Home » Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 » Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibodies » Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [Janelia Fluor® 549]
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Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-06855AF350
Alexa Fluor 405
NBP3-06855AF405
Alexa Fluor 488
NBP3-06855AF488
Alexa Fluor 532
NBP3-06855AF532
Alexa Fluor 594
NBP3-06855AF594
Alexa Fluor 647
NBP3-06855AF647
Alexa Fluor 700
NBP3-06855AF700
Alexa Fluor 750
NBP3-06855AF750
Biotin
NBP3-06855B
CoraFluor 1
NBP3-06855CL1
DyLight 350
NBP3-06855UV
DyLight 405
NBP3-06855V
DyLight 488
NBP3-06855G
DyLight 550
NBP3-06855R
DyLight 594
NBP3-06855DL594
DyLight 650
NBP3-06855C
DyLight 680
NBP3-06855FR
DyLight 755
NBP3-06855IR
FITC
NBP3-06855F
Janelia Fluor 525
NBP3-06855JF525
Janelia Fluor 585
NBP3-06855JF585
Janelia Fluor 635
NBP3-06855JF635
Janelia Fluor 646
NBP3-06855JF646
Janelia Fluor 669
NBP3-06855JF669
Unconjugated
NBP3-06855
mFluor Violet 450 SE
NBP3-06855MFV450
mFluor Violet 500 SE
NBP3-06855MFV500
mFluor Violet 610 SE
NBP3-06855MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-06855
BSA Free
NBP3-06855SS
BSA Free
NBP3-06855
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Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [Janelia Fluor® 549] Summary

Immunogen
Partial recombinant protein made to an internal portion of the human JMJD3 protein (amino acids 1520-1682) [UniProt O15054]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KDM6B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [Janelia Fluor® 549]

  • EC 1.14.11
  • EC 1.14.11.-
  • JmjC domain-containing protein 3
  • JMJD3
  • JMJD3lysine-specific demethylase 6B
  • jumonji domain containing 3, histone lysine demethylase
  • Jumonji domain-containing protein 3
  • KDM6B
  • KIAA0346jumonji domain containing 3
  • Lysine (K)specific Demethylase 6B
  • Lysine (K)-specific Demethylase 6B
  • Lysine demethylase 6B

Background

JMJD3 is a histone demethylase that specifically demethylates trimethylated and dimethylated 'Lys-27' of histone H3, thereby playing a central role in histone code. JMJD3 is also important for the regulation of posterior development by regulating HOX gene expression. JMJD3 is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. It has also been shown to be essential to mammalian epidermal differentiation and is upregulated in prostate cancer.

JMJD3 antibodies are useful tools for epigenetics research and specifically for histone modification studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody (NBP3-06855JF549) (0)

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Secondary Antibodies

 

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mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol KDM6B