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KIR/CD158 Antibody (lirilumab)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
lirilumab
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

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KIR/CD158 Antibody (lirilumab) Summary

Description
Expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'lirilumab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
KIR
Isotype
IgG4
Clonality
Monoclonal
Host
Human
Gene
KIR2DL1
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for KIR/CD158 Antibody (lirilumab)

  • CD158 antigen-like family member A
  • CD158
  • CD158a antigen
  • CD158Ankat1
  • cl-42
  • killer cell immunoglobulin-like receptor 2DL1
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
  • killer Ig receptor
  • killer inhibitory receptor 2-2-1
  • KIR
  • KIR221
  • MHC class I NK cell receptor
  • Natural killer-associated transcript 1
  • NKAT
  • NKAT-1
  • NKAT1KIR-K64
  • p58 killer cell inhibitory receptor KIR-K64
  • p58 natural killer cell receptor clones CL-42/47.11
  • p58 NK cell inhibitory receptor NKR-K6,47.11
  • p58 NK receptor CL-42/47.11
  • p58.1 MHC class-I-specific NK receptor
  • p58.1

Background

The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells. They are involved in recognition of either MHC class I molecules or unknown ligand on target cells and they inhibit cytotoxic activities.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KIR2DL1
Uniprot