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MIG2/Kindlin-2 Antibody (3A3) [Alexa Fluor® 700]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, HaSpecies Glossary
Applications WB, ICC/IF, IHC, IP
Clone
3A3
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 700

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MIG2/Kindlin-2 Antibody (3A3) [Alexa Fluor® 700] Summary

Immunogen
Recombinant protein containing MIG2/Kindlin-2 (residues 218-486) (Uniprot: Q96AC1)
Localization
Cytoplasm
Specificity
Kindlin-2 (also known as Mig-2, KIND2) is an important component of cell-extracellular matrix adhesion. Kindlin-2 binds integrins and is involved in ECM adhesion, actin assembly and cell shape modulation. This monoclonal antibody recognizes kindlin-2 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
FERMT2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MIG2/Kindlin-2 Antibody (3A3) [Alexa Fluor® 700]

  • fermitin family homolog 2 (Drosophila)
  • fermitin family homolog 2
  • fermitin family member 2
  • FERMT2
  • KIND2
  • KIND2DKFZp686G11125
  • kindlin 2
  • Kindlin-2
  • MIG2
  • mig-2
  • MIG2FLJ34213
  • mitogen inducible gene 2 protein
  • Mitogen-inducible gene 2 protein
  • PH domain-containing family C member 1
  • pleckstrin homology domain containing, family C (with FERM domain) member 1
  • pleckstrin homology domain containing, family C member 1
  • Pleckstrin homology domain-containing family C member 1
  • PLEKHC1
  • PLEKHC1FLJ44462
  • UNC112
  • UNC112B

Background

Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol FERMT2