Kir6.1 Antibody (S366-60)

The Kir6.1 (KCNJ8) gene is essential in membrane function as it encodes an inward-rectifier potassium channel protein that is 424 amino acids long and has a mass of nearly 48 kDA. Dysfunctions in the Kir6.1 gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). Research is investigating its role in various diseases such as retinitis, hypoxia, pancreatitis, myocardial infarction, spasticity, leiomyoma, acute myocardial infarction, and prinzmetal angina. The Kir6.1 gene plays a significant role in ATP sensitive potassium channels, SIDS susceptibility pathways, dopamine feedback into cAMP pathway, and the CFTR-dependent regulation of ion channels in airway epithelium. It interacts with other genes such as KCNJ2, ABCC8, ABCC9, and KCNJ11.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Rat, Gerbil.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publications 1 - 2 of 2.

Publications using NBP2-59324	Applications	Species
Strutynskyi RB, Strutynska NA, Piven OO et al. Upregulation of ATP-Sensitive Potassium Channels as the Potential Mechanism of Cardioprotection and Vasorelaxation Under the Action of Pyridoxal-5-Phosphate in Old Rats Journal of cardiovascular pharmacology and therapeutics 2023-11-10 [PMID: 37946524] (WB, Rat) Details: 1:1000 WB dilution	WB	Rat
Park J H, Kim D W et al. Improved HCN channels in pyramidal neurons and their new expression levels in pericytes and astrocytes in the gerbil hippocampal CA1 subfield following transient ischemia. Int J Mol Med 2019-01-11 [PMID: 31573045] (ICC/IF, Gerbil) Details: Meriones unguiculatus (Mongolian gerbil)	ICC/IF	Gerbil

Array NBP2-59324

• Kir6.1 Antibodies
• Kir6.1 Lysate
• Kir6.1 Protein