%).
Packaging, Storage & Formulations
Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.1% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for OGR1 Antibody - BSA Free
Background
OGR1, a Lysophospholipid/Lysosphingolipid Receptor, was isolated by degenerate PCR from an ovarian cell line cDNA library. It is not expressed in normal ovary. OGR1 binds sphingosylphosporylcholine, a lipid molecule involved in cell growth and survival. Recently, OGR1 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003). OGR1 has been reported to be expressed in blood, brain, heart, kidney, lung, placenta, small intestine, spleen, and testis. ESTs have been isolated from blood, lung, and uterine libraries. Caution: OGR1 is also known as GPR12A, which is distinct from GPR12 in cluster 3851.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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