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Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
PCRP-NR3C2-1E3
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-26967AF350
Alexa Fluor 405
NBP3-26967AF405
Alexa Fluor 488
NBP3-26967AF488
Alexa Fluor 532
NBP3-26967AF532
Alexa Fluor 594
NBP3-26967AF594
Alexa Fluor 647
NBP3-26967AF647
Alexa Fluor 700
NBP3-26967AF700
Alexa Fluor 750
NBP3-26967AF750
Allophycocyanin
NBP3-26967APC
Biotin
NBP3-26967B
DyLight 350
NBP3-26967UV
DyLight 405
NBP3-26967V
DyLight 488
NBP3-26967G
DyLight 550
NBP3-26967R
DyLight 594
NBP3-26967DL594
DyLight 650
NBP3-26967C
DyLight 680
NBP3-26967FR
DyLight 755
NBP3-26967IR
FITC
NBP3-26967F
HRP
NBP3-26967H
Janelia Fluor 525
NBP3-26967JF525
Janelia Fluor 549
NBP3-26967JF549
Janelia Fluor 585
NBP3-26967JF585
Janelia Fluor 635
NBP3-26967JF635
Janelia Fluor 646
NBP3-26967JF646
Janelia Fluor 669
NBP3-26967JF669
PE
NBP3-26967PE
PerCP
NBP3-26967PCP
Unconjugated
NBP3-26819-100ug
mFluor Violet 450 SE
NBP3-26967MFV450
mFluor Violet 500 SE
NBP3-26967MFV500
mFluor Violet 610 SE
NBP3-26967MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-26819-100ug
Azide and BSA Free
NBP3-26967
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Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Recombinant fragment (around aa601-673) of human Mineralocorticoid R/NR3C2 protein
Localization
Nucleus
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NR3C2
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3) [CoraFluor™ 1]

  • FLJ41052
  • MGC133092
  • Mineralocorticoid R
  • mineralocorticoid receptor 1
  • mineralocorticoid receptor delta
  • MineralocorticoidR
  • MLR
  • MLRmineralocorticoid receptor
  • MRMCRaldosterone receptor
  • NR3C2
  • NR3C2VIT
  • Nuclear receptor subfamily 3 group C member 2
  • nuclear receptor subfamily 3, group C, member 2

Background

Steroid receptors are ligand dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Mineralocorticoids are a family of steroids, secreted by the adrenal cortex, necessary for the regulation of a number of metabolic processes including electrolyte regulation. These compounds exert their effect through their interaction with the mineralocorticoid receptor and that complex's subsequent association with DNA. Given the function of mineralocorticoids, it is not surprising to find that the kidney is a primary target organ for mineralocorticoids and that this organ has been shown to contain Mineralocorticoid Receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NR3C2