Human MyBPC3 DuoSet ELISA, 5 Plate Summary
Source |
N/A |
Assay Type |
Solid Phase Sandwich ELISA |
Inter-Assay |
|
Intra-Assay |
|
Spike Recovery |
|
Sample Volume |
|
Applications/Dilutions
Dilutions |
|
Application Notes |
No significant interference observed with available related molecules. |
Packaging, Storage & Formulations
Storage |
Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human MyBPC3 DuoSet ELISA, 5 Plate
Background
Cardiac myosin binding protein C3 (MyBPC3) is a 140 kDa thick filament-associated protein located in the crossbridge region of cardiac muscle sarcomeres. It is composed of eight Ig-like domains and three fibronectin 3-like domains and is known to be a physiological substrate of cAMP-dependent protein kinase. MyBPC3 has a role in sarcomeric structure and in the regulation of cardiac muscle contraction. MyBPC3 is released into the coronary effluent during myocardial infarction. Mutations in MyBPC3 are associated with hypertrophic cardiomyopathy.
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