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Methionine Aminopeptidase 2/METAP2 Antibody (5U2F4)

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Western Blot: Methionine Aminopeptidase 2/METAP2 Antibody (5U2F4) [NBP3-16193] - Western blot analysis of extracts of Rat testis, using Methionine Aminopeptidase 2/METAP2 Rabbit mAb (NBP3-16193) at 1:1000 dilution. ...read more
Western Blot: Methionine Aminopeptidase 2/METAP2 Antibody (5U2F4) [NBP3-16193] - Western blot analysis of extracts of various cell lines, using Methionine Aminopeptidase 2/METAP2 Rabbit mAb (NBP3-16193) at 1:1000 ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
5U2F4
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Methionine Aminopeptidase 2/METAP2 Antibody (5U2F4) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 380-478 of human Methionine Aminopeptidase 2/METAP2 (NP_006829.1). CSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
METAP2
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000 - 1:5000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 0.05% BSA, 50% glycerol, pH7.3
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Methionine Aminopeptidase 2/METAP2 Antibody (5U2F4)

  • Amp2
  • eIF-2-associated p67 homolog
  • Initiation factor 2-associated 67 kDa glycoprotein
  • MAP 2
  • MAP2
  • MetAP 2
  • METAP2
  • Methionine Aminopeptidase 2
  • methionyl aminopeptidase 2
  • MNPEP
  • p67
  • p67EC 3.4.11.18
  • p67eIF2
  • Peptidase M 2

Background

METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol METAP2