Human Total Mer DuoSet IC ELISA, 2 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse orthologs of chicken c-Eyk) constitute the TAM receptor tyrosine kinase subfamily. This RTK subfamily is characterized by an extracellular domain that consists of two Ig-like motifs and two fibronectin type III motifs. These receptors bind the vitamin K-dependent protein Growth Arrest Specific Gene 6 (Gas6). Receptor activation leads to cell proliferation, migration, or the prevention of apoptosis. Cellular signaling through this family of RTKs is involved in hematopoiesis, embryonic development, tumorigenesis, and spermatogenesis.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 3 of 3.

Publications using DYC891-2	Applications	Species
CEJ Waterborg, S Beermann, MGA Broeren, MB Bennink, MI Koenders, PLEM van Lent, WB van den Be, PM van der Kr, FAJ van de Loo Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models Front Immunol, 2018-04-13;9(0):742. 2018-04-13 [PMID: 29706963] (Human)		Human
Ballantine , Lucy, Midgley , Angela, Harris , David, Richards , Ella, Burgess , Sarah, Beresford , Michael Increased soluble phagocytic receptors sMer, sTyro3 and sAxl and reduced phagocytosis in juvenile-onset systemic lupus erythematosus. Pediatr Rheumatol Online J, 2015-04-10;13(0):10. 2015-04-10 [PMID: 25878564] (Human)		Human
Zizzo G, Guerrieri J, Dittman L, Merrill J, Cohen P Circulating levels of soluble MER in lupus reflect M2c activation of monocytes/macrophages, autoantibody specificities and disease activity. Arthritis Res Ther, 2013-01-01;15(6):R212. 2013-01-01 [PMID: 24325951] (Human)		Human

Array DYC891-2

• Mer Antibodies
• Mer Lysate
• Mer Protein
• Mer Proteins and Enzymes
• Mer ELISAs