Home » NT-3 » NT-3 ELISA Kits » Human NT-3 DuoSet ELISA, 15 Plate
Novus Biologicals products are now on bio-techne.com

Human NT-3 DuoSet ELISA, 15 Plate

 (16 Publications)
 See All Related
Submit a Review

Images

 

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

Human NT-3 DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
NTF3

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY267.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human NT-3 DuoSet ELISA, 15 Plate

  • HDNF
  • MGC129711
  • Nerve growth factor 2
  • Neurotrophic factor
  • neurotrophin 3
  • neurotrophin-3
  • NGF2
  • NGF-2
  • NT3
  • NT-3
  • NTF3

Background

Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5. These secreted cytokines are synthesized as prepropeptides that are proteolytically processed to generate the mature proteins. All neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds and all share approximately 55% sequence identity at the amino acid level. Similarly to NGF, bioactive NT-3 is predicted to be a noncovalently linked homodimer.

Human NT-3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT-3. The amino acid sequence of mature NT-3 is identical in human, mouse, and rat. NT-3 transcripts have been detected in the cerebellum, hippocampus, placenta, heart, skin, and skeletal muscle. NT-3 primarily activates the TrkC tyrosine kinase receptor. In addition, NT-3 can activate Trk and TrkB kinase receptors in certain cell systems. NT-3 can also bind with low affinity to the low affinity NGF receptor.

Customers Who Viewed This Item Also Viewed...

BDNF [HRP]
DBD00
N/A BDNF [HRP]
N/A BDNF [HRP]
N/A BDNF [HRP]
(104 Publications)
Species: Hu
Applications: ELISA
beta-NGF
[Unconjugated]
256-GF
SDS-PAGE beta-NGF [Unconjugated]
Bioactivity beta-NGF [Unconjugated]
(58 Publications)
Species: Hu
Applications: BA
NT-4 [Unconjugated]
268-N4/CF
NT-4 [Unconjugated]
(9 Publications)
Species: Hu
Applications: BA
TrkA Antibody
[Unconjugated]
AF1056
Immunohistochemistry TrkA Antibody [Unconjugated]
Western Blot TrkA Antibody [Unconjugated]
Immunohistochemistry TrkA Antibody [Unconjugated]
(44 Publications)
Species: Rt
Applications: IHC, WB
GDNF [Unconjugated]
212-GD
Bioactivity GDNF [Unconjugated]
SDS-PAGE GDNF [Unconjugated]
SEC-MALS GDNF [Unconjugated]
(217 Publications)
Species: Hu
Applications: Bind, BA
TrkC Antibody
[Unconjugated]
AF1404
Western Blot TrkC Antibody [Unconjugated]
Simple Western TrkC Antibody [Unconjugated]
Immunocytochemistry/ Immunofluorescence TrkC Antibody [Unconjugated]
(1 Review)
(66 Publications)
Species: Mu, Rt
Applications: Block, IHC, Simple Western, WB
TrkB Antibody
[Unconjugated]
AF1494
Immunohistochemistry TrkB Antibody [Unconjugated]
Western Blot TrkB Antibody [Unconjugated]
Western Blot TrkB Antibody [Unconjugated]
(12 Reviews)
(80 Publications)
Species: Hu, Mu, Rt
Applications: Block, IHC, Simple Western, WB

NGFR/TNFRSF16/p75NTR A ...
AF1157
Immunohistochemistry NGFR/TNFRSF16/p75NTR Antibody [Unconjugated]
Western Blot NGFR/TNFRSF16/p75NTR Antibody [Unconjugated]
(26 Publications)
Species: Mu
Applications: IHC, WB
tropomyosin-3
Antibody (2E4)
H00007170-M02
Sandwich ELISA tropomyosin-3 Antibody (2E4)
Western Blot tropomyosin-3 Antibody (2E4)
Western Blot tropomyosin-3 Antibody (2E4)
(2 Publications)
Species: Hu
Applications: ELISA, IHC, IHC-P, S-ELISA, WB
CNTF [Unconjugated]
257-NT
SDS-PAGE CNTF [Unconjugated]
Bioactivity CNTF [Unconjugated]
(63 Publications)
Species: Hu
Applications: BA
FGF
basic/FGF2/bFGF [Unco
233-FB
FGF basic/FGF2/bFGF [Unconjugated]
(548 Publications)
Species: Hu
Applications: BA
LEDGF Antibody
(762815) [Unconjugate
MAB3468
Western Blot LEDGF Antibody (762815) [Unconjugated]
Immunocytochemistry LEDGF Antibody (762815) [Unconjugated]
(1 Review)
(1 Publication)
Species: Hu
Applications: ICC, WB
CDP/CUTL1 Antibody
(2A10)
H00001523-M01
Western Blot CDP/CUTL1 Antibody (2A10)
Immunohistochemistry-Paraffin CDP/CUTL1 Antibody (2A10)
ELISA CDP/CUTL1 Antibody (2A10)
(1 Review)
(4 Publications)
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, IP, WB
TNF RII/TNFRSF1B
[HRP]
DRT200
N/A TNF RII/TNFRSF1B [HRP]
N/A TNF RII/TNFRSF1B [HRP]
N/A TNF RII/TNFRSF1B [HRP]
(76 Publications)
Species: Hu
Applications: ELISA
KHSRP Antibody
NBP1-18910
Immunohistochemistry-Paraffin KHSRP Antibody
Immunohistochemistry-Paraffin KHSRP Antibody
Western Blot KHSRP Antibody
(1 Review)
(11 Publications)
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, IP, Simple Western, WB
HCLS1 Antibody
(1A8)
H00003059-M02
Western Blot HCLS1 Antibody (1A8)
Proximity Ligation Assay HCLS1 Antibody (1A8)
Immunohistochemistry-Paraffin HCLS1 Antibody (1A8)
Species: Hu
Applications: ELISA, IHC, IHC-P, KD, PLA, S-ELISA, WB
IL-2 R beta
Antibody (27302)
MAB224
Immunohistochemistry IL-2 R beta Antibody (27302)
Neutralization IL-2 R beta Antibody (27302)
(7 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
Siglec-7/CD328
Antibody [Unconjugate
AF1138
Neutralization Siglec-7/CD328 Antibody [Unconjugated]
(1 Review)
(4 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut, WB

Publications for NT-3 (DY267)(16)

We have publications tested in 2 confirmed species: Human, Rat.


Filter By Application
All Applications
Filter By Species
Human
(13)
Rat
(3)
All Species
Showing Publications 1 - 10 of 16. Show All 16 Publications.
Publications using DY267 Applications Species
Machairiotis, N;Vrachnis, D;Antonakopoulos, N;Loukas, N;Fotiou, A;Pergialiotis, V;Stavros, S;Mantzou, A;Maroudias, G;Iavazzo, C;Kanaka-Gantenbein, C;Drakakis, P;Troupis, T;Vlasis, K;Vrachnis, N; Detection and Quantification of Neurotrophin-3 (NT-3) and Nerve Growth Factor (NGF) Levels in Early Second Trimester Amniotic Fluid: Investigation into a Possible Correlation with Abnormal Fetal Growth Velocity Patterns Journal of clinical medicine 2023-06-19 [PMID: 37373824] (Human) Human
HL Lee, CE Yeum, H Lee, J Oh, JT Kim, WJ Lee, Y Ha, YI Yang, KN Kim Peripheral Nerve-Derived Stem Cell Spheroids Induce Functional Recovery and Repair after Spinal Cord Injury in Rodents International Journal of Molecular Sciences, 2021-04-16;22(8):. 2021-04-16 [PMID: 33923671] (Human) Human
KM Prautsch, A Schmidt, V Paradiso, DJ Schaefer, R Guzman, DF Kalbermatt, S Madduri Modulation of Human Adipose Stem Cells' Neurotrophic Capacity Using a Variety of Growth Factors for Neural Tissue Engineering Applications: Axonal Growth, Transcriptional, and Phosphoproteomic Analyses In Vitro Cells, 2020-08-21;9(9):. 2020-08-21 [PMID: 32839392] (Human) Human
Q Han, JD Ordaz, NK Liu, Z Richardson, W Wu, Y Xia, W Qu, Y Wang, H Dai, YP Zhang, CB Shields, GM Smith, XM Xu Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice Nat Commun, 2019-12-20;10(1):5815. 2019-12-20 [PMID: 31862889] (Human) Human
H Li, Z Yang, W Wang, J Wang, J Zhang, J Liu, T Yang, Y Yang, J Wei, D Lei, X Yang NT-3/TrkC Axis Contributes to the Perineural Invasion and the Poor Prognosis in Human Salivary Adenoid Cystic Carcinoma J Cancer, 2019-10-15;10(24):6065-6073. 2019-10-15 [PMID: 31762816] (Human, Rat) Human, Rat
U Milbreta, J Lin, C Pinese, W Ong, JS Chin, H Shirahama, R Mi, A Williams, ME Bechler, J Wang, C Ffrench-Co, A Hoke, SY Chew Scaffold-Mediated Sustained, Non-viral Delivery of miR-219/miR-338 Promotes CNS Remyelination Mol. Ther., 2018-12-01;0(0):. 2018-12-01 [PMID: 30611662]
Y Zeng, H Han, B Tang, J Chen, D Mao, M Xiong Transplantation of Recombinant Vascular Endothelial Growth Factor (VEGF)189-Neural Stem Cells Downregulates Transient Receptor Potential Vanilloid 1 (TRPV1) and Improves Motor Outcome in Spinal Cord Injury Med. Sci. Monit., 2018-02-21;24(0):1089-1096. 2018-02-21 [PMID: 29466323] (Rat) Rat
Cynthia Azeredo Cordeiro Serum levels of neurotrophic factors in active toxoplasmic retinochoroiditis Braz J Infect Dis, 2016-12-05;0(0):. 2016-12-05 [PMID: 27932287] (Human) Human
Dynamic Response Genes in CD4+ T Cells Reveal a Network of Interactive Proteins that Classifies Disease Activity in Multiple Sclerosis Cell Rep, 2016-09-13;16(11):2928-39. 2016-09-13 [PMID: 27626663] (Human) Human
Yao , L, Daly , W, Newland , B, Yao , S, Wang , W, Chen , B K K, Madigan , N, Windebank , A, Pandit , A Improved axonal regeneration of transected spinal cord mediated by multichannel collagen conduits functionalized with neurotrophin-3 gene. Gene Ther, 2013-07-25;20(12):1149-57. 2013-07-25 [PMID: 23883961] (Human) Human
Show All 16 Publications.

Reviews for NT-3 (DY267) (0)

There are no reviews for NT-3 (DY267). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for NT-3 (DY267) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional NT-3 Products

Blogs on NT-3

There are no specific blogs for NT-3, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Contact Information

Product PDFs

  PDF SDS
  PDF Datasheet
  Request CofA

Review this Product

Be the first to review our Human NT-3 DuoSet ELISA, 15 Plate and receive a gift card or discount.


Bioinformatics

Gene Symbol NTF3