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MAT1A Antibody [Janelia Fluor® 585]

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Summary
Product Discontinued
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    • Catalog Number
      NBP2-97484JF585
    • Availability
      Product Discontinued

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MAT1A Antibody [Janelia Fluor® 585] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human MAT1A fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MAT1A
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for MAT1A Antibody [Janelia Fluor® 585]

  • AdoMet synthase 1
  • adoMet synthetase 1
  • AMS1
  • MAT
  • MATA1MAT 1
  • MAT-I/III
  • Methionine adenosyltransferase 1
  • methionine adenosyltransferase I, alpha
  • Methionine adenosyltransferase I/III
  • S-adenosylmethionine synthase isoform type-1
  • S-adenosylmethionine synthetase isoform type-1
  • SAMS
  • SAMS1EC 2.5.1.6

Background

MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers, expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.

MAT1A and MAT2A antibodies are useful tools for cancer research and liver function research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MAT1A