Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [HRP] Summary
Immunogen |
Synthetic peptide made to an internal portion of the mouse JMJD3 protein (within residues 600-650). [Swiss-Prot# Q5NCY0] |
Localization |
Nucleus |
Predicted Species |
Rat (100%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
KDM6B |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Readout System |
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Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
No Preservative |
Purity |
Immunogen affinity purified |
Alternate Names for Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody [HRP]
Background
JMJD3 is a histone demethylase that specifically demethylates trimethylated and dimethylated 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development by regulating HOX gene expression. JMJD3 is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. It has shown to be essential to mammalian epidermal differentiation and is upregulated in prostate cancer.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody (NBP1-06640H) (0)
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Reviews for Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody (NBP1-06640H) (0)
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Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for Lysine (K)-specific Demethylase 6B/KDM6B/JMJD3 Antibody (NBP1-06640H). (Showing 1 - 1 of 1 FAQ).
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Your web site shows WB with HepG2 lysate. Did you try this with any mouse or rat lysate?
- We tried PC12, 3T3 and A431 cell lysates.
Secondary Antibodies
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Isotype Controls
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