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Indoleamine 2,3-dioxygenase/IDO Antibody (998736) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, CyTOF-ready, Flow
Clone
998736
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

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Indoleamine 2,3-dioxygenase/IDO Antibody (998736) [DyLight 550] Summary

Immunogen
E. coli-derived human Indoleamine 2,3-dioxygenase/IDO
Ala2-Gly403
Accession # P14902
Specificity
Detects human Indoleamine 2,3-dioxygenase/IDO in direct ELISAs.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Indoleamine 2,3-dioxygenase/IDO Antibody (998736) [DyLight 550]

  • 3dioxygenase
  • EC 1.13.11.52
  • IDO
  • IDO1
  • IDOIDO-1
  • INDO
  • INDOindole 2,3-dioxygenase
  • Indoleamine 2
  • indoleamine 2,3-dioxygenase 1
  • Indoleamine 2,3-dioxygenase
  • indoleamine-pyrrole 2,3 dioxygenase
  • Indoleamine-pyrrole 2,3-dioxygenase

Background

Gamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.42). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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