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Methionine Aminopeptidase 2/METAP2 Antibody

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Western Blot: Methionine Aminopeptidase 2/METAP2 Antibody [NBP2-84161] - WB Suggested Anti-METAP2 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human brain
Immunohistochemistry-Paraffin: Methionine Aminopeptidase 2/METAP2 Antibody [NBP2-84161] - Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. METAP2 Antibody ...read more
Western Blot: Methionine Aminopeptidase 2/METAP2 Antibody [NBP2-84161] - Host: Rabbit. Target Name: METAP2. Sample Type: Jurkat. Antibody Dilution: 1.0ug/mlMETAP2 is strongly supported by BioGPS gene expression data to ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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Methionine Aminopeptidase 2/METAP2 Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human Methionine Aminopeptidase 2/METAP2. Peptide sequence: ATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGR The peptide sequence for this immunogen was taken from within the described region.
Clonality
Polyclonal
Host
Rabbit
Gene
METAP2
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for Methionine Aminopeptidase 2/METAP2 Antibody

  • Amp2
  • eIF-2-associated p67 homolog
  • Initiation factor 2-associated 67 kDa glycoprotein
  • MAP 2
  • MAP2
  • MetAP 2
  • METAP2
  • Methionine Aminopeptidase 2
  • methionyl aminopeptidase 2
  • MNPEP
  • p67
  • p67EC 3.4.11.18
  • p67eIF2
  • Peptidase M 2

Background

METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol METAP2