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NKCC1/SLC12A2 Antibody (915911) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
915911
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

Order Details

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NKCC1/SLC12A2 Antibody (915911) [mFluor Violet 610 SE] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human NKCC1/SLC12A2
Met1-Ser1212
Accession # P55011
Specificity
Stains NKCC1/SLC12A2 transfectants but not irrelevant transfectants in flow cytometry.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
SLC12A2
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for NKCC1/SLC12A2 Antibody (915911) [mFluor Violet 610 SE]

  • Basolateral Na-K-Cl symporter
  • BSC
  • BSC2
  • Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1
  • NKCC1
  • NKCC1MGC104233
  • SLC12A2
  • solute carrier family 12 (sodium/potassium/chloride transporters), member 2
  • solute carrier family 12 member 2

Background

Belonging to the SLC12A transporter family, NKCC1 is located on the basolateral membrane of secretory epithelia. Playing an important role in ionic balance and cell volume, NKCC1 is an electrically silent transporter system that mediates sodium, potassium and chloride transport and reabsorption. NKCC1 has interaction with OXSR1, STK39, MAPK14, UBC and RANBP2. Diseases associated with NKCC1 include hearing loss, growth failure, bleeding, torticollis and small intestinal prolapse and Bartter disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLC12A2