Novus Biologicals products are now on bio-techne.com

Human CCL3/MIP-1 alpha Quantikine ELISA Kit

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Human CCL3/MIP-1 alpha Quantikine ELISA Kit Summary

Background
The Quantikine Human MIP-1 alpha Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure MIP-1 alpha levels in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human MIP-1 alpha and antibodies raised against the recombinant protein. Results obtained for naturally occurring human MIP-1 alpha showed linear curves that were parallel t...o the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural human MIP-1 alpha.
Show More
Specificity
Natural and recombinant human MIP-1 alpha
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CCL3

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DMA00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL3/MIP-1 alpha Quantikine ELISA Kit

  • C-C motif chemokine 3
  • MIP1-(a)
  • AI323804
  • CCL3
  • chemokine (C-C motif) ligand 3
  • G0S19-1
  • LD78a
  • LD78alpha
  • MIP1 alpha
  • MIP-1 alpha
  • MIP1A
  • MIP-1alpha
  • MIP1-alpha
  • PAT 464.1
  • SCYA3
  • SIS-beta

Background

MIP-1 alpha (macrophage inflammatory protein 1 alpha) is a member of the CC or beta chemokine subfamily that was originally purified from the conditioned media of an LPS-stimulated murine macrophage cell line. MIP-1 alpha acts as a chemoattractant to a variety of cells including monocytes, T cells, B cells and eosinophils.

The two human MIP-1 alpha genes arise by duplication/mutation. They code for MIP-1 alpha isoforms CCL3/LD78a and CCL3L1/LD78b, which share 94% amino acid sequence homology. Whereas the human CCL3/LD78a is a single-copy gene, the human CCL3L1/LD78b gene copy number varies within the population. Human CCL3L1/LD78b binds and signals through chemokine receptors CCR1, CCR5. When compared to CCL3/LD78a, CCL3L1/LD78b has higher binding affinity to CCR5, which also functions as a coreceptor for HIV-1 entry. The copy number of CCL3L1 is one of several genetic determinants of HIV-1 susceptibility.

Customers Who Viewed This Item Also Viewed...

DCP00
Species: Hu
Applications: ELISA
DRN00B
Species: Hu
Applications: ELISA
DMB00
Species: Hu
Applications: ELISA
M6000B
Species: Mu
Applications: ELISA
MAB182
Species: Hu
Applications: CyTOF-ready, Flow, ICC, Neut
DIP100
Species: Hu
Applications: ELISA
MAB208
Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), ICC, ICFlow, Neut, Simple Western, WB
MAB145
Species: Hu
Applications: CyTOF-ready, Flow
DY417
Species: Mu
Applications: ELISA
AF-492-NA
Species: Mu
Applications: ELISA(Cap), ELISA(Det), ELISA(Sta), Neut
MM200
Species: Mu
Applications: ELISA
DY453
Species: Mu
Applications: ELISA
MME00
Species: Mu
Applications: ELISA
6507-IL/CF
Species: Hu
Applications: BA
DMD00
Species: Hu
Applications: ELISA
MAB150
Species: Hu
Applications: CyTOF-ready, Flow, IHC
NBP1-19371
Species: Ca, Hu, Mu, Po, Rb, Rt
Applications: Dual ISH-IHC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
DMA00
Species: Hu
Applications: ELISA
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CCL3/MIP-1 alpha (DMA00)(63)

We have publications tested in 4 confirmed species: Human, Primate, Primate - Macaca mulatta (Rhesus Macaque), Primate - Pan troglodytes (Chimpanzee).


Filter By Application
All Applications
Filter By Species
Human
(59)
Primate
(1)
Primate - Macaca mulatta (Rhesus Macaque)
(2)
Primate - Pan troglodytes (Chimpanzee)
(1)
All Species
Showing Publications 1 - 10 of 63. Show All 63 Publications.
Publications using DMA00 Applications Species
Polis, B;Zeman, K;Zakrzewski, K;Fabijan, A;Nowos?awska, E; Peripheral white blood cell patterns in children with hydrocephalus as a response to ventriculo-peritoneal shunt infection PloS one 2024-08-09 [PMID: 39121090] (Human) Human
Scovino, AM;Dahab, EC;Diniz-Lima, I;de Senna Silveira, E;Barroso, SPC;Cardoso, KM;Nico, D;Makhoul, GJ;da Silva-Junior, EB;Freire-de-Lima, CG;Freire-de-Lima, L;Fonseca, LMD;Valente, N;Nacife, V;Machado, A;Araújo, M;Vieira, GF;Pauvolid-Corrêa, A;Siqueira, M;Morrot, A; A Comparative Analysis of Innate Immune Responses and the Structural Characterization of Spike from SARS-CoV-2 Gamma Variants and Subvariants Microorganisms 2024-04-02 [PMID: 38674664] (Human) Human
T Tsai, M Alwees, MA Asaad, J Theile, V Kakkassery, HB Dick, T Schultz, SC Joachim Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy PLoS ONE, 2023-01-20;18(1):e0280488. 2023-01-20 [PMID: 36662891] (Human) Human
E Terpos, I Ntanasis-S, E Kastritis, E Hatjiharis, E Katodritou, E Eleutherak, E Verrou, M Gavriatopo, A Leonidakis, K Manousou, S Delimpasi, P Malandraki, MC Kyrtsonis, M Papaioanno, A Symeonidis, MA Dimopoulos Daratumumab Improves Bone Turnover in Relapsed/Refractory Multiple Myeloma; Phase 2 Study "REBUILD" Oncogene, 2022-06-02;14(11):. 2022-06-02 [PMID: 35681747] (Human) Human
Z Liu, J Liu, T Zhang, L Li, S Zhang, H Jia, Y Xia, M Shi, J Zhang, S Yue, X Chen, J Yu Distinct BTK inhibitors differentially induce apoptosis but similarly suppress chemotaxis and lipid accumulation in mantle cell lymphoma BMC Cancer, 2021-06-26;21(1):732. 2021-06-26 [PMID: 34174847] (Human) Human
ML Mannakanda, MA Kamran, SE Udeabor, MS Hameed, M Ajmal, I Alshahrani Effect of ultrasonic scaling with adjunctive photodynamic therapy in the treatment of gingival inflammation among diabetic patients undergoing fixed orthodontic treatment Photodiagnosis and photodynamic therapy, 2021-05-27;0(0):102360. 2021-05-27 [PMID: 34052421] (Human) Human
E Pandolfi, N Panera, A Alisi, E Carloni, L Russo, I Campagna, C Rizzo, C Concato, G Linardos, L Piccioni, S Jackson, A Villani, F Midulla, AE Tozzi Cytokine expression patterns in hospitalized children with Bordetella pertussis, Rhinovirus or co-infection Scientific Reports, 2021-05-26;11(1):10948. 2021-05-26 [PMID: 34040002] (Human) Human
L Avila, ML Neves, AR Abreu, CR Fiuza, L Fukusawa, N Meziat-Fil, AR Soares San Cognitive functional therapy (CFT) compared with core training exercise (CTE) in patients with failed back surgery syndrome (FBSS): A study protocol for a randomized controlled trial Journal of bodywork and movement therapies, 2020-09-14;26(0):428-434. 2020-09-14 [PMID: 33992278] (Human) Human
E Terpos, I Ntanasis-S, E Katodritou, MC Kyrtsonis, V Douka, E Spanoudaki, A Papatheodo, E Eleutherak, N Kanellias, M Gavriatopo, P Makras, E Kastritis, MA Dimopoulos Carfilzomib Improves Bone Metabolism in Patients with Advanced Relapsed/Refractory Multiple Myeloma: Results of the CarMMa Study Cancers, 2021-03-12;13(6):. 2021-03-12 [PMID: 33809268] (Human) Human
S Sendic, L Mansouri, S Lundberg, A Nopp, SH Jacobson, J Lundahl B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy PLoS ONE, 2021-03-19;16(3):e0248056. 2021-03-19 [PMID: 33740017] (Human) Human
Show All 63 Publications.

Reviews for CCL3/MIP-1 alpha (DMA00) (0)

There are no reviews for CCL3/MIP-1 alpha (DMA00). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CCL3/MIP-1 alpha (DMA00) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional CCL3/MIP-1 alpha Products

Blogs on CCL3/MIP-1 alpha

There are no specific blogs for CCL3/MIP-1 alpha, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Review this Product

Be the first to review our Human CCL3/MIP-1 alpha Quantikine ELISA Kit and receive a gift card or discount.

Bioinformatics

Gene Symbol CCL3