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MDC1 Antibody (P2B11) [DyLight 350]

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Product Details

Summary
Reactivity Hu, Mu, Bv, Pm-NHPSpecies Glossary
Applications WB, ICC/IF
Clone
P2B11
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

MDC1 Antibody (P2B11) [DyLight 350] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
Localization
Nucleus
Specificity
Detects approx 184kDa. This antibody recognizes MDC1 at and around the N-terminus.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MDC1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MDC1 Antibody (P2B11) [DyLight 350]

  • DKFZp781A0122
  • Em:AB023051.5
  • KIAA0170MGC166888
  • MDC1
  • mediator of DNA damage checkpoint 1
  • mediator of DNA damage checkpoint protein 1
  • mediator of DNA-damage checkpoint 1
  • NFBD1
  • NFBD1homologue to Drosophila photoreceptor protein calphotin
  • Nuclear factor with BRCT domains 1

Background

MDC1 works with H2AX to promote recruitment of repair proteins to the sites of DNA breaks and controls damage-induced cell-cycle arrest checkpoints. Cells that lack MDC1 are sensitive to ionizing radiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for MDC1 Antibody (NBP2-12890UV) (0)

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Secondary Antibodies

 

Isotype Controls

Additional MDC1 Products

Array NBP2-12890UV

Research Areas for MDC1 Antibody (NBP2-12890UV)

Find related products by research area.

Blogs on MDC1.

Further unraveling the role of gamma H2AX in DNA damage response
Our genome experiences a moderate amount of DNA damage in our cells on a daily basis.  This DNA damage can be in response to external environmental factors, or be a result of our internal metabolic processes going awry.  While normal rates of DNA ...  Read full blog post.

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Bioinformatics

Gene Symbol MDC1